Nitrogen Deposition Weakens Soil Carbon Control of Nitrogen Dynamics Across the Contiguous United States.

Anthropogenic nitrogen (N) deposition is unequally distributed across space and time, with inputs to terrestrial ecosystems impacted by industry regulations and variations in human activity. Soil carbon (C) content normally controls the fraction of mineralized N that is nitrified (ƒ), affecting N bioavailability for plants and microbes. However, it is unknown whether N deposition has modified the relationships among soil C, net N mineralization, and net nitrification.

Polygenic response to selection by transgenic Bt-expressing crops in wild Helicoverpa zea and characterization of a major effect locus.

Strong and shifting selective pressures of the Anthropocene are rapidly shaping phenomes and genomes of organisms worldwide. Crops expressing pesticidal proteins from Bacillus thuringiensis (Bt) represent one major selective force on insect genomes. Here we characterize a rapid response to selection by Bt crops in a major crop pest, Helicoverpa zea.

Triple inhaler therapy in adolescents and adults with moderate or severe persistent asthma.

Expert guidelines, meta-analyses, and multiple randomized controlled trials have demonstrated the effectiveness of long-acting inhaled antimuscarinic agents (LAMAs) as an additive medication for patients with poorly controlled moderate or severe persistent asthma. LAMAs play an essential role in blocking acetylcholine binding to muscarinic receptors and reducing bronchoconstriction and mucus production. By adding this medication to other combination inhalers, patients can use a triple inhaler to improve FEV1 values and reduce exacerbations.

Size-Up, Size-Down: Accuracy of Component Sizing with Computerized Tomography and Robotic-Assisted Total Knee Arthroplasty.

Templating prior to total knee arthroplasty (TKA) can help to improve surgical efficiency and potentially improve alignment and outcomes. The purpose of this article is to evaluate the ability of computed tomography (CT)-based preoperative templating to accurately predict implant sizes. A total of 724 Stryker MAKO robotic-assisted TKA cases were retrospectively evaluated from a prospectively collected database between January 2020 and October 2023.

Validation of the Nurse Practitioner Knowledge and Attitudes of Patient Obesity Scale: A pilot study.

Background: Obesity is a chronic, complex, relapsing disease requiring medical intervention that has reached epidemic proportions globally. Most patients are still experiencing bias and stigma related to their disease-even by health care providers. Our goal in this pilot study is twofold: to develop a scale to accurately measure nurse practitioner knowledge and attitude regarding the disease of obesity to determine whether bias exists and to potentially identify gaps in knowledge that can be targeted with future educational interventions.

A New Species of Chopra, 1923 (Isopoda, Epicaridea, Bopyridae) Parasitizing Shrimps of the Genus Spence Bate, 1888 (Decapoda, Caridea, Alpheidae) from the Fernando de Noronha Archipelago, Brazil.

A new species of Chopra, 1923, a parasitic isopod genus of the family Bopyridae found parasitizing two species of the snapping-shrimp genus Spence Bate, 1888, is described from Brazil. This is the first record of in the Atlantic Ocean, and the first species of bopyrid parasite recorded from the Fernando de Noronha archipelago in northeastern Brazil. Females of sp.

Radio Frequency Ablation of Enlarged Thyroid Nodules: A Case Report.

In the thyroid, abnormal growth can be the result of either benign thyroid nodules (BTNs) or differentiated thyroid cancers (DTCs). If the growth is confirmed to be a DTC, surgical intervention, either a partial or total thyroidectomy, is recommended. Although a majority of BTNs do not require treatment, intervention becomes necessary when nodules cause symptoms, enlargement, or a rare suspicion of malignancy.

The impact of cerebrovascular steno-occlusive disease subtype on surgical and clinical outcomes after direct STA-MCA bypass surgery.

Objective: Although well-established in moyamoya disease (MMD), the role of direct superficial temporal artery (STA) to middle cerebral artery (MCA) bypass in non-MMD (N-MMD) cerebrovascular steno-occlusive syndromes remains controversial. Nonetheless, the recurrent stroke risk in patients with N-MMD, despite best medical management, remains exceedingly high-especially for those suffering from hypoperfusion-related ischemia. The study objective was to determine the relative safety and efficacy profiles of direct STA-MCA bypass surgery for MMD and N-MMD patients in a large contemporary cohort.

Association of anaesthesia-directed sedation with unplanned discharge to a nursing home following non-ambulatory interventional radiology and endoscopic procedures: a retrospective cohort study.

Introduction: Interventional radiology procedures and endoscopies are performed commonly worldwide, often necessitating pharmacological sedation to optimise patient comfort. It is unclear to what extent non-anaesthetists should provide procedural sedation.

Methods: We studied adult patients who previously lived independently and underwent a non-ambulatory interventional radiology or gastroenterology procedure under anaesthetist-directed or non-anaesthetist-directed sedation at a large healthcare network.

Air Passengers' Risk of SARS-CoV-2 Infection with a 14-day Quarantine and Accuracy Assessment of a Symptom-based Screening System at an Airport.

Objectives: This study aimed to validate the risk of SARS-CoV-2 infection, identify infection risk factors among air passengers subject to a 14-day mandatory quarantine, and evaluate the accuracy of mass symptom-based screening criteria at an airport.

Methods: This retrospective cohort study analyzed data from 116,004 air passengers who entered Thailand through Suvarnabhumi Airport in Bangkok from April to September 2020. The incidence of SARS-CoV-2 infection, risk characteristics, and accuracy indices of symptom-based screening were calculated.

A Review of Pharmacologic and Non-Pharmacologic Therapies in the Management of Irritable Bowel Syndrome: Current Recommendations and Evidence.

Irritable bowel syndrome (IBS) is a highly prevalent and debilitating disorder of gut-brain interaction (DGBI) affecting millions globally. It imposes a significant burden on healthcare systems and is a leading cause of workplace absenteeism. IBS is classified into several subtypes based on predominant presenting symptoms, including IBS with constipation (IBS-C) and IBS with diarrhea (IBS-D), with each requiring targeted approaches to treatment.

Stable π Radical BDPA: Adsorption on Cu(100) and Survival of Spin.

The adsorption of the radical α,ɣ-bisdiphenylene-β-phenylallyl (BDPA) molecule to the Cu(100) surface was studied using scanning tunnelling microscopy (STM), scanning tunnelling spectroscopy (STS), and density functional theory (DFT) calculations accounting for dispersion forces. BDPA on Cu(100) was observed to align preferentially along directions due to weak Cu-C chemisorption between fluorenyl carbons with the underlying copper atoms. The curved shape of the BDPA molecule on Cu(100) can be ascribed to the lack of molecular orbital character on the phenyl substituent.

Microbial genetic variation impacts host eco-immunological strategies and microparasite fitness in Lyme borreliae-reptile system.

Tolerance and resistance are two host eco-immunological strategies in response to microparasite invasion. In the strategy of "resistance", host responses are induced to decrease microparasite replication while the "tolerance" strategy allows hosts coexistence with microparasites by minimizing responses to avoid immune-mediated damage. The causative agent of Lyme disease is a group of genotypically diverse bacterial species, Borrelia burgdorferi sensu lato (Bb), which is transmitted by Ixodes ticks and persists in different reservoir animals.

Understanding the Impact of COVID-19 Lockdowns on Older Adults' Routines and Well-being: 3 Case Reports.

The COVID-19 pandemic has significantly impacted the daily lives of older adults. Three case reports illustrate how individuals have coped with loss, maintained routines, and faced emotional challenges. Understanding these experiences can guide efforts to promote the well-being and resilience of older adults during this time.