279 results match your criteria: "Hôpital Universitaire Nord[Affiliation]"

International Consensus Statement on Platelet Function and Genetic Testing in Percutaneous Coronary Intervention: 2024 Update.

JACC Cardiovasc Interv

November 2024

Medizinische Klinik und Poliklinik I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany; Privatklinik Lauterbacher Mühle am Ostsee, Seeshaupt, Germany.

Current evidence indicates that dual antiplatelet therapy with aspirin plus a P2Y inhibitor is essential for the prevention of thrombotic events after percutaneous coronary interventions. However, dual antiplatelet therapy is associated with increased bleeding which may outweigh the benefits. This has set the foundations for customizing antiplatelet treatments to the individual patient.

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Retinopathy of prematurity (ROP, ORPHA: 90050) is the main cause of visual impairment in preterm infants and the leading preventable cause of childhood blindness in high- and middle-income countries. However, severe stages of the disease remain rare. While screening recommendations for the disease are well-established in France, management of ROP requiring treatment is less standardized, especially since new therapeutic options have been approval on this indication.

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NCB-PP® locking plates outcomes in the treatment of periprosthetic femoral fractures. Analysis of a retrospective cohort of 89 patients.

Orthop Traumatol Surg Res

September 2024

Service de Chirurgie Orthopédique et Traumatologique, Centre Hospitalo-Universitaire Nord, Hôpital Nord, chemin des Bourrely, 13015 Marseille, France.

Introduction: The management of periprosthetic femoral fractures is particularly complex in an elderly, frail population, with an increasing incidence due to the increase in femoral prosthesis surgery. The use of locking plates is now widely recommended. The primary objective of this study was to present the results of NCB-PP® locking plates in the management of periprosthetic femoral fractures.

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[How do women in Réunion Island want to perform HPV test on vaginal sampling as part of cervical cancer screening?].

Gynecol Obstet Fertil Senol

September 2024

UFR santé, université de la Réunion, 40, avenue de Soweto, Terre-Sainte, BP 373, 97455 Saint-Pierre cedex, Réunion; Service de gynécologie-obstétrique, centre hospitalier universitaire Sud-Réunion, BP 350, 97448 Saint-Pierre cedex, Réunion; Inserm, CIC 1410, Reunion University Hospital, 97448 Saint-Pierre, Réunion. Electronic address:

Article Synopsis
  • A study in La Reunion examined women's preferences for vaginal sampling (VS) for HPV testing as part of cervical cancer (CC) screening, focusing on women aged 30 to 65 who were concerned about their screening status.
  • A total of 202 women participated, with results showing that many preferred to collect the sampling kit from a healthcare provider but also favored self-sampling (SS) at home, with clear instructions provided in French and visual aids.
  • The findings indicated no significant difference in preferences between women who were up to date on screenings versus those who were not, suggesting a potential need for further research on the implementation of self-sampling for a broader population.
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Purpose: This study aims to assess the safety and efficacy of the fenestrated Anaconda device for the treatment of complex aortic aneurysms over 1 year in daily clinical practice.

Materials And Methods: All patients who received the graft between October 2019 and October 2020 were prospectively enrolled in an observational, multicenter national registry. The primary endpoint was the aneurysm-related 1-year mortality rate.

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Background: Severe trauma is the leading cause of disability and mortality in the patients under 35 years of age. Surgical site infections (SSI) represent a significant complication in this patient population. However, they are often inadequately investigated, potentially impacting the quality of patient outcomes.

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Osseous Outcomes of Cleft Alveolar Bone Grafting with Allograft and Platelet-Rich Fibrin: Preliminary Study with Radiological Outcome.

Cleft Palate Craniofac J

August 2024

Department of Pediatric Cranio-Maxillo-Facial Surgery, Hôpital Femme Mère Enfant, Lyon Bron, France.

Objective: Cleft lip and palate are the most common craniofacial malformations worldwide. The alveolar cleft is treated with a bone graft, between 4 and 7 years of age in mixed dentition. This is an important step because it provides good quality jawbone and a better support of the lip and the alar cartilage on the side of the cleft.

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Introduction: Treatment options for open tibial shaft fractures include external fixation with or without early conversion to internal fixation.

Objectives: The aim of this study was to describe 1) early conversion to internal fixation and definitive external fixation and 2) in case of conversion, to identify risk factors for complications.

Methods: Seventy-two external fixations of open fractures of the tibial shaft (Gustilo classification, 7 fractures (9.

