6 results match your criteria: "Guangzhou Command Wuhan General Hospital[Affiliation]"
Effect of prazosin on diabetic nephropathy patients with positive α1-adrenergic receptor autoantibodies and refractory hypertension.
Exp Ther Med
January 2015
Graduate College, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
To investigate the effect of prazosin on patients with diabetic nephropathy (DN), α1-adrenergic receptor (α1-R) autoantibodies and refractory hypertension, a total of 126 patients with DN and hypertension were recruited. The patients were divided into a refractory hypertension group, (n=76) and a non-refractory hypertension group (n=50). The epitope of the second extracellular loop of the α1-R (192-218) was synthesized and an enzyme-linked immunosorbent assay (ELISA) was performed to detect serum autoantibodies.
View Article and Find Full Text PDFAutoantibodies against β1 receptor and AT1 receptor in type 2 diabetes patients with left ventricular dilatation.
Cardiology
July 2015
Department of Endocrinology, Guangzhou Command Wuhan General Hospital, Wuhan, PR China.
Objectives: To explore the relationship between the autoantibodies against the β1 and AT1 receptors and left ventricular dilatation in patients with type 2 diabetes (T2DM).
Methods: The autoantibodies against the β1 and angiotensin II type 1 (AT1) receptors of T2DM patients with and without hypertension were screened by ELISA. Multiple logistic regression was used to analyze the risk factors for left ventricular dilatation.
[Angiotensin converting enzyme gene and exercise-induced silent myocardial ischemia in type 2 diabetes mellitus].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
April 2005
Department of Endocrinology, Guangzhou Command Wuhan General Hospital of PLA, Wuhan. Hubeiì 430070 P. R. China.
Objective: To investigate the relationship between angiotensin converting enzyme (ACE) gene and exercise-induced silent myocardial ischemia (SI) in patients with type 2 diabetes mellitus.
Methods: One hundred and eight patients suffering from type 2 diabetes mellitus with normal rest electrocardiograph and 50 healthy individuals were selected randomly. SI was diagnosed with treadmill exercise test and ACE genotypes were detected with PCR.
Changes in endothelium-dependent arterial dilation before and after subtotal thyroidectomy in subjects with hyperthyroidism.
Clin Endocrinol (Oxf)
September 2004
Department of Endocrinology, Guangzhou Command Wuhan General Hospital of PLA, Wuhan, Hubei Province, PR China.
Article Synopsis
- * Findings indicated that arterial dilation decreased significantly from hyperthyroid to euthyroid stages and further into a transient hypothyroid state after surgery.
- * The results suggest that untreated hyperthyroid patients have more responsive endothelial function compared to when they become euthyroid, highlighting the impact of thyroid status on vascular health.
Apolipoprotein e4 allele is predictor of coronary artery disease death in elderly patients with type 2 diabetes mellitus.
Atherosclerosis
July 2004
The Department of Endocrinology, Guangzhou Command Wuhan General Hospital of PLA, Wuhan 430070, PR China.
The presence of the apolipoprotein (Apo) e4 allele is reported to be associated with the increased risk of coronary artery disease (CAD), as well as the impairment of endothelium-dependent dilation in type 2 diabetes mellitus. Therefore, we hypothesized that the Apo e4 allele increases the death risk from coronary artery disease in type 2 diabetes. From January 1993 to December 1999, 36 type 2 diabetic patients with e4/4 or e4/3, 62 with e3/3 and 33 with e2/2 or e3/2 genotypes were recruited.
View Article and Find Full Text PDFRegular aerobic exercise training improves endothelium-dependent arterial dilation in patients with impaired fasting glucose.
Diabetes Care
March 2004
Department of Endocrinology, Guangzhou Command Wuhan General Hospital of the People's Liberation Army, Wuluo Road 627, Wuhan 430070, Hubei Province, China.