1 results match your criteria: "Gunma University Graduate School of Medicine 3-39-22 Showamachi[Affiliation]"
Novel ELISAs to measure total and phosphorylated tau in cerebrospinal fluid.
Neurosci Lett
March 2020
Department of Neurology, Dementia Research Center, Geriatrics Research Institute and Hospital, 3-26-8 Otomo-machi, Maebashi, 371-0847, Japan; Department of Social Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8216, Japan; Department of Neurobiology and Behavior, Gunma University Graduate School of Medicine 3-39-22 Showamachi, Maebashi, 371-8511, Japan.
Article Synopsis
- The study focused on measuring total tau (t-tau) and phosphorylated tau (p181tau) in cerebrospinal fluid (CSF) as biomarkers for Alzheimer's disease (AD).
- The researchers developed and tested new enzyme-linked immunosorbent assays (ELISAs) using 72 CSF samples, including those from patients with Alzheimer's and other neurodegenerative diseases.
- Results showed that their ELISA methods correlated well with existing systems and effectively detected significant increases in t-tau and p181tau levels in Alzheimer's patients, indicating their reliability for assessing these biomarkers.