169,764 results match your criteria: "Guinea; Research and Valorization Center on Medicinal Plants Dubreka[Affiliation]"
Trends Hear
November 2024
Department of Medical Physics and Acoustics, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany.
Most neural models produce a spiking output and often represent the stochastic nature of the spike generation process via a stochastic output. Nonspiking neural models, on the other hand, predict the probability of a spike occurring in response to a stimulus. We propose a nonspiking model for an electrically stimulated auditory nerve fiber, which not only predicts the total probability of a spike occurring in response to a biphasic pulse but also the distribution of the spike time.
View Article and Find Full Text PDFNat Immunol
December 2024
Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.
Yakugaku Zasshi
November 2024
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Platelet-activating factor (PAF), a phospholipid mediator, was discovered in 1972 as an inducer of platelet aggregation. Subsequent studies have revealed that PAF has a variety of biological functions, such as its role as a potent proinflammatory mediator. Additionally, PAF regulates the contractile functions of various types of smooth muscle (SM), such as the (1) endothelium-dependent relaxation of vascular SM; (2) contraction and epithelium-dependent relaxation of airway SM; (3) contraction of gastrointestinal SM; and (4) contraction of uterine SM, which occurs more strongly in pregnant females.
View Article and Find Full Text PDFPLoS Pathog
November 2024
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, United States of America.
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus and the leading cause of infectious disease related birth defects worldwide. How the immune response modulates the risk of intrauterine transmission of HCMV after maternal infection remains poorly understood. Maternal T cells likely play a critical role in preventing infection at the maternal-fetal interface and limiting spread across the placenta, but concerns exist that immune responses to infection may also cause placental dysfunction and adverse pregnancy outcomes.
View Article and Find Full Text PDFEpilepsia Open
December 2024
Neurology Department, Ignace Deen Teaching Hospital, Conakry, Guinea.
Epilepsy is a significant public health problem. More than 50 million people worldwide live with epilepsy, and over three-quarters of them are in low- and middle-income countries. The situation in Chad regarding people with epilepsy is challenging to assess, starting from the shortage of scientific data, the inadequacy of technical facilities, the lack of human resources, and the inadequacy of government action.
View Article and Find Full Text PDFJ Clin Microbiol
December 2024
Department of Medical Laboratory Science, Marquette University, Milwaukee, Wisconsin, USA.
Infect Immun
December 2024
Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
CD1 is an antigen-presenting glycoprotein homologous to MHC I; however, CD1 proteins present lipid rather than peptide antigens. CD1 proteins are well established to present lipid antigens of (Mtb) to T cells, but understanding the role of CD1-restricted immunity in response to Mtb infection has been limited by the availability of animal models naturally expressing the CD1 proteins implicated in human response: CD1a, CD1b, and CD1c. Guinea pigs, in contrast to other rodent models, express four CD1b orthologs, and here we utilize the guinea pig to establish the kinetics of gene and protein expression of CD1b orthologs, as well as the Mtb lipid-antigen and CD1b-restricted immune response at the tissue level over the course of Mtb infection.
View Article and Find Full Text PDFVirology
October 2023
Department of Microbiology and Immunology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-0436, USA; Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-0436, USA; Sealy Institute for Vaccine Sciences, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-0436, USA. Electronic address:
CD4 and CD8 tissue resident memory cells (TRM) express many shared anti-viral activities upon re-exposure to virus. CD4 T cells were depleted from HSV-immune guinea pigs to identify CD4-dependent functions in the vaginal mucosa following HSV-2 challenge. The incidence of animals shedding HSV-2 fell rapidly after challenge in control animals but remained significantly higher through day four post infection in CD4-depleted animals.
View Article and Find Full Text PDFAIDS Care
January 2025
Division of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Papua New Guinea lacks data characterising the sexual health needs of younger key populations (KP): female sex workers (FSW) and commercially and sexually exploited girls (CSE), men who have sex with men (MSM), and transgender women (TGW). Biobehavioural surveys among KP were conducted in three cities. We conducted unweighted and weighted analysis for sample and population proportions, respectively.
View Article and Find Full Text PDFHear Res
December 2024
Oregon Hearing Research Center, Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, OR 97239, USA; Department of Biomedical and Clinical Sciences, Linköping University, SE-581 83 Linköping, Sweden. Electronic address:
Low-frequency hearing is critically important for speech and music perception. However, technical and anatomical limitations previously made it difficult to study the mechanics of the low-frequency parts of the cochlea, but this changed with the introduction of optical coherence tomography vibrometry. With this technique, sound-evoked vibration can be measured from the apex of a fully intact cochlea.
View Article and Find Full Text PDFBMJ Glob Health
October 2024
Infection Control Unit, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
PLoS One
November 2024
Centre for Ecology and Conservation, Faculty of Environment, Science and Economy, University of Exeter, Penryn, Cornwall, United Kingdom.
