LC-MS/MS-based metabolic profiling: unraveling the impact of varying degrees of curing on metabolite transformations in tobacco.

The curing process regulates metabolite transformations of leaves and significantly influences the formation of tobacco quality. This study investigated the major physicochemical compositions and metabolic profiles under normal curing (NC), excessive curing (EC), and insufficient curing (IC) treatments. The results indicated that the contents of nicotine, nitrogen, potassium, and chlorine remained stable among treatments, while the sugar content in EC was significantly lower than in IC.

Characterization of the evolution of free radicals and TALAs in linseed oil during heat treatment.

Various studies have demonstrated that employing ESR spin trapping to detect free radicals yields valuable insights into the vulnerability of bulk oils to oxidation. Consequently, this method can be employed to assess and compare the oxidative stability of different samples. This study was conducted to investigate the production and transformation of free radicals and trans isomers in linseed oil when subjected to different temperatures and durations of heating.

Exposure to heavy metal elements may significantly increase serum prostate-specific antigen levels with overdosed dietary zinc.

Background: Serum prostate-specific antigen (PSA) is a primary metric for diagnosis and prognosis of prostate cancer (PCa). Exposure to heavy metals, such as lead, cadmium, mercury, and zinc can impact PSA levels in PCa patients. However, it is unclear whether this effect also occurs in men without PCa, which may lead to the overdiagnosis of PCa.

A new species of (Amphibia, Anura, Ranidae) from Guizhou Province, China.

The Torrent frogs of the genus are widely distributed in Nepal and northern India eastwards to southern China and southwards to Malaysia. The genus currently contains 84 species. Previous studies indicated underestimated species diversity in the genus.

Description of a new Asian Leaf Litter Toad of the genus Smith, 1925 (Anura, Megophryidae) from southern Guizhou Province, China.

Background: The Asian leaf litter toads of the genus Smith, 1925 (Anura, Megophryidae) inhabit the forest floor and rocky streams in hilly evergreen forests and are widely distributed from southern China, west to north-eastern India and Myanmar, through mainland Indochina to Peninsular Malaysia and the Island of Borneo.

New Information: A new species of the Asian leaf litter toad genus from Guizhou Province, China is described. Molecular phylogenetic analyses, based on mitochondrial 16S rRNA and COI genes and nuclear RAG1 gene sequences indicated that the new species is genetically divergent from its congeners.

Study on the host-guest interactions between tetramethyl cucurbit[6]uril and 2-heterocyclic-substituted benzimidazoles.

Cucurbit[]urils (Q[]s) are a class of supramolecular host compounds with hydrophilic carbonyl ports and hydrophobic cavities, which can selectively form host-guest inclusion complexes with guest molecules to change the properties of guest molecules. In this paper, tetramethyl cucurbit[6]uril (TMeQ[6]) was used as the host and three 2-heterocyclic substituted benzimidazole derivatives as the guests, and their modes of interaction were investigated using X-ray crystallography, H NMR spectrometry, and other analytical techniques. The results showed that TMeQ[6] formed a 1 : 1 host-guest inclusion complex with three guest molecules, and the binding process between them was mainly enthalpy-driven.

Analysis of the spatial-temporal evolution of Green and low carbon utilization efficiency of agricultural land in China and its influencing factors under the goal of carbon neutralization.

Agricultural land is the most basic input factor for agricultural production and an essential component of terrestrial ecosystems, which plays a vital role in achieving carbon neutrality. Giving full play to the carbon-neutral contribution of agricultural land is a crucial part of China's economic transformation and green development. It incorporates carbon and pollution emissions from agricultural land use into the unexpected outputs of the Green and Low-carbon Utilization Efficiency of Agricultural Land (GLUEAL) evaluation system.

A fluorescent probe for detection of Hg ions constructed by tetramethyl cucurbit[6]uril and 1,2-bis(4-pyridyl)ethene.

In this paper, tetramethyl cucurbit[6]uril (TMeQ[6]) and 1,2-bis(4-pyridyl)ethene (G) were used to construct a supramolecular fluorescent probe G@TMeQ[6]. The host-guest interaction between TMeQ[6] and G was investigated using H NMR spectroscopy, single-crystal X-ray diffraction and various experimental techniques. The results show that TMeQ[6] and G form an inclusion complex with a host-guest ratio of 1:1 and the equilibrium association constant () was 2.

A new Asian leaf litter toad of the genus (Amphibia, Anura, Megophryidae) from central south China.

A new species of the Asian leaf litter toad genus from central south China is described. Molecular phylogenetic analyses, based on mitochondrial 16S rRNA and nuclear RAG1 gene sequences indicated the new species as an independent clade in the genus. The new species could be distinguished from its congeners by a combination of the following characters: body of medium size (SVL 29.

The PaO/FiO is independently associated with 28-day mortality in patients with sepsis: a retrospective analysis from MIMIC-IV database.

Background: To clarify the relationship between the PaO/FiO and 28-day mortality in patients with sepsis.

Methods: This was a retrospective cohort study regarding MIMIC-IV database. Nineteen thousand two hundred thirty-three patients with sepsis were included in the final analysis.

NHC-catalyzed [12+2] reaction of polycyclic arylaldehydes for access to indole derivatives.

An N-heterocyclic carbene (NHC) catalyzed enantio- and diastereoselective [12+2] cycloaddition is disclosed to rapidly construct sophisticated molecules bearing a tricyclic core and morpholine moiety. The success of our reaction relies on the NHC-catalyzed remote sp (C-H) bond activation of a 5-benzo[]pyrrolizine-3-carbaldehyde under oxidative conditions. Preliminary studies revealed that our products exhibit superior bioactivities against two plant pathogens to commercial Bismerthiazol (BT) and Thiodiazole Copper (TC).

