A Retrospective Study of Ultrasound-guided Hydrodilatation of Glenohumeral Joint Combined with Corticosteroid Injection in Patients with Frozen Shoulder.

Objective The purpose of this study was to establish the efficacy of ultrasound (US)-guided hydrodilatation of the glenohumeral joint, in conjunction with corticosteroid injection, in alleviating pain and improving shoulder joint adhesion among patients with primary frozen shoulder (FS). Background: FS, also known as adhesive capsulitis, is a pathological condition characterized by pain and potential functional impairment. The natural progression of FS involves three distinct stages: freezing, frozen, and thawing.

Investigate mothers' perceptions and experiences of natural childbirth and quality of care in childbirth management based on Safe Childbirth Checklist: A qualitative study.

Background: The Safe Childbirth Checklist (SCC) was designed in an effort to support health workers to perform essential tasks and improve the quality of care (QoC) for mothers and babies during childbirth. Given the fact that human experiences in any society can be influenced by cultural, economic, and social differences. Therefore, the present qualitative study aimed to investigate mothers' perceptions and experiences of natural childbirth and QoC in childbirth management based on SCC.

Broad ligament ectopic pregnancy with full-term live birth: a rare case report from Syria.

Ectopic pregnancy, the implantation of a fertilized zygote outside the uterine cavity, presents with abdominal pain and vaginal bleeding. Diagnosis relies on clinical signs, and treatment involves surgery or methotrexate in selected cases. A 24-year-old woman at 37 weeks of gestation underwent elective cesarean delivery under general anesthesia, revealing an unexpected broad ligament ectopic pregnancy.

Cannabidiol promotes apoptosis and downregulation of oncogenic factors.

Patients with high-grade serous carcinoma of tubo-ovarian origin (HGSC) often experience significant side effects related to their disease and treatments, such as pain, discomfort, nausea, and vomiting. Over the last two decades, the use of cannabinoids (CBD) to manage pain and anxiety has become more mainstream. However, there is limited data on how CBD interacts with HGSC tumor cells or whether CBD impacts the effect of chemotherapy.

Mixed Ovarian Carcinoma Comprising Clear Cell Carcinoma and Endometrioid Carcinoma: A Case Report.

We present a unique case of mixed ovarian carcinoma, including both clear cell carcinoma (CCC) and grade 1 endometrioid carcinoma (EC) in a 49-year-old woman. The patient had no complaints of pain but presented with an enlarged abdomen, necessitating a thorough diagnostic assessment. Histopathological evaluation revealed an unusual histological juxtaposition of CCC coexisting with grade 1 EC found in an ovarian mass, resulting in diagnostic and therapeutic challenges.

Risk Prediction Models as an Emerging Trend for Managing Cancer-Related Fatigue: A Systematic Review.

Aim: To systematically identify, describe and evaluate the existing risk prediction models for cancer-related fatigue.

Design: Systematic review.

Data Sources: Seven databases (EMBASE, Cochrane Database, MEDLINE, CINAHL, CNKI, SinoMed and Wanfang) were conducted from inception to August 14, 2023 and updated in September 15, 2024.

Topical high concentration oxygen with hyaluronic acid: A safe and effective treatment for vaginal atrophy and sexual function improvement.

Background: Genitourinary syndrome of menopause (GSM) is a condition affecting many postmenopausal women. Among the available treatments, the vaginal natural oxygenation device (VNOD) is a new promising option.

Aim: To evaluate the safety and the effectiveness of vaginal high concentration (HC) oxygen (O) and hyaluronic acid (HA) in postmenopausal women with vaginal atrophy (VA).

Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series.

Renal angiomyolipomas, benign tumors composed of blood vessels, adipose tissue, and smooth muscle, affect approximately 70% to 80% of patients with tuberous sclerosis. Angiomyolipomas smaller than 4 cm are usually asymptomatic, whereas larger ones can cause lumbar pain, anemia, and hematuria. Contrary to its sporadic counterparts, tuberous sclerosis-associated angiomyolipomas often present at a young age, are multicentric and large, and carry a higher risk of life-threatening hemorrhage.

Dilapan-S versus Standard Methods for Cervical Ripening in Term Pregnancies: An Individual Patient Data Meta-Analysis.

Objectives: Dilapan-S is a cervical ripening agent approved by the FDA that has been found to be just as effective as other agents and can be utilized for outpatient ripening. No large-scale studies have been conducted to compare cesarean delivery rates between Dilapan-S and other ripening methods. Our objective was to combine these trials to compare cesarean delivery rates for Dilapan-S with other cervical ripening methods, overall and in sub-groups.

Mesalamine as treatment of neovaginal ileitis: Case report and review of literature.

Background: Neovaginal ileitis is an understudied complication of intestinal vaginoplasty for which no evidence-based treatments exist. Mesalamine has been successfully reported to treat neovaginal colitis and has mixed evidence of efficacy in treating ileal inflammatory syndromes.

Case: We report a 29-year-old female with a history of ileal neovaginoplasty at two years of age for cloacal variant and treatment-refractory neovaginal ileitis with pain and bleeding whose symptoms resolved with treatment with topical mesalamine.

Influence of COVID-19 Vaccination Covaxin on Menstrual Cycle among Adolescent Healthy Schoolgirls in South India.

This study was undertaken to assess the change in menstrual cycle interval, duration, amount of flow, and new onset of pain after the first and second dose of Covaxin vaccination among adolescent schoolgirls aged 15-18. Informed assent and parental consent were taken. Two hundred and thirty-three participants were approached and the response rate was 57.

