3 results match your criteria: "Hôpital Saint-Louis and Paris Diderot Sorbonne University[Affiliation]"

Background: Acute respiratory failure (ARF) is the leading cause of intensive care unit (ICU) admission in patients with Acute Myeloid Leukemia (AML) and data on prognostic factors affecting short-term outcome are needed.

Methods: This is a post-hoc analysis of a multicenter, international prospective cohort study on immunocompromised patients with ARF admitted to ICU. We evaluated hospital mortality and associated risk factors in patients with AML and ARF; secondly, we aimed to define specific subgroups within our study population through a cluster analysis.

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End of life decisions in immunocompromised patients with acute respiratory failure.

J Crit Care

December 2022

Department of Anesthesia and Intensive Care unit, Regional University Hospital of Montpellier, St-Eloi Hospital, University of Montpellier, Phymedexp, Université de Montpellier, Inserm, CNRS, CHRU de Montpellier, Montpellier, France. Electronic address:

Article Synopsis
  • The study investigates factors that influence the decision to forgo life-sustaining therapies (DFLSTs) in critically ill immunocompromised patients with acute respiratory failure admitted to the ICU.
  • It is based on data from a large international study that included 1,611 patients across 68 ICUs in 16 countries, analyzing patient, disease, and organizational factors through multivariate logistic analysis.
  • Key findings reveal that about 28% of patients had DFLSTs, with significant associations found with older age, poor performance status, certain disease complications, and the involvement of a pulmonologist in care, suggesting better outcomes with specialist involvement.
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Article Synopsis
  • Scientists studied how influenza affects very sick patients in intensive care units (ICUs) who have weak immune systems.
  • They found that patients with influenza had a higher chance of needing help to breathe and stayed longer in the ICU compared to those without it.
  • However, the type of infection didn't seem to change the overall chance of dying in the hospital.
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