3 results match your criteria: "Hadassah Medical Center and Faculty of Medicine Hebrew University of Jerusalem[Affiliation]"
In Response.
A A Pract
July 2024
General Intensive Care Unit Department of Anesthesiology, Critical Care and Pain Medicine Hadassah Medical Center and Faculty of Medicine Hebrew University of Jerusalem Jerusalem, Israel
Effect of pentoxifylline on colon cancer patients treated with chemotherapy (Part I).
Tumour Biol
January 2022
Department of Oncology, Hadassah Medical Center and Faculty of Medicine Hebrew University of Jerusalem, Jerusalem, Israel.
Background: Cancer progression is associated with significant systemic clinical manifestations including cachexia induced weight loss and anorexia. Pentoxifylline (PTX) is a drug that has been shown to have multiple beneficial effects in cancer patients through its anti-inflammatory properties.
Main Objective: To evaluate PTX effects on colon cancer patients treated with chemotherapy.
Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency.
J Clin Immunol
August 2021
Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW, 2010, Australia.
Article Synopsis
- Biallelic mutations in the IL21R gene lead to combined immunodeficiency, often resulting in severe infections including cryptosporidiosis, with a study analyzing 13 patients revealing eight unique mutations.
- Common symptoms included recurrent bacterial, fungal, and viral infections, with additional issues like asthma and skin diseases, while many patients showed low antibody levels and immune cell deficiencies.
- Hematopoietic stem cell transplantation (HSCT) had a poor success rate, with only 33.3% survival among transplanted patients and 57.1% mortality in non-transplanted cases, highlighting the impact of organ damage from chronic infections on outcomes.