1 results match your criteria: "Gulou Clinical College of Nanjing University of Chinese Medicine Nanjing 210008[Affiliation]"
[Sinomenine inhibits PDGF/PDGFR signaling pathway to reduce RA-FLS migration induced by NETs].
Zhongguo Zhong Yao Za Zhi
April 2024
Department of Rheumatology and Immunology, Gulou Clinical College of Nanjing University of Chinese Medicine Nanjing 210008, China.
This study aims to decipher the mechanism of sinomenine in inhibiting platelet-derived growth factor/platelet-derived growth factor receptor(PDGF/PDGFR) signaling pathway in rheumatoid arthritis-fibroblast-like synoviocyte(RA-FLS) migration induced by neutrophil extracellular traps(NETs). RA-FLS was isolated from the synovial tissue of 3 RA patients and cultured. NETs were extracted from the peripheral venous blood of 4 RA patients and 4 healthy control(HC).
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