17 results match your criteria: "HIV-1 Associated Opportunistic Infections - Cytomegalovirus Encephalitis"
Brain Nerve
March 2013
Tokyo Metropolitan Cancer and Infectious Disease Center, Japan.
Human immunodeficiency virus (HIV) induces acquired immunodeficiency syndrome (AIDS) in humans. Neurological complications occur frequently in patients with AIDS. About 20 to 40% of all these patients develop neurological symptoms, and in about 10% of AIDS patients, the onset of the disease is characterized by neurological symptoms.
View Article and Find Full Text PDFCNS Drugs
February 2012
Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287-7613, USA.
J Neuroimmunol
November 2005
Clinic of Infectious Diseases, San Raffaele Hospital, Milan, Italy.
Interferon-gamma-inducible protein (IP-10 or CXCL10) is a potent chemoattractant and has been suggested to enhance retrovirus infection and mediate neuronal injury. In order to assess this chemokine in central nervous system (CNS) HIV infection, we measured the cerebrospinal fluid (CSF) and plasma concentrations of CXCL10 by immunoassay in samples derived from 97 HIV-infected subjects across a spectrum of immunological progression and CNS complications and from 16 HIV seronegative control subjects studied at three clinical centers between 1994 and 2001. We also examined changes in the CSF and plasma CXCL10 concentrations in 30 subjects starting and three stopping antiretroviral therapy.
View Article and Find Full Text PDFAim: To analyse the results of a 15-year study of opportunistic diseases in AIDS patients.
Material And Methods: The spectrum of opportunistic diseases were made in AIDS patients in respect to clinical, laboratory and autopsy data for the periods: 1987-1992 (n = 27, 25 deaths--92.6%), 1993-1997 (n = 95, 58 deaths--61.
Ann Neurol
May 2004
Clinic of Infectious Diseases, San Raffaele Scientific Institute, University of Milan, Italy.
AIDS Res Hum Retroviruses
August 2000
Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York 10016, USA.
J Neurovirol
April 2000
Department of Biochemistry and Molecular Biology, University of Bari, 70126 Bari, Italy.
Nihon Rinsho
January 1998
Department of Internal Medicine, Kushiro Rosai Hospital.
Persons with advanced HIV infection may have active HCMV infection for months before clinically recognized HCMV disease. The qualitative detection of HCMV-DNA in plasma by PCR is more useful than either urine or blood culture in identifying over time those persons with advanced HIV disease who will develop HCMV disease. Quantitation of HCMV DNA in plasma has identified an association between levels of HCMV DNA in plasma and risk for development of HCMV disease.
View Article and Find Full Text PDFNeuroimaging Clin N Am
August 1997
Department of Neurology, University of Kentucky College of Medicine, Lexington, USA.
The spectrum of opportunistic infections occurring in association with human-immunodeficiency virus, type 1, is very broad. These infections develop most frequently in the setting of advanced immunosuppression. There is no part of the neuraxis that is immune to these complications and the concurrence of more than one infectious illness may always be considered.
View Article and Find Full Text PDFClin Infect Dis
April 1996
Services des Maladies Infectieuses et tropicales, Hôpital de l'Institut Pasteur, Paris.
We reviewed cases of cytomegalovirus (CMV) infection of the central nervous system (CNS) that initially masqueraded as tumors in 37 of 543 consecutive patients infected with human immunodeficiency virus (HIV) and CMV who were seen at the Pasteur Institute Hospital and Saint-Louis Hospital (Paris) between 1992 and 1994. We detail the clinical features of three patients who presented with ring-enhanced space-occupying lesions mimicking CNS tumors. They were all profoundly immunodepressed (mean CD4 cell count, 13/mm3).
View Article and Find Full Text PDFJ NeuroAIDS
April 2016
, Level 2, 376 Victoria Street, Syndey NSW, 2010, Australia.
A prospective, case-control study was undertaken to characterise seizures occurring in the context of human immunodeficiency type-1 (HIV-1) infection. Fifty consecutive patients with a documented seizure were enrolled along with fifty control patients. Among cases the median CD4 cell count was 8/mm3 and 84% had a prior AIDS defining illness; 14/mm3 and 80% among the control group.
View Article and Find Full Text PDFBildgebung
December 1995
Neurologische Klinik, Universität Düsseldorf, Germany.
J Neurol
June 1994
Neurologische Klinik und Poliklinik, Georg-August-Universität Göttingen, Germany.
We evaluated 49 paired cerebrospinal fluid (CSF) and serum samples of 35 patients infected with the human immunodeficiency virus type 1 (HIV-1) for laboratory evidence of cytomegalovirus (CMV) infection. The patients were grouped according to clinical criteria as probable CMV encephalitis/polyradiculomyelitis, CMV retinitis, cerebral toxoplasmosis, progressive multifocal leukoencephalopathy, HIV-1-related cognitive/motor complex, HIV-1-associated myelopathy, and other neurological diseases. Paired CSF and serum samples were analysed for CMV deoxyribonucleic acid (DNA) by polymerase chain reaction (PCR), quantitative intrathecal synthesis of immunoglobulin G (IgG) antibodies specific for recombinant phosphoprotein 150 (pp150) of CMV and CMV-specific serum IgM.
View Article and Find Full Text PDFBackground: HIV disease is epidemic in Africa, but associated mortality, underlying pathology and CD4+ T-lymphocyte counts have not previously been evaluated in a representative study. Such data help to determine the management of HIV-positive people. Both HIV-1 and HIV-2 infections are prevalent in Côte d'Ivoire, and the pathology of HIV-2 infection in Africa is unclear.
View Article and Find Full Text PDFRev Soc Bras Med Trop
April 1994
Departamento de Patologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo.
The nervous system is frequently involved in patients with AIDS. The lesions can be due to the human immunodeficiency virus (HIV), to opportunistic agents, to the development of tumours, and to occasional nonspecific factors, such as circulatory, metabolic and degenerative changes. The changes directly related to the presence of the HIV include the HIV encephalitis and leucoencephalopathy, the diffuse polydystrophy and the vacuolar myelopathy.
View Article and Find Full Text PDFCan J Neurol Sci
November 1992
Department of Pathology, UCLA Center for Health Sciences 90024-1732.
Neuropathological findings from 39 acquired immune deficiency syndrome (AIDS) autopsies of primarily neurologically symptomatic patients and 7 brain biopsies from AIDS patients performed at St. Paul's Hospital, Vancouver, British Columbia are reported. Autopsy findings included human immunodeficiency virus-1 (HIV)-type multinucleated giant cell (MNGC)-associated encephalitis seen in 17 patients, toxoplasmosis in 7 patients, and cytomegalovirus encephalitis and/or microglial nodule-associated nuclear inclusions in brain parenchyma in 9 patients.
View Article and Find Full Text PDFJ Neurochem
October 1992
Department of Neurology, University of Minnesota, Minneapolis 55455-0323.