A finite source retrial queueing inventory system with stock dependent arrival and heterogeneous servers.

This article discusses a finite-source stock-dependent stochastic inventory system with multiple servers and a retrial facility. The system can store a maximum of S items, and the lifetime of each item is exponentially distributed. The primary customer arrives at the waiting hall from the finite source and receives service from multi-servers.

Exploring the therapeutic potential of extract: molecular docking, dynamics, and ADMET properties for cancer treatment and anti-inflammatory activity.

Colorectal cancer remains a global health challenge, prompting the exploration of natural compounds for treatment. shows promise as a source of activity biomolecules. This study analyzed the dynamics, molecular docking and ADMET properties of the extract, highlighting interaction with inflammatory protein.

Hidden benefits of snail mucus: A natural skincare marvel.

Dear Editor, From a scientific perspective, snail mucus, or snail secretion filtrate (SSF), has emerged as a significant discovery in dermatology and regenerative medicine. Several studies on mucus composition have illuminated its features in recent years, yet much remains unexplored. High-quality snail mucus contains adequate levels of active substances (e.

Eggshells & Eggshell Membranes- A Sustainable Resource for energy storage and energy conversion applications: A critical review.

As the world strives to achieve a sustainable future, the exploration of alternative and renewable raw materials for energy storage and energy conversion has gained significant attention. A growing trend on "Waste to Energy" approach has attained prominence. Accordingly, chicken eggshells, a residual from poultry industry, have emerged as a promising candidate due to their abundant availability, low cost, and unique physical and chemical properties.

In silico elucidation for the identification of potential phytochemical against ACE-II inhibitors.

Context: The present study aims to investigate the therapeutic potential of phytocompounds derived from Annona reticulata leaves for the treatment of hypertension, utilizing computational methodologies. Gaining a comprehensive understanding of the molecular interactions between neophytadiene and γ-sitosterol holds significant importance in the advancement of innovative therapeutic approaches. This study aims to examine the inhibitory effects of neophytadiene and γ-sitosterol using molecular docking and dynamics simulations.

Multitargeted pharmacokinetics, molecular docking and network pharmacology-based identification of effective phytocompounds from (L.) Merr for inflammation and cancer treatment.

According to worldwide health data, cancer, and inflammatory illnesses are on the rise and are among the most common causes of death. Across the world, these types of health problems are now considered top priorities for government health organizations. Hence, this study aimed to investigate medicinal plants' potential for treating cancer and inflammatory disorders.

Bio surfactants from lactic acid bacteria: an in-depth analysis of therapeutic properties and food formulation.

Healthy humans and animals commonly harbor lactic acid bacteria (LAB) on their mucosal surfaces, which are often associated with food fermentation. These microorganisms can produce amphiphilic compounds, known as microbial surface-active agents, that exhibit remarkable emulsifying activity. However, the exact functions of these microbial surfactants within the producer cells remain unclear.

Environmental and anthropogenic impact on conservation and sustainability of marine fish diversity.

Marine fish biodiversity and conservation linked to human livelihoods along the coast were studied in 2019 using a survey and personal interviews to investigate the effects of environmental and anthropogenic issues on changes in marine fish diversity that affect sustainability. The Zoological Survey of India (ZSI) authenticated 42 finfish, 6 crabs, and 1 shrimp from three groups collected along the coastal zone. The estimated fish species diversity index revealed that alpha and beta biodiversity were more prevalent in the study zone than gamma fish diversity.

Plant-Based Natural Bioactive Compounds 2,4-Ditert-Butylphenolas: A Potential Candidates Against SARS-Cov-2019.

The novel coronavirus 2019 is spreading around the world and causing serious concern. However, there is limited information about novel coronavirus that hinders the design of effective drug. Bioactive compounds are rich source of chemo preventive ingredients.

Plant microbe based remediation approaches in dye removal: A review.

Increased industrialization demand using synthetic dyes in the newspaper, cosmetics, textiles, food, and leather industries. As a consequence, harmful chemicals from dye industries are released into water reservoirs with numerous structural components of synthetic dyes, which are hazardous to the ecosystem, plants and humans. The discharge of synthetic dye into various aquatic environments has a detrimental effect on the balance and integrity of ecological systems.

Immobilization of Halomonas halodurans and Bacillus halodurans in packed bed bioreactor for continuous removal of phenolic impurities in waste water.

Phenol is an organic contaminant widely distributed in wastewater. Biodegradation is one of the suitable methods used to remove phenol from the wastewater. In this study, the bacterial laccase and pectinase were analyzed and phenol degradation potential was studied.

