Synthesis and characterization of zinc oxide nanocomposite for fluoride ion removal from aqueous solution.

In India, the problem of fluorosis has arisen in semi-urban and rural areas due to the intake of groundwater. The development and application of zinc oxide nanocomposite recently received a lot of attention for fluoride ion removal. Nanotechnology and nanocomposites are widely used by researchers to treat wastewater and control water pollution.

Antimicrobial, antibiofilm, docking, DFT and molecular dynamics studies on click-derived isatin-thiosemicarbazone-1,2,3-triazoles.

In an effort to develop new antimicrobial and antibiofilm agents, we have designed and synthesized a novel class of isatin-thiosemicarbazone-1,2,3-triazoles through the CuAAC approach. All the synthesized hybrids were characterized by several spectral techniques such as FTIR, H NMR, C NMR, 2D NMR and HRMS. All the derivatives were evaluated for their antimicrobial and antibiofilm efficacy towards various microbial species.

Unveiling the microbial diversity and functional dynamics of Shiv Kund, Sohna hot spring, India through a shotgun metagenomics approach.

In this research, we examined the microbial diversity in Sohna hot spring, Haryana, India using shotgun metagenome sequencing based on the Illumina Hiseq 4000 sequencing technology. The raw sequence data from metagenomic paired-end libraries were analysed for taxonomic classification, diversity, and functional annotation using MG-RAST online server. The results showed the presence of total of 57 phyla, 931 genera, and 2068 species, predominantly occupied by Moraxellaceae (Gammaproteobacteria).

Nanotechnology based technological development in biofuel production: Current status and future prospects.

Depleting fossil fuels and net carbon emissions associated with their burning have driven the need to find alternative energy sources. Biofuels are near-perfect candidates for alternative energy sources as they are renewable and account for no net CO emissions. However, biofuel production must overcome various challenges to compete with conventional fuels.

Extremophiles: the species that evolve and survive under hostile conditions.

Extremophiles possess unique cellular and molecular mechanisms to assist, tolerate, and sustain their lives in extreme habitats. These habitats are dominated by one or more extreme physical or chemical parameters that shape existing microbial communities and their cellular and genomic features. The diversity of extremophiles reflects a long list of adaptations over millions of years.

Mannose-Functionalized Isoniazid-Loaded Nanostructured Lipid Carriers for Pulmonary Delivery: In Vitro Prospects and In Vivo Therapeutic Efficacy Assessment.

Resistance to isoniazid (INH) is common and increases the possibility of acquiring multidrug-resistant tuberculosis. For this study, isoniazid-loaded nanostructured lipid carriers (INH-NLCs) were developed and effectively functionalized with mannose (Man) to enhance the residence time of the drug within the lungs via specific delivery and increase the therapeutic efficacy of the formulation. The mannose-functionalized isoniazid-loaded nanostructured lipid carrier (Man-INH-NLC) formulation was evaluated with respect to various formulation parameters, namely, encapsulation efficiency (EE), drug loading (DL), average particle size (PS), zeta potential (ZP), polydispersity index (PDI), in vitro drug release (DR), and release kinetics.

Sustainable approach for adsorptive removal of cationic and anionic dyes by titanium oxide nanoparticles synthesized biogenically using algal extract of.

Worldwide, dyes are significant pollutants present in water because of their huge consumption for industrial purposes. These dyes as pollutants cause serious health issues in human beings and cause the loss of aquatic biodiversity. So, remediation of pollutants like dyes from wastewater is the need of the hour.

Very high particulate pollution over northwest India captured by a high-density in situ sensor network.

Exposure to particulate matter less than 2.5 µm in diameter (PM) is a cause of concern in cities and major emission regions of northern India. An intensive field campaign involving the states of Punjab, Haryana and Delhi national capital region (NCR) was conducted in 2022 using 29 Compact and Useful PM Instrument with Gas sensors (CUPI-Gs).

Chitosan-Based Composites: Development and Perspective in Food Preservation and Biomedical Applications.

