4 results match your criteria: "Hôpitaux Universitaires Paris-Sud-Assistance Publique-Hôpitaux de Paris (AP-HP)[Affiliation]"
Noradrenaline for haemodynamic control in obstetric anaesthesia: Is it now a suitable alternative to phenylephrine?
Anaesth Crit Care Pain Med
December 2019
Department of Anaesthesiology, Sidra Medicine, Doha, Qatar.
Valine 11 and phenylalanine 13 have a greater impact on the T-cell response to citrullinated peptides than the 70-74 shared epitope of the DRB1 molecule in macaques.
Ann Rheum Dis
July 2019
Rheumatology Department, Hôpitaux Universitaires Paris-Sud-Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Sud- CEA-INSERM U1184 'Immunology of viral infections and autoimmune diseases', Le Kremlin-Bicêtre, France
Objectives: Various rheumatoid arthritis (RA) HLA-DRB-1 risk haplotypes have been regrouped under the shared epitope (SE) in position 70-74. The presence of Valine in position 11 (Val11) and phenylalanine in position 13 (Phe13) are also associated with RA, but it is impossible to differentiate their role compared with the SE since they are in strong linkage disequilibrium (LD) in humans. Similar to humans, certain macaques express the SE (H6).
View Article and Find Full Text PDFInteraction between B-cell activation factor and methotrexate impacts immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis.
Ann Rheum Dis
February 2019
Rheumatology Department, Université Paris-Sud, INSERM UMR1184, Immunology of Viral Infections and Autoimmune Diseases, Hôpitaux Universitaires Paris-Sud-Assistance Publique-Hôpitaux de Paris (AP-HP), Le Kremlin Bicêtre, France
Methotrexate and BAFF interaction prevents immunization against TNF inhibitors.
Ann Rheum Dis
October 2018
Rheumatology Department, Université Paris-Sud-CEA-INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases, Hôpitaux Universitaires Paris-Sud-Assistance Publique-Hôpitaux de Paris (AP-HP), Le Kremlin Bicêtre, France.
Objectives: TNF inhibitors (TNFi) can induce anti-drug antibodies (ADA) in patients with autoimmune diseases (AID) leading to clinical resistance. We explored a new way of using methotrexate (MTX) to decrease this risk of immunisation.
Methods: We treated BAFF transgenic (BAFFtg) mice, a model of AID in which immunisation against biologic drugs is high, with different TNFi.