508 results match your criteria: "Guarulhos University[Affiliation]"

Background: We aimed to evaluate changes in buccal bone thickness (BBT), buccolingual dental inclinations (BLI), and transversal widths (TW) after treatment using a passive self-ligating system.

Material And Methods: Pre- and posttreatment cone-beam computed tomography images (CBCT) of 21 Class I patients (initial mean age: 14.99 ± 1.

View Article and Find Full Text PDF

Objective: This university-based retrospective study aimed to assess the performance of the implant disease risk assessment (IDRA) in predicting peri-implantitis.

Material And Methods: Patients with implants loaded for at least 1 year were included. Peri-implantitis development was the outcome, while the IDRA score and its eight vectors were the predictors.

View Article and Find Full Text PDF

All cultivated Patescibacteria, or CPR, exist as obligate episymbionts on other microbes. Despite being ubiquitous in mammals and environmentally, molecular mechanisms of host identification and binding amongst ultrasmall bacterial episymbionts are largely unknown. Type 4 pili (T4P) are well conserved in this group and predicted to facilitate symbiotic interactions.

View Article and Find Full Text PDF

What challenges hinder the adoption of antimicrobial surface in the dental implant market?

Expert Rev Med Devices

December 2024

Department of Prosthodontics and Periodontology, Piracicaba Dental School, Universidade Estadual de Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.

Introduction: Implant failures resulting from peri-implant infections can have substantial consequences, underscoring the urgent need for effective strategies to prevent biofilm formation on implant surfaces. However, despite advancements in antimicrobial surface technologies, significant challenges persist in translating these innovations into clinically viable solutions.

Areas Covered: This article provides an overview of the limitations of current treatment protocols and explores the potential of antimicrobial surface treatments for controlling such infections.

View Article and Find Full Text PDF
Article Synopsis
  • Ozone therapy may enhance healing for diabetic foot ulcers (DFUs) by boosting antioxidant enzyme activity, regulating growth factors, and improving blood flow while also providing antibacterial effects.
  • * A systematic review revealed six studies that met eligibility criteria, showing ozone therapy led to higher healing rates, shorter hospital stays, and better blood glucose levels among patients.
  • * Despite promising findings, the studies had significant risk of bias, highlighting the need for more rigorous research to confirm ozone therapy's effectiveness in treating DFUs.
View Article and Find Full Text PDF

The Impact of Nutritional Components on Periodontal Health: A Literature Review.

Nutrients

November 2024

Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus (RHCC), Haifa P.O. Box 9602, Israel.

Periodontitis is a chronic inflammatory disease driven by the accumulation of bacterial plaque and the host's immune response, leading to the destruction of periodontal tissues. Nutrition, particularly the intake of micronutrients with anti-inflammatory and antioxidant properties, plays a crucial role in maintaining periodontal health. This review explores the impact of various micronutrients-vitamins (A, B, C, D, E), minerals (calcium, iron, zinc, potassium, copper, manganese, selenium), and omega-3 fatty acids-on periodontal disease prevention and management.

View Article and Find Full Text PDF

The necessity for regenerating peri-implant and periodontal tissues is increasingly apparent. Periodontal diseases can result in a significant loss of clinical attachment level, and tissue regeneration stands as the ultimate goal of periodontal therapy. With the rise of osseointegration, the prosthetic rehabilitation of missing teeth using dental implants has surged, leading to a frequent need for alveolar bone regeneration around implants.

View Article and Find Full Text PDF
Article Synopsis
  • - Craniofacial and alveolar bone defects from various causes (like tumors, trauma, or tooth loss) present significant challenges in tissue engineering and dental surgery, especially in cases of periodontal disease.
  • - Specialized pro-resolving lipid mediators (SPMs) like lipoxins, resolvins, protectins, and maresins are being researched for their potential to enhance bone regeneration and restore tissue healing in craniofacial applications.
  • - A total of 19 pre-clinical studies examined the effects of SPMs on bone regeneration, showing that SPMs notably increased new bone formation by about 14.85% and reduced defect size, with RvE1 and RvD2 demonstrating
View Article and Find Full Text PDF

The present review summarizes the findings from human histological studies conducted over the past 20 years at the University of Guarulhos, Brazil, examining the impact of various implant surface topographies and smoking on peri-implant bone response. Seven different implant surfaces were evaluated in 90 partially or completely edentulous individuals using a total of 123 micro-implants. Histometric parameters, including bone-implant contact (BIC%), bone area within the threads (BA%), and bone density (BD), were assessed after an 8-week healing period.