Chitin, which may be the second-most common polymer after cellulose, is the raw material of chitosan. Chitosan has been infused with various plant extracts and subsidiary polymers to improve its biological and physiological properties. Chitosan's physicochemical properties are enhanced by blending, making them potential candidates that can be utilized in multifunctional areas, including food processing, nutraceuticals, food quality monitoring, food packaging, and storage.

Click synthesis, antimicrobial, DNA photocleavage and computational studies of oxindole-tethered 1-1,2,3-triazoles.

To obtain new hybrids derived from isatin and triazole. A series of oxindole-1--1,2,3-triazole hybrids () were synthesized from 3-sulfenylated -propargylated oxindoles and organic azides employing Cu(I)-catalyzed azide-alkyne cycloaddition. These compounds were evaluated for antimicrobial activity by the standard serial dilution method and DNA photocleavage activity.

End fire linear antenna array synthesis using differential evolution inspired Adaptive Naked Mole Rat Algorithm.

Linear antenna arrays (LAAs) play a critical role in smart system communication applications such as the Internet of Things (IoT), mobile communication and beamforming. However, minimizing secondary lobes while maintaining a low beamwidth remains challenging. This study presents an enhanced synthesis methodology for LAAs using the Adaptive Naked Mole Rat Algorithm (ANMRA).

Solid Lipid Nanoparticles Embedded Hydrogels as a Promising Carrier for Retarding Irritation of Leflunomide.

Leflunomide (LEF), a disease-modifying anti-rheumatic drug, has been widely explored for its anti-inflammatory potential in skin disorders such as psoriasis and melanoma. However, its poor stability and skin irritation pose challenges for topical delivery. To surmount these issues, LEF-loaded solid lipid nanoparticles (SLNs) integrated with hydrogels have been developed in the present investigation.

Optimizing leachate treatment with titanium oxide-impregnated activated carbon (TiO@ASC) in a fixed-bed column: characterization, modeling, and prediction study.

This research focused on the application of a fixed bed column filled with immobilized titanium oxide-loaded almond shell carbon (TiO@ASC) for the treatment of leachate. The adsorption performance of synthesized TiO@ASC in fixed bed column is analyzed using adsorption experiments and modeling study. The characteristics of synthesized materials are determined by several instrumental techniques like BET, XRD, FTIR, and FESEM-EDX.

A panoramic view of technological landscape for bioethanol production from various generations of feedstocks.

Bioethanol is an appropriate alternate energy option due to its renewable, nontoxic, environmentally friendly, and carbon-neutral nature. Depending upon various feedstocks, bioethanol is classified in different various generations. First-generation ethanol created a food vs fuel problem, which was overcome by second-generation, third-generation and fourth-generation ethanol.

Adsorption potential of ionic liquid-modified ZnO nanoparticles for highly efficient removal of azo dye: detailed isotherms and kinetics.

In this study, bare and ionic liquid-modified ZnO nanoparticles have been fabricated using microwave irradiation method. The fabricated nanoparticles were characterized by different techniques, viz. XRD, FT-IR, FESEM, and UV-Visible spectroscopy, and were explored as adsorbent for effective sequestration of azo dye (Brilliant Blue R-250) from aqueous media.

Value addition of rice straw cellulose fibers as a reinforcer in packaging applications.

The potential use of agro-waste in food packaging applications is receiving remarkable attention due to its sustainable approach and biodegradable properties. As typical lignocellulosic biomass, rice straw (RS) is widely produced but is usually abandoned and burned, causing tremendous environmental concerns. The exploration of using RS as the source of biodegradable packaging materials is promising for economically converting this agricultural waste into packaging material, thereby providing a considerable solution for RS disposal and an alternative solution to synthetic plastic waste.

Hybrid descriptors-conjoint indices: a case study on imidazole-thiourea containing glutaminyl cyclase inhibitors for design of novel anti-Alzheimer's candidates.

