Double cross-linked cellulose hydrogel-supported Fe species for efficient wound healing.

Traditional dressings often lack adequate skin structure support, which can lead to secondary damage, poor hemostasis, and an increased risk of inflammation due to wound adhesion. In this work, cellulose hydrogels were prepared by physical/chemical double cross-linking a 'sol-gel' strategy and further loaded with Fe to obtain a three-dimensional (3D) porous cellulose/Fe composite hydrogel (cellulose/Fe gel). The obtained cellulose/Fe gel featured a 3D porous nanofiber structure, excellent water absorption/moisture retention performance, and good mechanical stability.