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Article Synopsis
  • The study aimed to assess the long-term effects of using a hybrid closed loop (HCL) system on glucose levels and body mass index (BMI) in children with type 1 diabetes during puberty.* -
  • Over 30 months, data showed that improvements in HbA1c levels were maintained and BMI scores remained stable in participants, with no severe hypoglycemic events and only one unrelated ketoacidosis case.* -
  • Findings suggest that prolonged HCL usage can help manage glucose control during puberty without negatively affecting BMI in children with type 1 diabetes.*
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In preterm infants, early nutrient intake during the first week of life often depends on parenteral nutrition. This study aimed to evaluate the influence of standardized parenteral nutrition using three-in-one double-chamber solutions (3-in-1 STD-PN) on early neonatal growth in a cohort of moderately preterm (MP) infants. This population-based, observational cohort study included preterm infants admitted to neonatal centers in the southeast regional perinatal network in France.

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Interest of thoracic ultrasound after cardiac surgery or interventional cardiology.

World J Cardiol

March 2024

Service d'Explorations Fonctionnelles Respiratoires, Centre Hospitalier Universitaire Nord, Assistance Publique des Hôpitaux de Marseille, Marseille 13015, France.

Thoracic ultrasound has attracted much interest in detecting pleural effusion or pulmonary consolidation after cardiac surgery. In 2016, Trovato reported, in the , the interest of using, in addition to echocardiography, thoracic ultrasound. In this editorial, we highlight the value of assessing diaphragm function after cardiac surgery and interventional cardiology procedures.

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Predictive factors of the postoperative proptosis recovery in surgery of spheno-orbital meningiomas.

Acta Neurochir (Wien)

April 2024

Assistance Publique - Hôpitaux de Marseille, AP-HM, Hôpital Universitaire Nord, Neurochirurgie Adulte, Chemin Des Bourrely, 13015, Marseille, France.

Objective: This study aimed to identify factors affecting proptosis recovery in spheno-orbital meningioma (SOM) surgery and assess functional and oncological outcomes.

Methods: Data from 32 consecutive SOM surgery cases (2002-2021) were analyzed. Clinical, radiological, operative, and oncological parameters were examined.

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Vγ9Vδ2 T cells play a key role in the innate immune response to viral infections through butyrophilin 3A (BTN3A). Here, we report blood Vγ9Vδ2 T cells decreased in clinically mild COVID-19 compared to healthy volunteers, and this was maintained up to 28 days and in the recovery period. Terminally differentiated Vγ9Vδ2 T cells tended to be enriched on the day of diagnosis, 28 days after, and during the recovery period.

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[Prevalence of menorrhagia among women in Reunion Island].

Gynecol Obstet Fertil Senol

December 2024

Université de la Réunion, UFR santé, 40, avenue de Soweto - Terre-Sainte, BP 373, 97455 Saint-Pierre cedex, Réunion; Service de gynécologie-obstétrique, centre hospitalier universitaire Sud-Réunion, BP 350, 97448 Saint-Pierre cedex, Réunion; Inserm, CIC 1410, Reunion University Hospital, 97448 Saint-Pierre, France. Electronic address:

Objectives: To estimate the prevalence of menorrhagia in women in Reunion Island using the Higham score, to evaluate self-reporting as an alternative diagnostic method, and to study women's level of knowledge about menorrhagia and its impact on their quality of life.

Methods: This was a descriptive, cross-sectional observational study involving 185 adult women with menstrual periods living in Reunion Island. Women volunteered to answer an online self-questionnaire proposed by healthcare professionals from January to May 2023 in Reunion Island.

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Article Synopsis
  • * There was no increased risk of acute kidney injury (AKI) in patients receiving combination therapy, suggesting it may not be more harmful than single-drug therapy.
  • * The research utilized data from a multicenter database and included various analyses based on patient characteristics and the resistance profiles of the bacteria involved, indicating a comprehensive approach to assessing treatment outcomes.
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[Determinants of papillomavirus vaccination in Mayotte: A qualitative study among general practitioners].

Gynecol Obstet Fertil Senol

February 2024

Université de la Réunion, UFR santé, 40, avenue de Soweto, Terre Sainte, BP 373, 97455 Saint-Pierre cedex, La Réunion, France; Service de gynécologie-obstétrique, centre hospitalier universitaire Sud-Réunion, BP 350, 97448 Saint-Pierre cedex, La Réunion, France; Inserm, CIC 1410, Reunion University Hospital, 97448 Saint-Pierre, France. Electronic address:

Objectives: In Mayotte, cervical cancer represents the second cause of cancer mortality in women. Vaccination coverage against papillomavirus and screening rates are difficult to quantify but among the lowest in France. Added to this is an under-calibrated health system, which does not allow optimal treatment of cancers on site.