View Article and Find Full Text PDF

Navigating the Landscape of Periodontitis Nonsurgical Treatment: A Metatrend Study of The Scientific Production and Trends From 2001-2020.

Braz Dent J

October 2024

Department of Periodontology, Dental Research Division, Guarulhos University, Praça Tereza Cristina, 88 - Centro, Guarulhos, São Paulo 07023-070, Brazil.

Nonsurgical therapies have been recommended and employed as a less invasive and cost-effective modality in managing periodontitis. In this context, different therapeutic protocols have been tested in the last decades. Therefore, mapping the scientific trends and patterns provides critical insights into the state of research in the field, which has not been explored for overall nonsurgical periodontitis treatment studies.

View Article and Find Full Text PDF

Increased Resolvin E1 Production by Peripheral Blood Mononuclear Cells in Periodontitis Patients: Pilot Study.

Braz Dent J

October 2024

Pontificia Universidad Javeriana, Centro de investigaciones odontológicas, Facultad de Odontología, Bogotá, Colombia.

This study quantified the production of the pro-resolving agent Resolvin E1 by peripheral blood mononuclear cells (PBMC) from 20 systemically healthy volunteers with and without periodontitis after stimulation with lipopolysaccharide (LPS) from Porphyromonas gingivalis (Pg). Ten periodontitis patients and 10 healthy volunteers (30-50 years old), matched by age and sex, were recruited. Peripheral blood mononuclear cells were isolated and stimulated in culture plates for 24 hours with Pg LPS.

View Article and Find Full Text PDF

Immediate Loading Full-Arch 3D-Printed Implant-Supported Fixed Rehabilitation: A Case Report with 24-Month Follow-Up.

Medicina (Kaunas)

October 2024

Department of Periodontology and Oral Implantology, Dental Research Division, Guarulhos University, 1 Tereza Cristina Sq., Guarulhos 07023-070, SP, Brazil.

Implant-supported immediate loading full-arch rehabilitation has been documented in the literature. More recently, computed surgical guides have frequently been used since they facilitate planning and performing surgical treatment without the need to raise a flap, thus reducing trauma and morbidity. This case report describes an immediate full-arch, fixed rehabilitation with full loading placed on four commercially available 3D-printed implants, with a 24-month follow-up.

View Article and Find Full Text PDF

Implantable biomedical devices have found widespread use in restoring lost functions or structures within the human body, but they face a significant challenge from microbial-related infections, which often lead to implant failure. In this context, antimicrobial hydrogels emerge as a promising strategy for treating implant-associated infections owing to their tunable physicochemical properties. However, the literature lacks a comprehensive analysis of antimicrobial hydrogels, encompassing their development, mechanisms, and effect on implant-associated infections, mainly in light of existing in vitro, in vivo, and clinical evidence.

View Article and Find Full Text PDF

To provide an overview of the use of autogenous platelet concentrates (APCs) in periodontal regeneration and to conduct a systematic review (SR) of the treatment outcomes of periodontal intrabony defects by using platelet-rich fibrin (PRF) compared with other commonly utilized modalities. The eligibility criteria comprised randomized controlled trials (RCTs) comparing the clinical outcomes of PRF with that of other modalities. Studies were classified into 21 categories and into five different groups as follows: Group I (1) open flap debridement (OFD) alone versus OFD/PRF, (2) OFD versus Titanium-PRF (T-PRF) Group II, (3) Comparative PRF protocols (PRF vs.

View Article and Find Full Text PDF

Background: With advancements in orthodontic technology, treatment durations have shortened, often concluding at earlier ages. This shift prompts scrutiny of contemporary retention and post-treatment protocols. The study aimed to assess current professional preferences, compare them against patient age and treatment duration, and investigate the potential impacts of reduced treatment times on professional protocols, particularly when treatment concludes before pubertal growth.

View Article and Find Full Text PDF

The objective of the study was to compare the treatment outcomes of periodontal furcation defects by using platelet-rich fibrin (PRF) with other commonly utilized modalities. The eligibility criteria comprised randomized controlled trials (RCTs) comparing the clinical outcomes of PRF with those of other modalities for the treatment of furcation defects. Studies were classified into 11 categories in 3 different groups as follows: Group I (addition of PRF): (1) open flap debridement (OFD) alone versus OFD/PRF, (2) OFD/bone graft (OFD/BG) versus OFD/BG/PRF; Group II (comparative studies to PRF): (3) OFD/BG versus OFD/PRF, (4) OFD/collagen membrane versus OFD/PRF, (5) OFD/PRP versus OFD/PRF, (6) OFD/rhBMP2 versus OFD/PRF; and Group III (addition of biomaterial/biomolecule to PRF): OFD/PRF versus … (7) OFD/PRF/BG, (8) OFD/PRF/amniotic membrane (AM), (9) OFD/PRF/metformin, (10) OFD/PRF/bisphosphonates, (11) OFD/PRF/statins.

