5 results match your criteria: "Guizhou Provincial Orthopaedic Hospital[Affiliation]"
Effect of Thiopental on Ischemic Stroke in Rat Brain in Spontaneously Hypertensive Rats.
Appl Bionics Biomech
January 2022
Department of Anesthesiology, Guizhou Provincial People's Hospital, China.
. Thiopental is an anesthetic drug related to the condition of controlling the area of neurological contexts. This study is related to the analysis of effectiveness for the condition of thiopental application on spontaneously hypertensive rats.
View Article and Find Full Text PDFPropofol Alleviates Neuropathic Pain Induced by Chronic Contractile Injury by Regulating the Spinal glun2b-p38mapkepac1 Pathway.
Comput Math Methods Med
February 2022
Department of Anesthesiology, Guizhou Provincial Orthopaedic Hospital, Guizhou, China.
Background: Propofol acts as an intravenous anesthetic cure which is widely used as a therapy for the craniocerebral injury that comprised surgical anesthesia as well as the sedation done in the intensive care units. Propofol is one of the most commonly used and efficient anesthetics where the painful effects are followed by an injection of propofol. In many cases, patients experience pain followed by anxiety, boredom, fear, and even myocardial ischemia.
View Article and Find Full Text PDFMolecular Mechanism of Gas Anesthetics on the Invasion, Metastasis, and Chemosensitivity of Osteosarcoma Cells.
Comput Math Methods Med
February 2022
Department of Anesthesiology, Guizhou Provincial People's Hospital, Guizhou, China.
Article Synopsis
- Osteosarcoma is a prevalent bone cancer primarily affecting children and adolescents, and this study examines how gas anesthetics impact the behavior of osteosarcoma cells, particularly focusing on invasion, metastasis, and response to chemotherapy.
- Isoflurane and sevoflurane significantly inhibit osteosarcoma cell migration and proliferation at clinically relevant doses, while desflurane is less effective; all anesthetics enhance the effects of chemotherapeutic drugs.
- The research concludes that gas anesthetics influence the survival, movement, growth, and sensitivity to chemotherapy in osteosarcoma cells, potentially by affecting specific cellular pathways like PI3K/AKT and IGF-1.
MicroRNA-532-5p is implicated in the regulation of osteoporosis by forkhead box O1 and osteoblast differentiation.
BMC Musculoskelet Disord
May 2020
Orthopedic surgery of Wuhan General Hospital of People's Liberation Army, No.627 Wuluo Road, Wuhan City, Hubei Province, 430000, PR China.
Background: MicroRNAs (miRNAs) are critical regulators in osteogenesis and cartilage formation. This study was designed to investigate whether miR-532-5p plays a role in the regulation of osteoporosis.
Methods: Osteoporotic fractures (OP group, n = 10) or osteoarthritis without osteoporosis (control group, n = 10) were selected as subjects in this study.
Impacts of triamcinolone acetonide on femoral head chondrocytic structures in lumbosacral plexus block.
Saudi Pharm J
May 2017
Department of Critical Care Medicine, Guizhou Provincial Orthopaedic Hospital, Guiyang 550002, China.
To investigate impacts of triamcinolone acetonide (TRI) on femoral head chondrocytic (FHC) structures when used for lumbosacral plexus block (LPB). A total of 32 6-month-old New Zealand white rabbits were selected (averagely weighing 2.75-3.
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