Immediate effects of a buffered knee orthosis on gait in stroke patients with knee hyperextension.

Background: Patients exhibit considerable variations in gait patterns especially in knee hyperextension in the stance phase after stroke. If knee hyperextension is untreated it may lead to pain, reduced independence in activities of daily living, deformities and instability.

Objective: The aim of this study was to investigate the immediate effects of a buffered knee orthosis on gait of stroke patients with knee hyperextension.

Advances in cell death - related signaling pathways in acute-on-chronic liver failure.

Acute-on-chronic liver failure (ACLF) has been a hot spot in the field of liver disease research in recent years, with high morbidity, rapid course change and high mortality. Currently, there is the absence of specific treatment in clinical practice. Liver transplantation has the best therapeutic effect, but it is prone to have internal environment disorder and liver cell death after transplantation, which leads to the failure of transplantation.

The effectiveness and safety of Sun tip-flexible ureterorenoscope for the management of kidney stones: A protocol for systematic review and meta-analysis of randomized controlled trials.

Introduction: Kidney stone is one of the urinary system diseases with a high incidence. In this study, we will evaluate the effectiveness and safety of Sun tip-flexible ureterorenoscope treating patients with kidney stone.

Methods And Analysis: English and Chinese literature about Sun tip-flexible ureterorenoscope treatment for kidney stones published before October 31, 2020 will be systematic searched in PubMed, Embase, Web of Science, Cochrane Library, Open Grey, Clinicaltrials.

Effective Treatment of NSCLC with Surgery After Nivolumab Combined with Chemotherapy: A Case Report and Brief Review of the Literature.

Introduction: Immuno checkpoint inhibitors (ICIs) including anti-PD-L1 antibody have shown certain therapeutic effects on various cancer types. Here, we reported a case of the patient with resectable non-small cell lung cancer (NSCLC) showing a complete response to nivolumab combined with chemotherapy.

Patient Information: A 66-year-old male was diagnosed with stage IIIA large cell lung cancer, cT2N2M0, who was considered impossible to have a tumor resection due to his right hilar node enlargement.

Meta analysis of the curative effect of acupuncture on post-stroke depression.

Objective: To systematically evaluate the curative effect of acupuncture on post-stroke depression (PSD).

Methods: The internet was used to retrieve the Wanfang Medical Data System, Chinese Periodical Net, the Weipu Information Resources System, PubMed and the Cochrane Library Database. Relevant articles, up to September 2010, were manually retrieved.

[Effect of acupuncture on the activity of the peripheral blood T lymphocyte subsets and NK cells in patients with colorectal cancer liver metastasis].

Objective: To study the effect of acupuncture on the immune function of patients with colorectal cancer liver metastasis.

Methods: Sixty cases with colorectal cancer liver metastasis confirmed by pathology and mageology diagnosis were treated with acupuncture. Zusanli (ST 36), Sanyinjiao (SP 6), Neiguan (PC 6), Shangjuxu (ST 37), Hegu (LI 4), Taixi (KI 3), Taichong (LR 3) ,Yinlingquan (SP 9), Yanglingquan (GB 34), etc.

Effects of the intelligent-turtle massage on the physical symptoms and immune functions in patients with chronic fatigue syndrome.

Objective: To evaluate the effects of the intelligent-turtle massage on the physical symptoms and immune functions in patients with chronic fatigue syndrome (CFS).

Methods: 182 cases of CFS were randomly divided into an experimental group of 91 cases treated by the intelligent-turtle massage, and a control group of 91 cases treated with the conventional massage method. After 2 courses of treatment, the therapeutic effects were statistically analyzed with the accumulated score for the improved clinical symptoms; and the changes of IgA, IgM and IgG were compared in 96 cases.

[Integrative medical strategy for treatment of senile lung cancer].

Senile lung cancer has its own characteristics, thus its treatment is also particular. Viewing from the therapeutic angle of integrative medicine, the current status of research and application of various clinical treatment strategies and measures for senile lung cancer were preliminarily reviewed in this paper in items of surgical operation, chemotherapy, radiotherapy, molecular target drugs therapy and Chinese medical therapy.

[Analysis of prescription for special disease/syndrome--compatibility of absorbed/metabolized components from original formula--a thinking of research].

What is the pharmacodynamic active components in Chinese medical prescription is a key problem in urgent need to solve for the development of traditional Chinese medicine (TCM). A new thinking of TCM research, "analysis of prescription for special disease/syndrome--compatibility of absorbed/metabolized components from original prescription", was proposed firstly, to analyze and seek out the components or metabolites originated from the administered prescription in blood serum of the organisms with special disease and syndrome. Secondly, to study the compatibility of these absorbed/metabolized components.