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Objective: The aim was to describe the baseline characteristics of French patients referred with acute limb ischaemia (ALI), and their clinical management and outcome (death, amputation).

Methods: This retrospective observational cohort study used the National Health Data System. All adults hospitalised for ALI who underwent revascularisation with an endovascular or open surgical approach between 1 January 2015 and 31 December 2020 were included and followed up until death or the end of the study (31 December 2021).

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Preliminary results in tracheal replacement using stented aortic matrices for primary extensive tracheal cancer.

JTCVS Tech

October 2023

Chirurgie Thoracique et Vasculaire, Assistance Publique - Hôpitaux de Paris, Hôpitaux Universitaires Paris Seine-Saint-Denis, Hôpital Avicenne, Université Sorbonne Paris Nord, Faculté de Médecine SMBH, Bobigny, France.

Article Synopsis
  • Recent studies show that using stented cryopreserved aortic allografts for tracheobronchial replacement is effective, especially for patients with severe tracheal cancer.
  • The study analyzed 13 patients with extensive tracheal cancer from a larger registry, focusing on their surgical outcomes and complications.
  • Findings indicate that the procedure had no 30-day mortality, a high rate of complete resection, and 84.6% of patients were alive at the last follow-up, although some experienced late complications.
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Mental workload (MWL) is a concept that is used as a reference for assessing the mental cost of activities. In recent times, challenges related to user experience are determining the expected MWL value for a given activity and real-time adaptation of task complexity level to achieve or maintain desired MWL. As a consequence, it is important to have at least one task that can reliably predict the MWL level associated with a given complexity level.

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Background: Extradural disconnection of the cavernous sinus (CS) with preservation of the internal carotid artery (ICA) is indicated for aggressive and recurrent tumors, in patients presenting loss of oculomotor function and non-functional circle of Willis.

Method: Extradural resection of the anterior clinoid process disconnects the CS anteriorly. The ICA is dissected in the foramen lacerum via extradural subtemporal approach.

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Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity.

Nat Genet

April 2023

Rare Cancers Genomics Team, Genomic Epidemiology Branch, International Agency for Research on Cancer/World Health Organization, Lyon, France.

Malignant pleural mesothelioma (MPM) is an aggressive cancer with rising incidence and challenging clinical management. Through a large series of whole-genome sequencing data, integrated with transcriptomic and epigenomic data using multiomics factor analysis, we demonstrate that the current World Health Organization classification only accounts for up to 10% of interpatient molecular differences. Instead, the MESOMICS project paves the way for a morphomolecular classification of MPM based on four dimensions: ploidy, tumor cell morphology, adaptive immune response and CpG island methylator profile.

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[Revision of the French colposcopic terminology].

Gynecol Obstet Fertil Senol

May 2023

Société française de colposcopie et pathologie cervico-vaginale (SFCPCV), Paris, France; Service de chirurgie gynécologique, Centre hospitalier universitaire Nord (APHM), Aix-Marseille Université (AMU), Univ Avignon, CNRS, IRD, IMBE UMR 7263, 13397 Marseille, France. Electronic address:

Objectives: To revise the 1983 colposcopic terminology form the French Society of Colposcopy and cervicovaginal pathology (SFCPCV).

Methods: All the three following steps of colposcopic examination were considered for the description of various colposcopic features: inspection without coloration, followed by the application of acetic acid and iodine staining. This revised terminology now includes the different possible colposcopic aspects of the normal cervix, including the ectropion and the normal transformation zone.

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[Lung transplantation for lymphangioleiomyomatosis].

Rev Mal Respir

March 2023

Inserm UMR 1272, université Sorbonne Paris Nord, AP-HP, hôpital Avicenne, service de pneumologie, Bobigny, France; Service de pneumologie, hôpital Avicenne, Assistance publique-Hôpitaux de Paris, Paris, France.

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[Lung transplantation for systemic sclerosis-associated interstitial lung disease].

Rev Mal Respir

March 2023

Service de Pneumologie et Equipe de Transplantation Pulmonaire, Centre Hospitalo-Universitaire Nord, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France.

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