Coordinated development of green finance and green technology innovation in China: from the perspective of network characteristics and prediction.

Under the path of sustainable development, the key to achieving green and low-carbon transformation lies in green technology innovation (GTI), and how to effectively coordinate the relationship between green finance (GF) and GTI is an issue worth studying. This paper constructed an evaluation system of GF and GTI and combined them with the coupled coordination degree model to explore their coordination of Chinese provinces from 2012 to 2019. Then, the core network evolution and spatial structure characteristics of GTI and GF were studied using the modified gravity model.

Coupling coordination and influencing factors of urban spatial accessibility and economic spatial pattern in the New Western Land-Sea Corridor.

The construction of the New Western Land-Sea Corridor is crucial to the economic development of western China and even Southeast Asia. Research analyzes the evolution of urban economic spatial pattern of the New Western Land-Sea Corridor in different years and discusses the coordinated development between economic connection and accessibility and its influencing factors. The research results show that: First, the influence of labor force on the urban centrality of the New Western Land-Sea Corridor is gradually increasing, and the spatial pattern of the urban network has gradually shifted from a unipolar attraction type to a spatial pattern of "one main and multiple subordinates.

Validation of the Chinese version of the physical education teacher job satisfaction scale.

Purpose: The purpose of this study was to test the factor structure as well as the reliability of the Physical Education Teacher Job Satisfaction Scale (PETJSS).

Method: The scale's structural validity, internal consistency and reliability were examined using CFA and Cronbach alpha. The predictive validity of the PETJSS was examined using Teacher Self-Efficacy (TSES-11) and the personal characteristics of the subjects.

The Spatial-Temporal Transition and Influencing Factors of Green and Low-Carbon Utilization Efficiency of Urban Land in China under the Goal of Carbon Neutralization.

Urban-land development and utilization is one of the main sources of carbon emissions. Improving the green and low-carbon utilization efficiency of urban land (GLUEUL) under the goal of carbon neutrality is crucial to the low-carbon transition and green development of China's economy. Combining the concept of green and low-carbon development in urban land use, carbon emissions and industrial-pollution emissions are incorporated into the unexpected outputs of the GLUEUL evaluation system.

Does the Urban Agglomeration Policy Reduce Energy Intensity? Evidence from China.

With the expansion of the scale of China's economy and the acceleration of urbanization, energy consumption is increasing, and environmental degradation and other problems have arisen. In order to solve such prominent problems, China proposed the "carbon peak" and "carbon neutral" targets in 2020. Although there are research conclusions about the impact of urbanization on energy intensity (), conclusions about the impact of the urban agglomeration policy () on are still unclear.

Description of a new species of the newt genus Tylototriton sensu lato (Amphibia: Urodela: Salamandridae) from southwestern China.

A new species of the genus Tylototriton sensu lato from Tongzi County, Guizhou Province, China was described. Molecular phylogenetic analyses based on mitochondrial 16S and ND2 gene sequences indicated the new species as the most closely related species of T. dabienicus in Henan.

New taxonomic framework for Arthrodermataceae: a comprehensive analysis based on their phylogenetic reconstruction, divergence time estimation, phylogenetic split network, and phylogeography.

The Arthrodermataceae, or dermatophytes, are a major family in the Onygenales and important from a public health safety perspective. Here, based on sequenced and downloaded from GenBank sequences, the evolutionary relationships of Arthrodermataceae were comprehensively studied via phylogenetic reconstruction, divergence time estimation, phylogenetic split network, and phylogeography analysis. These results showed the clades Ctenomyces, Epidermophyton, Guarromyces, Lophophyton, Microsporum, Paraphyton, and Trichophyton were all monophyletic groups, whereas Arthroderma and Nannizzia were polyphyletic.

Study on the coordination of cyclopentanocucurbit[5,6]uril with Fe, Co and Ni ions.

This paper reports the coordination of cyclopentanocucurbit[5]uril (CyPQ[5]) and cyclopentanocucurbit[6]uril (CyPQ[6]) with Fe(ClO), Co(ClO) and Ni(ClO). Single crystal X-ray diffraction analysis shows the metal ions are directly coordinated with the portal of the cucurbit[]uril to form a one-dimensional supramolecular chain or independent systems in the CyPQ[5]@Fe(ClO), CyPQ[5]@Co(ClO), CyPQ[6]@Co(ClO) and CyPQ[5]@Ni(ClO) complexes. In CyPQ[6]@Fe(ClO), the metal ion is not directly coordinated with the cucurbit[]uril portal, but after forming Fe(HO), it interacts with the cucurbit[]uril portal a hydrogen bond.

A new toad species of the genus Tian & Hu, 1983 (Anura, Megophryidae) from Guizhou Province, China.

Background: The toads of the genus Tian & Hu, 1983 are distributed in southern China, Myanmar, Vietnam, Laos and northern Thailand. Seven species of the genus have been recognised, of which five of them are known from China so far.

New Information: sp.

Data Fusion Algorithm for Myocardial Proteomics and Its Research in Sports.

Sport is a type of comprehensive activity that the human body consciously engages in to improve physical fitness. Proteomics is a comprehensive technology dedicated to the study of all protein profiles expressed by a species, individual organ, tissue, or cell under specific conditions and specific times. Proteomics is a science that studies the protein composition of cells, tissues, or organisms and their changing laws with proteomics as the research object.

Exploring the molecular mechanism of action of Polygonum capitatum Buch-Ham. ex D. Don for the treatment of bacterial prostatitis based on network pharmacology and experimental verification.

Ethnopharmacology Relevance: Polygonum capitatum Buch-Ham. ex D. Don (CNPC2009), a traditional Miao-national herbal medicine, has been widely used with considerable therapeutic efficacy in the treatment of various urologic disorders including prostatitis.