[Urinary S-phenylmercapturic acid variation in benzene exposed].

Objective: To observe the urinary S-phenylmercapturic acid (S-PMA) variation in the benzene dynamic exposed rat models and benzene exposed workers, and study the feasibility of use of urinary S-PMA as the biomarker in benzene exposed.

Methods: In an animal model study, forty-eight adult Wistar rats were randomly divided into 4 groups: the control group, low-dose group, middle-dose group and high-dose group. The exposed groups were dynamically exposed for 28 days (4 periods) by benzene and the concentration was monitored.

[A study on lymphocyte DNA damage in traffic policemen in Guangzhou].

Objective: To study the effect of occupational exposure to traffic exhaust and smoking on DNA damage in traffic policemen.

Methods: 812 traffic policemen (741 men and 71 women, 130 of office-work and 682 of outside work) from 8 districts in Guangzhou were investigated. Blood samples were taken by venipuncture and lymphocytes were collected by using lymphocyte separation medium and centrifugation.

[A prospective cohort study on the effect of occupational dust exposure and smoking on mortality].

Objective: To study the effect of dust exposure and smoking on mortality.

Methods: Based on the Guangzhou Occupational Health Surveillance Record System established in 1989-1992, 61,648 factory workers, aged > or = 30, occupationally exposed to dust and non-exposure to dust or any other hazardous substances(controls), were included in a prospective cohort study.

Results: (1) 28 were lost to follow-up.