View Article and Find Full Text PDF

This study evaluated the efficacy of synthetic bone blocks, composed of hydroxyapatite (HA) or β-tricalcium phosphate (B-TCP), which were produced by additive manufacturing and used for the repair of critical size bone defects (CSDs) in rat calvaria. Sixty rats were divided into five groups ( = 12): blood clot (CONTROL), 3D-printed HA (HA), 3D-printed β-TCP (B-TCP), 3D-printed HA + autologous micrograft (HA+RIG), and 3D-printed β-TCP + autologous micrograft (B-TCP+RIG). CSDs were surgically created in the parietal bone and treated with the respective biomaterials.

View Article and Find Full Text PDF

Micro-arc driven porous ZrO coating for tailoring surface properties of titanium for dental implants application.

Colloids Surf B Biointerfaces

January 2025

Department of Prosthodontics and Periodontology, Piracicaba Dental School, Universidade Estadual de Campinas (UNICAMP), Av Limeira, 901, Piracicaba, São Paulo 13414-903, Brazil. Electronic address:

Titanium (Ti) is an ideal material for dental implants due to its excellent properties. However, corrosion and mechanical wear lead to Ti ions and particles release, triggering inflammatory responses and bone resorption. To overcome these challenges, surface modification techniques are used, including micro-arc oxidation (MAO).

View Article and Find Full Text PDF

Baccharis mattogrosensis is a species from Asteraceae which has been used in Brazilian folk medicine to treatment of several illnesses, including those caused by parasites. In the present work, the MeOH extract of aerial parts of B. mattogrosensis was subjected to chromatographic fractionation to afford three flavonoids: apigenin (1), quercetin (2), and kaempferol (3) as well as a mixture three chlorogenic acids: 3,4-O-dicaffeoylquinic (4), 3,5-O-dicaffeoylquinic (5), and 4,5-O-dicaffeoylquinic (6) acids.

View Article and Find Full Text PDF

This clinical report presents a technique to reconstruct extensively resected mandibles using a combination of autologous bone grafts and additive manufacturing techniques. Mandibular defects, often arising from trauma, tumors, or congenital anomalies, can severely impact both function and aesthetics. Conventional reconstruction methods have their limitations, often resulting in suboptimal outcomes.

View Article and Find Full Text PDF
Article Synopsis
  • - The human mouth and nose can harbor opportunistic pathogens like Klebsiella, which often lead to serious infections and exhibit antibiotic resistance; understanding how these microbes spread among healthy and sick individuals is crucial.
  • - Research showed that Klebsiella species can thrive in stressed environments (like hospitals) by outcompeting other bacteria when nutrients are scarce, indicating their potential to become dominant in these settings.
  • - Analysis revealed that antibiotic-resistant Klebsiella strains found in healthy individuals are genetically similar to those isolated from patients, suggesting a possible link between community-acquired and hospital infections.
View Article and Find Full Text PDF

The study aimed to evaluate the antithrombotic action of pulp oil (AAPO) in natura, in an in vitro experimental model. AAPO was obtained by solvent extraction, and its chemical characterization was performed by gas chromatography coupled to a mass spectrometer (GC-MS). In vitro toxicity was evaluated with the Trypan Blue exclusion test and in vivo by the model.

View Article and Find Full Text PDF

Mangaba is a fruit native to Brazil, rich in bioactive compounds. To evaluate physicochemical composition, bioactive compounds, antioxidant and antifungal activity of mangaba fruit pulp. Moisture, ash, protein, lipid, energy values and phenolic compounds were determined.

View Article and Find Full Text PDF
Article Synopsis
  • * Treatment with CNV at the highest concentration (1600 μg/mL) significantly reduced more bacterial species compared to amoxicillin (25 vs. 13 species) and showed a superior effect in decreasing the metabolic activity of the biofilm.
  • * The findings suggest that CNV could be a promising alternative for managing dental biofilms and reducing their harmful effects, outperforming traditional antibiotic treatment.
View Article and Find Full Text PDF

Background: The aim of this study was to evaluate the incidence of preloading crestal bone loss (PLCBL) and to identify the patient-related and implant-related factors associated with PLCBL.

Methods: This retrospective cohort examined the dental records of patients who received at least one dental implant. PLCBL was defined as a reduction ⩾0.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: