Sea Hare Hydrolysate Reduces PD-L1 Levels in Cancer Cells and Mitigates Rheumatoid Arthritis Ina Collagen-Induced Arthritis Mouse Model.

Our previous study highlighted the anticancer potential of sea hare hydrolysate (SHH), particularly its role in regulating macrophage polarization and inducing pyroptotic death in lung cancer cells through the inhibition of signal transducer and activator of transcription 3 (STAT3). These findings prompted us to investigate additional features of immune-oncology (I-O) agents or adjuvants, such as programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) inhibition and their association with rheumatoid arthritis (RA) risk, to explore the potential of SHH as an I-O agent or adjuvant. In this study, we investigated the effects of SHH on PD-L1 levels in various cancer cell types and assessed its effectiveness in treating RA, a common side effect of I-O agents.

Exploring the role of grafting in abiotic stress management: Contemporary insights and automation trends.

Grafting is a technique that involves attaching a rootstock to the aerial part of another genotype or species (scion), leading to improved crop performance and sustainable growth. The ability to tolerate abiotic stresses depends on cell membrane stability, a reduction in electrolyte leakage, and the species of scion and rootstock chosen. This external mechanism, grafting, serves as a beneficial tool in influencing crop performance by combining nutrient uptake and translocation to shoots, promoting sustainable plant growth, and enhancing the potential yield of both fruit and vegetable crops.

Correction: Ion pair extractant selective for LiCl and LiBr.

[This corrects the article DOI: 10.1039/D4SC03760J.].

Effects of simultaneous intake of dietary fermented foods and processed meat products on the risk of colorectal cancer.

This study investigated the effects of fermented food consumption on the risk of colorectal cancer (CRC) related to processed meat intake using a mouse model. Processed meat products and fermented foods were supplemented to analyze heterocyclic amines (HCA) and carcinoembryonic antigen (CEA) levels and the gut microbiota in mice. The study determined age to be a non-influential factor.

β-Sitosterol-Dietary sources and role in cancer and diabetes management.

β-Sitosterol is a major bioactive constituent and the most abundant phytosterol in nuts, seeds, and vegetable oils. It is structurally similar to cholesterol, except for the addition of the ethyl group. The primary benefit of β-sitosterol is that it lowers the body's absorption of low-density lipoprotein, or "bad" cholesterol.

Anti-Inflammatory Effects of Fermented and Aged Mountain-Cultivated Ginseng Sprouts via Suppression of MAPK-NF-κB Pathway in Lipopolysaccharide-Stimulated RAW264.7 Macrophages.

Fermented and aged mountain-cultivated ginseng sprouts (FAMCGS) exhibit superior antioxidant and anti-inflammatory properties compared to mountain-cultivated ginseng sprouts (MCGS). However, the mechanisms behind these properties of FAMCGSE remain unclear. This study explores the anti-inflammatory effects of FAMCGS extract (FAMCGSE) on LPS-stimulated RAW 264.

Pathway control in metallosupramolecular polymerization of a monoalkynylplatinum(ii) terpyridine complex through competitive complex formation.

Understanding the pathway complexity of supramolecular polymerization in biomimetic systems has been a challenging issue due to its importance in the development of rationally controlled materials and insight into self-assembly in nature. We herein report a kinetic trapping strategy as a new methodology on how to control the pathway of metallosupramolecular polymerization by employing secondary metal ions and/or ligands which form competitive complex species. For this, we proposed monoalkynylplatinum(ii) metalloligand (Pt-L) derived from a bis(amideterpyridine) receptor with one unoccupied terpyridyl terminal as a coordination site for the secondary metal ion (Ag or Fe).

First record of Huang & Ding (Hemiptera, Delphacidae, Delphacinae) from South Korea, with an illustrated key to the Korean Tropidocephalini species.

Background: The tribe Tropidocephalini is the second largest tribe of the subfamily Delphacinae, comprising 204 species of 37 genera worldwide. Most species in this tribe feed on bamboo (Bambusoideae) or grasses (Poaceae). In Korea, only three species have been reported.

Review of the Palaearctic species of Bouček, 1956 (Chalcidoidea, Pteromalidae), with descriptions of the eight new species.

Palaearctic species of the genus Bouček, 1956 are reviewed. Twelve Palaearctic species are recognized based on females, of which eight new species are described: Tselikh, Lee & Ku, (Republic of Korea), Tselikh, Lee & Ku, (Republic of Korea), Tselikh, Haas & Ku, (Republic of Korea, Sweden), Tselikh, Lee & Ku, (Republic of Korea), Tselikh, Lee & Ku, (Republic of Korea), Tselikh, Lee & Ku, (Republic of Korea), Tselikh, Haas & Ku, (Germany, Japan, Sweden), and Tselikh, Haas & Ku, (Russia, Republic of Korea, Sweden). The female of Bouček, 1956 is described for the first time.

Development of eco-friendly pretreatment processes for high-purity silicon recovery from end-of-life photovoltaic modules.

This study examines the efficacy of photovoltaic (PV) recycling processes and technologies for the recovery of high-purity silicon powder from waste solar modules. In order to facilitate the simplification of complex processes, such as the conventional nitric acid dissolution, solvent and ultrasonic irradiation, and solvent dissolution, a variety of mechanical separation processes have been established. These processes are designed to enhance the efficiency and effectiveness of the aforementioned processes.

Surface engineering of high- polymeric dielectric layers with a fluorinated organic crosslinker for use in flexible-platform electronics.