Iatrogenic Budd-chiari Syndrome from Misplacement of Right Internal Jugular Central Vein Catheter: A Case Report.

Introduction/background: Budd-Chiari syndrome is a rare entity that is caused by an obstruction of the flow in the hepatic veins or inferior vena cava.

Case Presentation: Herein, we report a rare case of iatrogenic Budd-Chiari syndrome. A 52-year-old woman with chronic renal failure under hemodialysis, presented to our hospital for dyspnea caused by a large pleural effusion.

Uterine fibroids show evidence of shared genetic architecture with blood pressure traits.

Uterine leiomyomata (fibroids, UFs) are common, benign tumors in females, having an estimated prevalence of up to 80%. They are fibrous masses growing within the myometrium leading to chronic symptoms like dysmenorrhea, abnormal uterine bleeding, anemia, severe pelvic pain, and infertility. Hypertension (HTN) is a common risk factor for UFs, though less prevalent in premenopausal individuals.

Intersecting Pathologies: Vulvar Cancer Complicated by a Fusobacterium necrophorum Infection.

Vulvar cancer represents a small minority of annual cancer cases in America. This malignancy affects more than the physical health of the patient. This malignancy also has a negative impact on women's psychological and sexual health.

Acellular Appendix Vermiform Mucinous Neoplasm.

Appendiceal neoplasms are usually asymptomatic or associated with mild, nonspecific symptoms. Due to the rarity of the disease and the lack of specific symptoms, this clinical entity escapes the diagnostic consideration of the gynecologist, when women come in with right iliac fossa pain. A case is presented of a 56-year-old woman with a mass in the right small pelvis, which was preoperatively diagnosed as originating from the ovary.

An Unusual Case of Pelvic Congestion Syndrome: A Case Report.

This manuscript presents a case of a 35-year-old nulligravida premenopausal woman who presented with acute abdominal pain due to pelvic congestion syndrome (PCS). PCS is characterized by multiple pathophysiological mechanisms and various clinical presentations. Our patient was nulliparous with no history of abdominal surgery.

Exploring Self-Reported Symptoms for Developing and Evaluating Digital Symptom Checkers for Polycystic Ovarian Syndrome, Endometriosis, and Uterine Fibroids: Exploratory Survey Study.

Background: Reproductive health conditions such as polycystic ovary syndrome (PCOS), endometriosis, and uterine fibroids pose a significant burden to people who menstruate, health care systems, and economies. Despite clinical guidelines for each condition, prolonged delays in diagnosis are commonplace, resulting in an increase to health care costs and risk of health complications. Symptom checker apps have the potential to significantly reduce time to diagnosis by providing users with health information and tools to better understand their symptoms.

The oral GnRH antagonists, a new class of drugs in gynecology: from pharmacokinetics to possible clinical applications.

Introduction: In ovarian steroid-dependent diseases such as uterine fibroids, endometriosis and adenomyosis, oral GnRH antagonists have emerged as new therapeutic alternatives. These oral GnRH antagonists offer key advantages, including oral administration, dose-dependent estrogen suppression and rapid reversibility.

Areas Covered: This review examines the pharmacological, clinical and therapeutic profiles of the latest non-peptide oral GnRH antagonists, through an analysis of clinical evidence and randomized clinical trials, to provide a comprehensive and up-to-date overview of their clinical applications and potential benefits.

Axillary Surgery in Breast Cancer - Primary Results of the INSEMA Trial.

Background: Whether surgical axillary staging as part of breast-conserving therapy can be omitted without compromising survival has remained unclear.

Methods: In this prospective, randomized, noninferiority trial, we investigated the omission of axillary surgery as compared with sentinel-lymph-node biopsy in patients with clinically node-negative invasive breast cancer staged as T1 or T2 (tumor size, ≤5 cm) who were scheduled to undergo breast-conserving surgery. We report here the per-protocol analysis of invasive disease-free survival (the primary efficacy outcome).

Postoperative analgesic effect of intravenous coinjection of lidocaine and dexmedetomidine in gynaecological surgery: a systematic review and meta-analysis.

Objectives: Hysterectomy or myomectomy is a common gynaecological procedure that results in moderate to severe acute postoperative pain, which can cause many adverse effects. This study aimed to compare the postoperative analgesic efficacy, opioid consumption, quality of postoperative recovery (QOR) and adverse reactions of intravenous coinjection of lidocaine and dexmedetomidine versus lidocaine or dexmedetomidine alone in gynaecological surgery.

Design: Systematic review and meta-analysis was performed.

Successful Microablative Fractional Carbon Dioxide Laser Therapy for Vulvar Lichen Sclerosus: A Case Report and Mini-review.

Vulvar lichen sclerosus (VLS) is a chronic inflammatory skin disorder affecting the vulvar region. VLS predominantly affects women, and most cases occur after menopause. Common symptoms include itching, skin-whitening, pain, discomfort, fissures, and scarring.

Body Mass Index and Surgical Diagnosis of Endometriosis: Do Obese Patients Experience an Operative Delay?

Objectives: The objective of this study was to quantify the time to diagnosis of endometriosis by laparoscopy for patients of varying body mass index (BMI), as well as the safety of laparoscopy for endometriosis by BMI.

Materials And Methods: We performed a retrospective cohort study of reproductive-age women receiving a primary laparoscopic diagnosis of endometriosis at an academic tertiary hospital from January 2017 to December 2020. Patients excluded were those undergoing repeat laparoscopy, with previously histologically diagnosed endometriosis, asymptomatic endometriosis, an unknown first gynecologic encounter, or an unknown initial BMI.