Thirty-six cases of urinary retention treated by acupuncture.

Objective: To observe the clinical therapeutic effects of acupuncture on urinary retention.

Methods: 36 cases of urinary retention were treated by acupuncture at the following points: 1) Qugu (CV 2), Zhongji (CV 3) Guanyuan (CV 4), Sanyinjiao (SP 6) and Yinlingquan (SP 9); 2) Shenshu (BL 23), Pangguangshu (BL 28), Ciliao (BL 32) and Weiyang (BL 39).

Results: 30 cases were cured, 4 cases improved and 2 cases failed, with a curative rate of 83.

[Professor ZHANG An-li's experiences on treatment of intractable facial paralysis].

Prof. Zhang An-li's clinical experiences on treatment of intractable facial paralysis are introduced. According to own many year's clinical experiences and in combination with modified heat-producing needling and fire needle therapy, Prof.

[Study on synergic or antagonistic effects of different acupoint groups on vertebro-basilar insufficiency].

Objective: To observe the synergic or antagonistic effect of needling acupoints Fengchi (GB 20) and Tianzhu (BL 10), and Jiaji C4-C6 (EX-B2) on vertebro-basilar insufficiency (VBI).

Methods: Self-control method was used and 20 cases of VBI were respectively treated with acupuncture at Fengchi (GB 20) and Tianzhu (BL 10), Jiaji (EX-B2). Their combination and the changes of vertebro-basilar artery's (VBA) systolic velocity of blood flow was detected.

[Clinical observation on children with language disorder of cerebral palsy treated by acupuncture].

Objective: To observe therapeutic effect of acupuncture on language disorder of cerebral palsy.

Methods: Ninety-eight cases of language disorder of cerebral palsy were randomly divided into an acupuncture group (n = 76) and a control group (n = 22). The acupuncture group were treated by needling main acupoints Sishenzhen, Niesanzhen, Naosanzhen, Zhisanzhen, Shesanzhen, Fengchi (GB 20) and Yamen (GV 15), and the control group by oral administration of pyrithioxine 0.

[Comparative study on therapeutic effects of Baihui (GV 20), Shuigou (GV 26) and Shenmen (HT 7) in treatment of vascular dementia].

Objective: To compare the relative characteristics of Baihui (GV 20), Shuigou (GV 26) and Shenmen (HT 7) in treatment of vascular dementia.

Methods: Fifty cases of vascular dementia (VD) were divided into 5 groups randomly. The patients in the group A were treated by acupuncture at routine acupoints.

[Studies on functional genes of Chinese herbal medicine].

In order to establish the foundation for modernization of Chinese herbal medicine, discovery of the functional genes related with the bioactive components of Chinese herbs and the rules of their expression was progressed for determining the regulatory mechanism, obtaining the core metabolic pathway and key regulatory factors of the medicinal components synthesis. In this article, the studies about plant's functional genes at home and abroad was introduced in three aspects: the pattern plants (rice, thaliana, etc.), the main technologic strategy (gene expression differentia, sequential tag of gene expression, DNA microarray technique and gene expression sequential analysis) and bio-informative method (comparative genomics).

[Effect of borneol on the intercellular tight junction and pinocytosis vesicles in vitro blood-brain barrier model].

Objective: To explore the mechanism of borneol in opening the blood-brain barrier (BBB).

Methods: Borneol contained serum was prepared and using Matin-Darby canine kidney epithelium (MDCKE) cell line as the in vitro BBB model to observe the effects of borneol on intercellular tight junction (ICTJ) and pinocytosis vesicles of BBB model.

Results: Borneol reduced the ICTJ and caused increase of the number and enlarged the diameter of vesicles.

[Effect of niupo zhibao pellet on transforming growth factor-beta1 and its receptor's expression in endotoxic shock rats with lung injury].

Objective: To observe the influence of Niupo Zhibao pellet (NZP) on transforming growth factor-beta1 (TGF-beta1) and its receptor's expression.

Methods: Endotoxic shock model was established by intravenous injection of lipopolysaccharide (LPS) 1.5 mg/kg and intraperitoneal injection of D-galactosamine 100 mg/kg, and intervened by NZP, TGF-beta1 and its receptor's expression in lung tissue were detected by immunohistochemical method.

[Study on improvement of islet beta cell function in patients with latent autoimmune diabetes mellitus in adults by integrative Chinese and Western medicine].

Objective: To study the effect of integrative Chinese and Western medicine (ICWM) on improvement of the islet beta cell function in treating patients with latent autoimmune diabetes mellitus in adults (LADA).