Clinical studies show that the pyroglutamate alteration of amyloid-β (Aβ) catalysed by metalloenzyme glutaminyl cyclase results in the formation of the more neurotoxic pGlu-Aβ, and inhibition of glutaminyl cyclase can bring down the load of pGlu-Aβ in the brain and reduces Alzheimer's disease pathology with improvement in cognition. The present study involves the identification of activity-modulating structural features of 188 inhibitors of glutaminyl cyclase under the influence of index of ideality of correlation (IIC) and correlation intensity index (CII) as prediction parameters. The QSAR models developed employing IIC and CII were found to be statistically better and had better predictability than the models developed without them.

Review for Optimal Human-Gesture Design Methodology and Motion representation of Medical Images using segmentation from depth data and gesture recognition.

Human gesture recognition and motion representation has become a vital base of current intelligent human-machine interfaces because of ubiquitous and more comfortable interaction. Human-Gesture recognition chiefly deals with recognizing meaningful, expressive body movements involving physical motions of face, head, arms, fingers, hands or body. This review article presents a concise overview of optimal human-gesture and motion representation of medical images.

Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs.

Alzheimer's disease (AD), also called senile dementia, is the most common neurological disorder. Around 50 million people, mostly of advanced age, are suffering from dementia worldwide and this is expected to reach 100-130 million between 2040 and 2050. AD is characterized by impaired glutamatergic and cholinergic neurotransmission, which is associated with clinical and pathological symptoms.

Piperazine-1,2,3-triazole scaffolds: design, synthesis, anticancer and antimicrobial evaluation.

The objective of the present study is to design and synthesize diverse piperazine-1,2,3-triazole scaffolds as key pharmacophores possessing antimicrobial/anticancer activities. Twenty-four scaffolds were synthesized a click-inspired synthetic protocol and were assayed for anticancer activity using the methyl thiazolyl tetrazolium assay and for antimicrobial potency by serial dilution. Among all the tested 1,2,3-triazole scaffolds, compounds (IC: 5.

Remediation of contaminants from wastewater using algal nanoparticles via green chemistry approach: an organized review.

Bio-nanotechnology is one of the new and sound techniques that have various advantages over conventional methods of wastewater treatment. The utilization of nanomaterials like nanoparticles for wastewater treatment is emerging field of research. Both physical and chemical methods can be used for nanoparticle synthesis, but synthesis based on algae (biological method) has numerous advantages over others as it is environmentally friendly and sustainable.

Synthesis, Biological Evaluation and in Silico Studies of 3-Hydroxy-N-(2-(substituted phenyl)-4-oxothiazolidin-3-yl)-2-napthamide Derivatives.

In the present study, a series of 3-hydroxy-N-(2-(substituted phenyl)-4-oxothiazolidin-3-yl)-2-napthamide derivatives were synthesized, characterized and evaluated for theirin vitroactivity, i. e., antimicrobial, antioxidant and anti-inflammatory.

An Extensive Examination of the Warning Signs, Symptoms, Diagnosis, Available Therapies, and Prognosis for Lumpy Skin Disease.

The lumpy skin disease virus (LSDV) infects cattle and buffalo and causes lumpy skin disease (LSD). It affects the lymph nodes of the sick animals, causing them to enlarge and appear as lumps (cutaneous nodules) that are 2-5 cm in diameter on their heads, necks, limbs, udders, genitalia, and perinea. A high temperature, a sharp drop in milk supply, discharge from the eyes and nose, salivation, a loss of appetite, depression, damaged hides, and emaciation are further warning signs and symptoms.

Radon and thoron exhalation rate in the soil of Western Haryana, India.

This study reports the exhalation rates of radon and thoron from surface soil collected from 60 rural sites of district Hisar, Haryana, India. The exhalation rates of Rn (radon) and Rn (thoron) were measured by portable SMART RnDuo (AQTEK SYSTEMS) using a mass accumulation chamber which was equipped with a scintillation material-coated cell. Dose rates due to natural gamma radiations ranged from 0.