7 results match your criteria: "Hackensack Meridian JFK University Medical Center[Affiliation]"
Exploring arteriovenous malformations patient sentiments through 1401 social media posts.
Interv Neuroradiol
September 2024
Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA.
Article Synopsis
- Social media helps patients with rare diseases, like arteriovenous malformations (AVM), connect and share experiences, as shown in an analysis of posts from platforms like Twitter, Instagram, and TikTok.
- The study found that common themes in posts included raising awareness (87%), recounting symptoms (50.2%), and sharing positivity (17.5%), with most engagement coming from female users.
- Social media serves as a crucial platform for AVM patients to connect with others and discuss their experiences, increasing public awareness about the condition.
Diagnostic Utility of Cerebrospinal Fluid Biomarkers in Patients with Rapidly Progressive Dementia.
Ann Neurol
February 2024
Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA.
Article Synopsis
- This study aims to enhance diagnostic accuracy for rapidly progressive dementia (RPD) by analyzing various cerebrospinal fluid (CSF) biomarkers, considering the overlap in symptoms and diagnostic challenges among different dementia types.
- Researchers compared biomarker levels in 78 patients with RPD, 35 with typical neurodegenerative diseases, and 72 control subjects, focusing on multiple factors like neuroinflammation and neurodegeneration.
- Results indicate that specific biomarkers can effectively distinguish between different underlying causes of RPD, with a multivariate model achieving 89% accuracy in identifying treatment-responsive cases.
Nrf2 as a Potential Therapeutic Target for Traumatic Brain Injury.
J Integr Neurosci
June 2023
Laboratory of CNS Injury and Molecular Therapy, JFK Neuroscience Institute, Hackensack Meridian JFK University Medical Center, Edison, NJ 08820, USA.
In this review, we discuss the possibility and feasibility of nuclear factor erythroid 2-related factor 2 (Nrf2) as a therapeutic target to minimize the devastating effects of a brain injury. To complete this review, comprehensive literature searches were conducted in MEDLINE, PubMed, Embase, and PsycINFO databases for English scientific peer-reviewed articles through December 2022. This short review addressed the different sources of oxidative stress and its effects on blood-brain barrier (BBB) dysfunction, mitochondrial damage, and changes in a variety of inflammatory molecules associated with central nervous system (CNS) injury.
View Article and Find Full Text PDFRetrieval of Migrated Coils From Distal Cerebral Vasculature Using Stent Retriever: A Case Series.
Cureus
April 2023
Department of Neurology, Hackensack Meridian JFK University Medical Center, Edison, USA.
The incidence of coil dislocation during an endovascular embolization of intracranial aneurysm is low but it can lead to serious thrombo-embolic complications. Therefore, coil displacement/migration often requires either retrieval or fixation of the errant coil with a stent. There are no standard recommended methods of coil retrieval.
View Article and Find Full Text PDFReal-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practice.
Eur J Neurol
July 2023
Mayo Clinic, Department of Neurology, Jacksonville, Florida, USA.
Article Synopsis
- Real-time quaking-induced conversion (RT-QuIC) assays are a valuable but imperfect method for detecting prions, as some patients can receive false negative results despite having prion diseases.
- A study involving 113 patients showed an 88.5% sensitivity for RT-QuIC, with younger patients being more likely to test negative and showing lower levels of certain biomarkers.
- The findings suggest that an RT-QuIC negative result may indicate a slower progression of the disease, highlighting the importance of using additional diagnostic tests for accurate evaluation of suspected prion disease cases.*
Aging with Traumatic Brain Injury: Deleterious Effects of Injury Chronicity Are Most Pronounced in Later Life.
J Neurotrauma
October 2021
Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Understanding the effects of age on longitudinal traumatic brain injury (TBI) outcomes requires attention to both chronic and evolving TBI effects and age-related changes in health and function. The present study examines the independent and interactive effects of aging and chronicity on functional outcomes after TBI. We leveraged a well-defined cohort of individuals who sustained a moderate/severe TBI and received acute inpatient rehabilitation at specialized centers with high follow up rate as part of their involvement in the TBI Model Systems longitudinal study.
View Article and Find Full Text PDFPhase-dependent transcranial magnetic stimulation of the lesioned hemisphere is accurate after stroke.
Brain Stimul
July 2020
Human Cortical Physiology and Neurorehabilitation Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.