Fabrication, Characterization, and Evaluation of Eggshells as a Carrier for Sustainable Slow-Release Multi-Nutrient Fertilizers.

Development of environment-friendly fertilizers to adhere to the sustainability in agronomic practices and to overcome the limitations posed by the conventional fertilizers has been an important challenge. In this study, a cost-effective biowaste eggshell (ES) material was utilized as a sustainable support for eco-friendly slow-release multi-nutrient fertilizers (SMFs) by simple impregnation of micro- and macronutrients. The synthesized multi-nutrient composite was characterized by various characterization techniques.

Biocatalytic degradation of organophosphate pesticide from the wastewater and hydrolytic enzyme properties of consortium isolated from the pesticide contaminated water.

The indiscriminate application of various pesticides leads to toxicity to the humans, animals, fishes and threatens the environment and ecosystem. The present study was aimed to investigate pesticide degrading bacteria from the pesticide contaminated sample and to localize organophophate hydrolase activity from the bacteria. Sediment sample was selected as the source of microorganism for the degradation of chlorpyrifos.

Effective removal of pharmaceutical impurities and nutrients using biocatalyst from the municipal wastewater with moving bed packed reactor.

The presence of antibiotics in the wastewater is one of the important issues related to environmental management. In this study, antibiotics-degrading bacteria were screened from the enriched sewage sludge sample. Among the isolated bacterial strains, Bacillus subtilis AQ03 showed maximum antibiotic tolerance (>2000 ppm).

In silico, theoretical biointerface analysis and in vitro kinetic analysis of amine compounds interaction with acetylcholinesterase and butyrylcholinesterase.

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are considered important target for drug design against Alzheimer's disease. In the present study in silico analysis; theoretical analysis of biointerface between ligand and interacting amino acid residues of proteins; and in vitro analysis of enzyme inhibition kinetics were carried out to delineate the inhibitory property of amine compounds against AChE/BChE. High throughput virtual screening of amine compounds identified three compounds (2-aminoquinoline, 2-aminobenzimidazole and 2-amino-1-methylbenzimidazole) that best interacted with AChE/BChE.

Binding studies of known molecules with acetylcholinesterase and bovine serum albumin: A comparative view.

The interactions between selected molecules (piperine, tacrine, curcumin and silibinin) and proteins (acetylcholinesterase and bovine serum albumin) were investigated by Fluorescence spectroscopy, molecular docking, molecular dynamics, free energy calculation and non-covalent interaction analysis. These binding characteristics are of huge interest for understanding pharmacokinetic mechanism of the target molecules. The steady-state emission spectrum results showed that presence of static quenching mode for piperine, tacrine, curcumin, silibinin molecules with BSA and AChE complexes separately and this excitation-emission matrix analysis suggest that formation of ground-state complex between piperine, tacrine, curcumin, silibinin drugs and both BSA, AChE protein molecules.

Facile synthesis of Silver@Eggshell nanocomposite: A heterogeneous catalyst for the removal of heavy metal ions, toxic dyes and microbial contaminants from water.

In this work, silver nanoparticles have been synthesized with an average particle size of 35 nm, within 90s, using microwave and Sapindus mukorossi extract as a stabilizing agent. The AgNps were surface immobilized on eggshells (ES) to obtain Ag@ES, which was characterized by UV-Vis, UV-DRS, FT-IR, ICP-OES, TGA-DSC, SEM-EDX, XRD and XPS. Its applicability as an environmental catalyst was evaluated by Cr (VI) adsorption, photocatalytic degradation of methyl orange, eriochrome black-T, methylene blue, rhodamine-B as model dyes and microbial inhibition against Staphylococcus aureus, Escherichia coli and Candida albicans.

White Eggshells: A Potential Biowaste Material for Synergetic Adsorption and Naked-Eye Colorimetric Detection of Heavy Metal Ions from Aqueous Solution.

In the present work, we have utilized a simple, no-cost, unmodified eggshell powder as a naked-eye colorimetric detector, which on simple dispersion in aqueous solution of metal ions exhibited characteristic color change from white to pale green, pale blue, yellow, pale yellow, dark yellow, pale pink, blue, and brown for metal ions V, Cr, Cr, Fe, Fe, Co, Cu, and Ag, respectively. The effects of various parameters like concentration of metal ions, pH, temperature, and adsorbent dosage were investigated by batch sorption experiments. Also, Freundlich and Langmuir models were used to describe the adsorption isotherm.