Tinzaparin use in pregnancy: an international, retrospective study of the safety and efficacy profile.

Objectives: This study audited pregnancies where the mother received tinzaparin (at any stage before delivery), with a primary objective of determining the maternal safety of this low molecular weight heparin when administered as treatment and/or prophylaxis; the secondary objective was to audit fetal and neonatal safety in this cohort. Efficacy outcomes were also recorded.

Study Design: The audit period was 1996-2009; consecutive, retrospective pregnancy records at participating hospitals were reviewed.