Methods: Eighty-four patients of LADA were randomly divided into 3 groups (20 in A, 33 in B and 31 in C), they were treated respectively with sulfonylurea, insulin and combination of insulin and Chinese medicine. The changes before and after treatment in blood glucose, glycohemoglobin and islet beta cell function were observed.

[Clinical observation on treatment of acute gouty arthritis by tongfengkang].

Objective: To objectively evaluate the clinical therapeutic effect of tongfengkang (TFK) in treating acute gouty arthritis.

Methods: Adopting randomized single blinded controlled trial, the 40 patients were equally divided into two groups. The tested group was treated with TFK, the control group was treated with indomethacin and allopurinol, the therapeutic course for both groups was 10 days.

[Exploration on the relationship between pathogenesis for yin-deficiency of acute myocardial infarction and immediate prognosis as well as its mechanism].

Objective: To study the relationship between pathogenesis for Yin-deficiency of acute myocardial infarction (AMI) and immediate prognosis as well as its neuro-endocrine mechanism.

Methods: According to the TCM standard of Syndrome Differentiation of Deficiency Syndrome, 194 patients with AMI were classified into the typical Yin-deficiency group (n = 26), the non-typical Yin-deficiency group (n = 61) and the non-Yin-deficiency group (n = 107). Their venous blood samples were collected in the morning while lying on their backs to detect plasma levels of adrenaline, noradrenaline, aldosterone, atrial natriuretic peptide (ANP), corticoid and myocardial enzymes, as well as their hospitalization days and mortality in hospitalized period were calculated and compared in the three groups, with the 30 healthy persons as control.

[Effect of overall alkali of Tongbiling on CD69 expression activated mouse T lymphocytes].

Aim: To investigate the effect of overall alkali of Tongbiling(TBL) on CD69 expression on activated mouse T lymphocytes and its possible mechanism.

Methods: Phorbol 12,13-dibutyrate(PDB) or concanavalin (ConA) were added successively into mouse lymphocytic culture with various concentration of overall alkali TBL. After 24 hours, CD69 expression rate on mouse T lymphocytes activated with PDB or ConA was analyzed by flow cytometry.

[Effect of combination of syndrome differentiation depending treatment and chemotherapy on prognostic factors in treating mid-late patients with non-small call lung cancer].

Objective: To observe the effect of combination of Syndrome Differentiation (SD) depending treatment and chemotherapy on prognostic factors in patients with non-small cell lung cancer (NSCLC).

Methods: One hundred and twenty patients with NSCLC were randomly divided into the TCM group, the western medicine (WM) group and the combined TCM and WM (TCM-WM) group. Besides the conventional supporting and symptomatic treatment given to all the 3 groups, to the TCM group, Chinese drug medication according to patients' SD (intravenons injection, decoction or Xiaoji Decoction) was given, to the WM group chemorherapy was given, and to the TCM-WM group, all the treatment used in both TCM and WM group were given.

[Observation on efficacy of CT positioning scalp circum-needling combined with Chinese herbal medicine in treating poly-infarctional vascular dementia].

Objective: To observe the short-term effect of patients with poly-infarctional vascular dementia (PIVD) treated by CT positioning scalp circum-needling (SCN) combined with Chinese herbal medicine.

Methods: Eighty-nine patients of PIVD were enrolled and divided into the treated group (n = 57) and the control group (n = 32). They were all treated with oral taking of Fuyuan mixture (FYM, consisted of ginseng, medlar, salvia, bitter cardamon, etc).

[Effect of electro-acupuncture on calcium content in neurocytes of focal cerebral ischemia].

Objective: To study the effect of electro-acupuncture (EA) in regulating calcium (Ca2+) content in brain neurocytes of rats with focal cerebral ischemia.

Methods: The changes of Ca2+ content in ischemic neurocytes were observed by using laser confocal scanning microscope.

Results: Ca2+ content did not change significantly in cerebral cortex when the brain ischemia occurred for 1 hr, but it raised significantly in striatum neurocytes.

[Effect of tongbiling on synoviocyte function in adjuvant arthritis rats].

Objective: To study the effect of Tongbiling (TBL) on the proliferation of synovial fibroblast and interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-alpha) and postaglandin E2(PGE2) secretion by synoviocytes in adjuvant arthritis (AA) rats.

Methods: Synovial fibroblasts was derived from culture of tissue piece. The effect of primary synoviocyte culture supernatants on the fibroblast proliferation were assayed and IL-1, TNF-alpha bioactivity and PGE2 content of supernatants of cultured synoviocytes were measured.