Understanding species distribution across habitats and environmental variables is important to inform area-based management. However, observational data are often lacking, particularly from developing countries, hindering effective conservation design. One such data-poor area is the Gulf of Guinea, an understudied and biodiverse region where coastal waters play a critical role in coastal livelihoods.
View Article and Find Full Text PDFPLoS One
November 2024
Department of Nursing, International University of Business Agriculture and Technology, Dhaka, Bangladesh.
Introduction: Malaria poses a serious issue for pregnant women in African regions. It is crucial to comprehend the various factors that impact receiving IPTp during ANC checkups. These are important for the well-being of both pregnant mothers and their unborn children.
View Article and Find Full Text PDFbioRxiv
October 2024
UMR7206 Eco-anthropologie, CNRS, MNHN, Université Paris Cité, France.
Human admixture history is rarely a simple process in which distinct populations, previously isolated for a long time, come into contact once to form an admixed population. In this study, we aim to reconstruct the complex admixture histories of the population of São Tomé, an island in the Gulf of Guinea that was the site of the first slave-based plantation economy, and experienced successive waves of forced and deliberate migration from Africa. We examined 2.
View Article and Find Full Text PDFSci Rep
November 2024
School of Applied Sciences, Papua New Guinea University of Technology, Lae, 411, Morobe Province, Papua New Guinea, Papua New Guinea.
The study of research proposes a systematic pattern for optimization and fabrication of a sustainable-cost effective electrochemical sensor made by Bi-CdFeO (BCDF) nanoparticle and graphite powder. The structural examinations of synthesized BCDF materials were analyzed by specific spectral techniques viz.; P-XRD, SEM-EDX, TEM, XPS, FT-IR and DRS techniques.
View Article and Find Full Text PDFJ Travel Med
November 2024
Service de maladies infectieuses et tropicales, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Math Biosci
December 2024
School of Computer Science and Applied Mathematics, University of the Witwatersrand, Johannesburg, South Africa. Electronic address:
We construct a new metapopulation model for the transmission dynamics and control of the Ebola Virus Disease (EVD) in an environment characterized by considerable migrations and travels of people. It is an extended SEIR model modified by the addition of Quarantine and Isolated compartments to account for travelers who undergo the exit screening. The model is well-fitted by using the reported cases from the neighboring countries Guinea, Liberia and Sierra Leone where the 2014-2016 Ebola outbreak simultaneously arose.
View Article and Find Full Text PDFCommun Biol
October 2024
Centre for Tuberculosis Research, Tuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad-Gurugram expressway, Faridabad, Haryana, India.
The expansion of VapBC TA systems in M. tuberculosis has been linked with its fitness and survival upon exposure to stress conditions. Here, we have functionally characterized VapBC13 and VapBC26 TA modules of M.
View Article and Find Full Text PDFBMJ Paediatr Open
October 2024
Center for Epidemiology and Research in Population Health (CERPOP), UMR 1295, Inserm, University Paul Sabatier Toulouse 3, Toulouse, France.
BMJ Open
October 2024
Department of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia.
Objective: To assess the socioeconomic inequality in postnatal care (PNC) utilisation and its contributors among women in 14 sub-Saharan African countries with high maternal mortality.
Design: Community-based cross-sectional study using Demographic Health Survey SETTING: Africa countries with the highest maternal mortality ratio (14 countries) PARTICIPANTS: All women who had given birth within 2 years prior to the survey (n=64 912) PRIMARY OUTCOMES: Postnatal care utilisation RESULTS: The percentage of women who had PNC utilisation was lowest in Ethiopia (23.4%: 95% CI: 22.
Cell
November 2024
Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA. Electronic address:
J Am Vet Med Assoc
February 2025
Objective: To describe the complications, surgical outcome, and prognosis associated with cystotomies in guinea pigs.
Methods: A retrospective review of medical records of guinea pigs undergoing cystotomy for uroliths or urethroliths between 2010 and 2023.
Results: 25 guinea pigs were included in the study.
Vet Radiol Ultrasound
January 2025
Department of Veterinary Medicine, Universidade de São Paulo, Campus de Pirassununga FZEA, Pirassununga, São Paulo, Brazil.
This case report refers to a 1-year-old Guinea pig showing signs of anorexia and antipain posture. On abdominal radiography, five rounded mineral opaque structures were evident in the mid-caudal abdomen. On ultrasound, a right seminal vesicle with a reduction in diameter was observed, containing less echogenic material than the contralateral one, with five oval structures with a hyperechogenic contour and a central hypoechogenic area, forming acoustic shadowing.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
November 2024
Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire (IBMC), Architecture et Réactivité de l'ARN, Strasbourg 67000, France.
spp. are the causative agents of shigellosis, which remains a leading cause of death in children under the age of 5. Symptoms of shigellosis include bloody diarrhea, associated to colon hemorrhage; in more severe cases bacteremia is induced.
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