5 results match your criteria: "Hôpitaux Universitaires Paris-Seine-St-Denis[Affiliation]"

Background: Neoadjuvant fluoropyrimidine (5FU or capecitabine)-based chemoradiotherapy (CRT) has been considered the standard of care for locally advanced rectal cancer (LARC). Whether addition of oxaliplatin (OXP) will further improve clinical outcomes is still unclear.

Methods: To identify clinical trials combining oxaliplatin in preoperative CRT or perioperative chemotherapy for LARC published until March 2021, we searched PubMed and the Cochrane Library.

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Objectives: The high risk of SARS-CoV-2 transmission in homeless communities requires adapted prevention strategies for field-based healthcare workers (HCWs). Rapid serological tests (RSTs) could be an invaluable tool for HCWs to control COVID-19 transmission. This study assesses the benefits of RSTs for HCWs in Marseille, France.

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Lung function tests have a major role in respiratory medicine. Training in lung function tests is variable within the European Union. In this study, we have shown that an internship in a lung function tests laboratory significantly improved the technical and diagnostic skills of French respiratory trainees.

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The management of opiate use disorders in France: results of an observational survey of general practitioners.

Addict Sci Clin Pract

June 2015

Laboratoire de psychiatrie, Département d'addictologie, Centre hospitalier Charles Perrens, 146 bis, rue Léo Saignat, Bordeaux, 33076, France.

Background: When opioid-agonist treatments were approved in France in 1995, opiate use disorders began to be managed and treated by general practitioners (GPs), who have since then been encouraged to treat substance use disorders (SUDs) for heroin and other illegal substances. The objective of this study was to describe rates of: 1) SUDs in general practices in France; 2) characteristics of GPs treating SUDs; and 3) clinical practices surrounding SUDs. To place these data in the context of SUD treatment, we also gathered information from practicing SUD specialists.

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GH administration rescues fatty liver regeneration impairment by restoring GH/EGFR pathway deficiency.

Endocrinology

July 2014

Inserm (A.C.H., A.Z.-S., C.P.-B., V.F., N.H., C.V., K.B., V.B., H.G., J.-E.G.), U1016, Institut Cochin, 75014, Paris, France; CNRS (A.C.H., A.Z.-S., C.P.-B., V.F., N.H., C.V., K.B., V.B., H.G., J.-E.G.), UMR8104, 75014, Paris, France; Université Paris Descartes (A.C.H., A.Z.-S., C.P.-B., V.F., N.H., C.V., K.B., V.B., H.G., J.-E.G.), Sorbonne Paris Cité, Faculté de Médecine 75006, Paris, France; and Service de Chirurgie Digestive et Métabolique (N.H., M.Z., C.V.), Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Seine-St-Denis, Hôpital Jean Verdier, 93140, Bondy, France.

GH pathway has been shown to play a major role in liver regeneration through the control of epidermal growth factor receptor (EGFR) activation. This pathway is down-regulated in nonalcoholic fatty liver disease. Because regeneration is known to be impaired in fatty livers, we wondered whether a deregulation of the GH/EGFR pathway could explain this deficiency.

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