Emission Tuning of Nonconventional Luminescent Materials via Cluster Engineering.

Nonconventional Luminescent Materials (NLMs) with distinctive optical properties are garnering significant attention. A key challenge in their practical application lies in precisely controlling their emission behavior, particularly achieving excitation wavelength-independent emission, which is paramount for accurate chemical sensing. In this study, NLMs (Y1, Y2, Y3, and Y4) are synthesized via a click reaction, and it is found that excitation wavelength-dependent emission correlates with molecular cluster formation.

Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma.

Background: Histone H2B is highly expressed in many types of cancers and is involved in cancer development. H2B clustered histone 9 (H2BC9), a member of the H2B family, plays critical roles in gene expression regulation, chromosome structure, DNA repair stability, and cell cycle regulation. However, the diagnostic and prognostic value of H2BC9 in head and neck squamous cell carcinoma (HNSCC) remains unclear.

The Effect of Resveratrol on Lead-Induced Oxidative Damage and Apoptosis in HT-22 Cells.

Objective: The purpose of this work was to investigate whether resveratrol affects lead-induced oxidative damage in HT-22 cells, characterizing mechanisms and strategies for preventing and treating lead-induced neurotoxicity.

Methods: Various lead and resveratrol concentrations were applied to HT-22 cells over different time periods. First, we established the lead treatment (12.

Recombinant Abelson Tyrosine Protein Kinase (rAbl) Regulates Various Functions of Buffalo Peripheral Blood Mononuclear Cells.

can modulate host immune mechanisms through excretory-secretory products (ESP). As one of the components of ESP, it is unknown whether Abelson tyrosine protein kinase (Abl) is involved in parasite-host immune interaction. To investigate the immunoregulatory function of Abl in , we cloned and expressed the gigantica Abl protein and assessed its effect on specific immune functions of buffalo peripheral blood mononuclear cells (PBMCs).

Association Between Urinary Metal Levels and Chronic Kidney Dysfunction in Rural China: A Study on Sex-Specific Differences.

Background: While current epidemiological studies have documented associations between environmental metals and renal dysfunction, the majority have concentrated on plasma metal levels. The relationship between urinary metal exposure and chronic kidney disease (CKD) remains contentious, particularly within specific demographic groups.

Methods: This cross-sectional study included 2919 rural Chinese adults recruited between 2018 and 2019.

[Simultaneous determination of 51 indazole-type synthetic cannabinoids in urine and blood by online solid-phase extraction-liquid chromatography-linear ion trap mass spectrometry].

To evade legal controls, new psychoactive substances (NPS), which have been designed as substitutes for traditional and synthetic drugs, are gradually dominating the drug market. Synthetic cannabinoids (SCs), which account for the majority of NPS, are rapidly being derivatized; consequently, controlling increasing abuse by merely listing individual compounds is difficult. Therefore, China has included the entire SC category of SCs listed as legal controlled substances since July 1, 2021.

Synthesis, antifungal activity, and molecular simulation study of nootkatone-based thiazole-hydrazone compounds as novel succinate dehydrogenase inhibitor.

Background: Plant diseases cause huge losses in agriculture worldwide every year, but the prolonged use of current commercial fungicides has led to the development of resistance in plant pathogenic fungi. Therefore, there is an urgent need to develop new, efficient, and green fungicides.

Results: Twenty-three nootkatone-based thiazole-hydrazone compounds were designed, synthesized, and characterized by Fourier-transform infrared (FTIR), proton (H) nuclear magnetic resonance (NMR), carbon-13 (C) NMR, and high-resolution mass spectrometry (HRMS).

Biotinylation-based lateral flow assays for pathogenic and total bacteria detection.

Background: It is highly desirable to concurrently evaluate both pathogenic and total bacteria in water and food environments. As a point-of-care platform for biochemical tests, lateral flow assay (LFA) has been widely used for pathogenic bacteria due to its portability and fast time of outcome. However, traditional LFA was unable to detect total bacteria due to the lack of a universal antibody that could bind all the bacteria.

Facile and green fabrication of biodegradable aerogel from chitosan derivatives/modified gelatin as absorbent for oil removal.

Frequent oil spills have caused increasingly severe pollution of marine water bodies. As a result, exploring green and efficient aerogels to tackles oil pollution is in high demand. In this work, a unique strategy for preparing all-biomass aerogel was innovatively proposed.

Effects of aluminum on metabolism of reactive oxygen species and reactive nitrogen species in root tips of different Eucalyptus species.

On acidified soil, the growth of Eucalyptus is seriously restricted by aluminum (Al) stress. Therefore, breeding Eucalyptus species with excellent Al tolerance, developing the genetic potential of species, and improving tolerance to Al stress are important for the sustainable development of artificial Eucalyptus forests. By observing the occurrence and distribution of the main reactive oxygen species (ROS) and reactive nitrogen species (RNS) in root tips of Eucalyptus seedlings under Al stress, this study analyzed change in the growth and physiological indexes of Eucalyptus seedlings under Al stress.

Cell viability assessment by using GelRed/SYTO 9-based double staining.

Cell viability assessment plays a crucial role in biological research, pharmaceutical development, and toxicological identification. Here, we used GelRed, a sensitive and safer nucleic acid dye, to selectively label dead cells with red fluorescence (FL) thus distinguishing dead cells from live ones. Further more, the combined use of GelRed and SYTO 9 (another nucleic acid dye) enabled the clear differentiation in FL spectra between the two physiological statuses.

