811 results match your criteria: "Gulhane School Of Medicine[Affiliation]"

To demonstrate the prevalence of malnutrition risk in a specific rehabilitation setting. The secondary aim of the study was to compare Malnutrition Screening Tool (MST) and Malnutrition Universal Screening Tool (MUST) with Nutritional Risk Screening-2002 (NRS-2002). Patients diagnosed with stroke, anoxic brain injury, spinal cord injury, multiple sclerosis, arthritis, neuromuscular diseases, Parkinson's disease, and lymphedema who were admitted to a rehabilitation hospital were included.

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: Salvage treatment options have not been validated in relapsed or refractory germ cell tumors. Moreover, the study populations including these patients have different heterogeneities. This study aimed to evaluate the efficacy and safety of three cycles of TIP sequential high-dose chemotherapy in patients with testicular non-seminomatous germ cell tumors who relapsed or had a refractory course after first-line platinum-based chemotherapy.

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Background: Our aim was to determine the effect of obstructive sleep apnea syndrome (OSAS) risk on sialorrhea in patients with Parkinson's disease (PD).

Methods: A total of 75 patients with PD (mean age 66.36 ± 8.

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Background: Acute subdural hematoma (ASDH) is a critical and often fatal condition, particularly in elderly patients receiving anticoagulant therapy. With a growing global aging population, the incidence of traumatic brain injuries, including ASDH, is projected to rise, presenting significant challenges in clinical management. This study evaluates the outcomes of surgically treated ASDH in patients aged 65 years and older, comparing those who received anticoagulant therapy with those who did not.

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Background And Aims: Insulin resistance is considered the most important key mechanism in the development of nonalcoholic fatty liver disease (NAFLD). Some studies have reported that hyperinsulinemia decreases the hepatic secretion of apolipoprotein (Apo) B. Chronic hyperinsulinemia in NAFLD may be responsible for the accumulation of triglycerides in hepatocytes.

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Background: This study aimed to determine whether surgical multiple-choice questions generated by ChatGPT are comparable to those written by human experts (surgeons).

Methods: The study was conducted at a medical school and involved 112 fourth-year medical students. Based on five learning objectives in general surgery (colorectal, gastric, trauma, breast, thyroid), ChatGPT and surgeons generated five multiple-choice questions.

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Objective: Upper extremity dysfunction is frequently seen in Parkinson's disease (PD). Existing research has shown that bradykinesia, which is main symptom of PD, is primarily responsible but the combined effects of spinal posture and axial rigidity on upper extremity functions were not investigated yet. The aim of this study was to investigate upper extremity functions in patients with PD and to evaluate relationship of these with spinal posture and axial rigidity.

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Presence of microplastics in human stomachs.

Forensic Sci Int

November 2024

Institute of Marine Sciences, Middle East Technical University, Erdemli, Mersin 33731, Turkey. Electronic address:

This study presents the first definitive confirmation of microplastic presence in the human stomach, based on samples from 26 cadavers. 97 microplastic particles were extracted from stomach contents, across all 26 individuals, revealing a universal prevalence of microplastics in the cadavers. Morphological analysis of the extracted particles unveiled distinct shapes, with fibers constituting the majority (52.

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Aim: This study aimed to develop a blended training module focusing on ethical approaches within general surgery residency training and to assess the impact of this training on participants.

Methods: Based on the literature review and input from both general surgery residents and trainers, 14 topics were identified, and corresponding learning objectives were formulated. The training was conducted through a blended learning module, which encompassed online video presentations alongside face-to-face sessions involving real-life cases.

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Article Synopsis
  • * Among 106 patients, 83 had CN, and those who had the surgery could continue their nivolumab treatment for longer (14.5 months) compared to those who didn't have the surgery (6.7 months).
  • * Overall survival was better for patients with CN (22.9 months) compared to those without it (8.1 months), but the surgery and certain medical scores were important factors for how long they lived.
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Purpose: This study aimed to determine the effects of Reiki on pain and biochemical parameters in patients undergoing bone marrow transplantation.

Design: This research was a single-blind, repeated measures, randomized prospective controlled study.

Method: This study was conducted between August 2022 and April 2023 with patients who underwent autologous in the bone marrow transplantation (BMT) unit.

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Background: Home blood pressure monitoring (HBPM) is commonly used to diagnose hypertension (HT), with a diagnostic threshold of ≥135/85 mm Hg, the same as daytime ambulatory BP monitoring (ABPM). This study hypothesizes that training and adherence to HBPM guidelines will yield more accurate BP readings compared to ABPM.

Methods: The study involved 129 patients with elevated office BP but no prior HT diagnosis.