High- polymeric layers were prepared by combining various functional groups and were applied as gate dielectrics for practical organic field-effect transistors (OFETs). Crosslinking of the polymeric layers through UV-assisted organic azide fluorine-based crosslinkers induced dramatic improvements in the electrical performance of the OFET, such as field-effect mobility and bias-stress stability. Our synthesis and manufacturing method can be a useful technique for ensuring device operation stability and electrical property enhancement.

Improving reconstructions in nanotomography for homogeneous materials mathematical optimization.

Compressed sensing is an image reconstruction technique to achieve high-quality results from limited amount of data. In order to achieve this, it utilizes prior knowledge about the samples that shall be reconstructed. Focusing on image reconstruction in nanotomography, this work proposes enhancements by including additional problem-specific knowledge.

Slow vibrational relaxation drives ultrafast formation of photoexcited polaron pair states in glycolated conjugated polymers.

Glycol sidechains are often used to enhance the performance of organic photoconversion and electrochemical devices. Herein, we study their effects on electronic states and electronic properties. We find that polymer glycolation not only induces more disordered packing, but also results in a higher reorganisation energy due to more localised π-electron density.

Overcoming copper-induced conversion reactions in nickel disulphide anodes for sodium-ion batteries.

Employing copper (Cu) as an anode current collector for metal sulphides is perceived as a general strategy to achieve stable cycle performance in sodium-ion batteries, despite the compatibility of the aluminium current collector with sodium at low voltages. The capacity retention is attributed to the formation of copper sulphide with the slow corrosion of the current collector during cycling which is not ideal. Conventional reports on metal sulphides demonstrate excellent electrochemical performances using excessive carbon coatings/additives, reducing the overall energy density of the cells and making it difficult to understand the underlying side reaction with Cu.

Controlling supramolecular copolymerization of alkynylplatinum(ii) terpyridine complexes: from isodesmic to cooperative mechanisms.

Recently, cooperative supramolecular polymerization has garnered considerable attention due to its significant potential for enabling controlled chain-growth polymerization, which offers a route to achieving a well-defined degree of polymerization and low polydispersity. In this study, we synthesized two distinct alkynylplatinum(ii) complexes, one bearing a saturated long alkyl chain (Pt-Sat-C18) and another containing a diacetylene moiety within a long alkyl chain (Pt-DA-C25). Spectroscopic analyses revealed that Pt-Sat-C18 undergoes supramolecular polymerization an isodesmic pathway, while Pt-DA-C25 assembles cooperatively.

Synthesis and electrochemical evaluation of nickel hydroxide nanosheets with phase transition to nickel oxide.

Transition metal hydroxides are commonly used to develop nanostructures with desired functionalities by controlling their size, morphology, and structure. In this study, nickel hydroxide nanosheets with a hexagonal island shape are synthesized a surfactant-assisted method. Using this method, nickel hydroxide nanosheets can be easily achieved in a quick manner.

Co-treatment with the seed of L. and the aerial part of synergistically suppresses Aβ-induced neurotoxicity by altering APP processing.

Accumulation of β-amyloid peptide (Aβ) induces neurotoxicity, which is the primary risk factor in the pathogenesis of Alzheimer's disease (AD). The cleavage of amyloid precursor protein (APP) by the β- (BACE) and γ- (PS1, PS2) secretases is a critical step in the amyloidogenic pathway. The induction of neuronal apoptosis by Aβ involves increased expression of B-cell lymphoma protein 2 (Bcl-2)-associated X (Bax) and decreased Bcl-2 expression.

A taxonomic study of four rare pteromalid genera: Huang & Tong, Xiao & Ye, Hedqvist and Ferrière from the Eastern Palaearctic (Chalcidoidea, Pteromalidae, Pachyneurinae).

The four morphologically similar genera Huang & Tong, 1993, Xiao & Ye, 2015, Hedqvist, 1973 and Ferrière, 1934 from the Eastern Palaearctic are reviewed. Redescriptions of genera and all available types of Eastern Palaearctic species are provided. An identification key to genera is given.

Fabrication and characterization of glucose-oxidase-trehalase electrode based on nanomaterial-coated carbon paper.

Multienzyme systems are essential for utilizing di-, oligo-, and polysaccharides as fuels in enzymatic fuel cells effectively. However, the transfer of electrons generated by one enzymatic reaction in a multienzyme cascade at the electrode may be impeded by other enzymes, potentially hindering the overall efficiency. In this study, carbon paper was first modified by incorporating single-walled carbon nanotubes (SWCNTs) and gold nanoparticles (AuNPs) sequentially.

A new record of the genus Leonardi (Hemiptera, Coccomorpha, Diaspididae) in South Korea.

Background: The genus Leonardi, 1900 belongs to the family Diaspididae, and five species of have been recorded worldwide. In this study, (Green, 1905), which attacks bamboos, is newly recorded in South Korea. The colonies of were collected on a bamboo forest located in Gajwa-dong, Jinju-si, Gyeongsangnam-do, South Korea (35.

Synergistic effect of bimetallic Pd-Pt nanocrystals for highly efficient methanol oxidation electrocatalysts.

Metal nanocrystals (NCs) with controlled compositional and distributional structures have gained increasing attention due to their unique properties and broad applications, particularly in fuel cell systems. However, despite the significant importance of composition in metal NCs and their electrocatalytic behavior, comprehensive investigations into the relationship between atomic distribution and electrocatalytic activity remain scarce. In this study, we present the development of four types of nanocubes with similar sizes and controlled compositions (Pd-Pt alloy, Pd@Pt core-shell, Pd, and Pt) to investigate their influence on electrocatalytic performance for methanol oxidation reaction (MOR).