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Article Synopsis
  • Graft failure is a frequent issue in cranioplasty, necessitating revision procedures, and this study explores outcomes using custom-made 3D titanium implants for such revisions.
  • In a review of 43 patients from 2011 to 2019, those with initial polymethyl methacrylate (PMMA) implants experienced a longer duration before needing revisions compared to those with autologous grafts (AG), without significant differences in hospital stay length.
  • The findings suggest that while PMMA leads to longer timeframes before revision compared to AG, both show similar hospitalization results, and custom-made 3D titanium implants prove beneficial in reducing implant failure and addressing cosmetic issues.
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Profiles of primary brain abscesses and their impact on survival: An international ID-IRI study.

Int J Infect Dis

October 2024

Gulhane School of Medicine, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Ankara, Türkiye.

Article Synopsis
  • This study analyzed 331 patients with primary brain abscesses (PBAs) from 39 centers in 16 countries, focusing on infection causes, risk factors, and mortality outcomes over a 12-year period.
  • Study results showed that the majority of patients were middle-aged men (average age 46.8), with symptoms like headaches and fever; Gram-positive cocci were the most common pathogens.
  • Key factors influencing mortality at 42 days included intravenous drug use and malignancy, while factors affecting 180-day mortality included temporal lobe involvement and the presence of unidentified bacteria.
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Therapeutic apheresis treatment in rheumatic diseases: Insights from a single-center experience.

Ther Apher Dial

February 2025

Department of Internal Medicine, Division of Rheumatology, Gulhane Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

Introduction: We aimed to evaluate the characteristics of the patients with a rheumatologic disease who underwent TPE.

Method: A single-center, retrospective study was conducted between January 2016 and June 2023.

Results: Twenty patients with a median age of 51 years received a median of 6 TPE sessions.

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Article Synopsis
  • This study focuses on the challenges of endoscopic management of pediatric hydrocephalus, particularly due to the unique anatomical structures of children's ventricles.
  • It analyzed surgical cases from 84 children aged around 7.6 months, identifying common causes of hydrocephalus and noting significant variations and deformities in the ventricular anatomy in 83% of cases.
  • The findings emphasize the importance of understanding these anatomical variations to enhance surgical safety, as they are often not evident in preoperative imaging.
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Introduction: Data about the demographic and clinical characteristics of melanoma patients in Turkey is limited.

Objectives: Data about the demographic and clinical characteristics of melanoma patients in Turkey is limited. We aimed to review the features of patients with primary cutaneous melanoma (PCM) diagnosed and treated in a tertiary referral center.

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Background: Blood culture-negative endocarditis (BCNE) is a diagnostic challenge, therefore our objective was to pinpoint high-risk cohorts for BCNE.

Methods: The study included adult patients with definite endocarditis. Data were collected via the Infectious Diseases International Research Initiative (ID-IRI).

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Background: This study aimed to identify factors that influence the mortality rate of patients with coronavirus disease (COVID-19)-associated pulmonary aspergillosis (CAPA).

Methods: In this cross-sectional study, data from 23 centers across 15 countries, spanning the period of March 2020 to December 2021, were retrospectively collected. The study population comprised patients who developed invasive pulmonary aspergillosis while being treated for COVID-19 in the intensive care unit.

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Herein, we aimed to investigate the antifungal susceptibility pattern of Candida auris clinical strains in our setting Bahrain Oncology Center-King Hamad University Hospital-Bahrain. C. auris strains isolated from different clinical specimens in the Microbiology Laboratory from October-2021 to November-2022 were evaluated.

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Factors influencing mortality in COVID-19-associated mucormycosis: The international ID-IRI study.

Med Mycol

July 2024

Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey.

Article Synopsis
  • - The COVID-19 pandemic led to a rise in cases of mucormycosis, particularly in India, prompting a study to analyze factors affecting mortality in COVID-19-associated mucormycosis (CAM) among patients in mainly Asian and some African countries.
  • - The study included 162 CAM patients, primarily older males, with a high prevalence of diabetes and rhino-orbital-cerebral mucormycosis; results indicated a 39% mortality rate influenced by advanced age, use of rituximab, and diabetic ketoacidosis as significant risk factors.
  • - Findings suggest that surgical debridement improves survival rates, and combining antifungal treatments with surgery significantly enhances outcomes for CAM patients.
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Objective: Short-chain fatty acids (SCFAs) are produced when the microbiota in the large intestine cause fermentation of dietary carbohydrates and fibers. These fatty acids constitute the primary energy source of colon mucosa cells and have a protective effect in patients suffering from inflammatory bowel disease (IBD). This study aimed to compare the SCFA levels in the stools of patients with IBD and healthy controls.

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Background And Purpose:

Parkinson’s disease (PD) is a heterogeneous neurodegenerative disorder characterized by contradictory clinical outcomes among its several subtypes. The disease can manifest with a tremor-dominant (TD) or a non-tremor-dominant (NTD) phenotype. Although the TD subtype may show a better prognosis, there is limited information on the phenotypic differences regarding the level of axial symptoms.

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