Lattice Strain-Modulated Trifunctional CoMoO Polymorph-Based Electrodes for Asymmetric Supercapacitors and Self-Powered Water Splitting.

Developing efficient, multifunctional electrodes for energy storage and conversion devices is crucial. Herein, lattice strains are reported in the β-phase polymorph of CoMoO within CoMoO@CoO heterostructure via phosphorus doping (P-CoMoO@CoO) and used as a high-performance trifunctional electrode for supercapacitors (SCs), hydrogen evolution reaction (HER), and oxygen evolution reaction (OER) in alkaline electrolytes. A tensile strain of +2.

A ratiometric fluorescent probe with dual near infrared emission for in vivo ratio imaging of cysteine.

Accurately detecting cysteine (Cys) in vivo is crucial for diagnosing Cys-related diseases. A novel ratiometric fluorescent probe featuring dual near-infrared emission is developed in this study for the in vivo ratio imaging of Cys. The probe comprises a hemicyanine organic small-molecule dye (HCy-CYS) with specific Cys recognition capabilities covalently coupled with carbon dots (CDs) synthesized using glutathione (GSH) as the carbon source (GCDs), forming a unique composite nanofluorescent probe (GCDs@CYS).

Flexible Triboelectric Nanogenerator Patch for Accelerated Wound Healing Through the Synergy of Electrostimulation and Photothermal Effect.

Physiological wound healing process can restore the functional and structural integrity of skin, but is often delayed due to external disturbance. The development of methods for promoting the repair process of skin wounds represents a highly desired and challenging goal. Here, a flexible, self-powered, and multifunctional triboelectric nanogenerator (TENG) wound patch (e-patch) is presented for accelerating wound healing through the synergy of electrostimulation and photothermal effect.

Palladium-catalyzed -arylation of (hetero)aryl chlorides with pyrroles and their analogues.

We present a mild and efficient method for the arylation of N-H heteroarenes using a low-loading Pd/keYPhos catalyst (0.8 mol%). This approach employs inexpensive and structurally diverse aryl chlorides as electrophiles in reactions with indoles, pyrroles, and carbazole, enabling the construction of a wide range of -arylated products.

In vitro metabolism of seven arolyl-derived fentanyl-type new psychoactive substances.

Over the past decade, fentanyl-type new psychoactive substances (F-NPS) have emerged as the most representative synthetic opioids in third-generation drugs. These substances are characterized by their "low" fatal dose and parent drug levels in biological matrices, "fast" rates of derivatization and metabolism, and "many" derivatization sites and analogs. The low levels of parent fentanyl NPS in biological matrices complicate their detection, necessitating the use of characteristic metabolites as biomarkers for forensic analysis.

Relationship between wind speed and plant hydraulics at the global scale.

Wind is an important ecological factor for plants as it can increase evapotranspiration and cause dehydration. However, the impact of wind on plant hydraulics at a global scale remains unclear. Here we compiled plant key hydraulic traits, including water potential at 50% loss of hydraulic conductivity (P), xylem-specific hydraulic conductivity (K), leaf area to sapwood area ratio (A/A) and conduit diameter (D) with 2,786 species-at-site combinations across 1,922 woody species at 469 sites worldwide and analysed their correlations with wind speed.

Visible light-driven copper vanadate/biochar nanocomposite for heterogeneous photocatalysis degradation of tetracycline: Performance, mechanism, and application of machine learning.

Water pollution caused by antibiotics is considered a major and growing issue. To address this challenge, high-performance copper vanadate-based biochar (CuVO/BC) nanocomposite photocatalysts were prepared to develop an efficient visible light-driven photocatalytic system for the remediation of tetracycline (TC) contaminated water. The effects of photocatalyst mass, solution pH, pollutant concentration, and common anions on the TC degradation were investigated in detail.

Formaldehyde-purifying air conditioner with integrated gas-phase photoelectrocatalytic system.

Developing an efficient and economical indoor air purification system for catalytic decomposition of formaldehyde is of great significance. In this work, an indoor air conditioner capable of purifying formaldehyde was designed by directly integrating defective WO/TiO nanotube catalytic fin, with both thermal conductivity and gas-phase photoelectrocatalytic (GPEC) properties, onto the condenser component. The electrochemical treatment of the catalytic fin introduced a substantial number of oxygen vacancies, resulting in a significant increase in carrier concentration and mobility to the semi-metallic level.

Water-Resistant Poly(vinyl alcohol)/ZnO Nanopillar Composite Films for Antibacterial Packaging.

To solve the problems that poly(vinyl alcohol) (PVA) easily breeds bacteria and swells in a humid environment, PVA and ZnO nanopillar (ZnO NP) components were composed to generate PVA/ZnO NP composite films via a simple combination process of blending and heat treatment in this study. Here, ZnO NPs endowed composite films with good antibacterial properties, and the etherification and dehydration of hydroxyl groups between PVA molecular chains induced by heat treatment resulted in the composite films having excellent water-swelling resistance. Most importantly, PVA/ZnO NP composite films revealed excellent tensile strength in both humid (52.

Modeling diabetes progression with risk factors: A case study in China.

Background: Approximately 537 million adults worldwide have diabetes, more than 90 % of which is type 2 diabetes mellitus (T2DM). China has the largest number of people living with diabetes. Understanding the epidemiological mechanism can guide diabetes surveillance and control.

Covalent organic frameworks hybridized polymeric high internal phase emulsions with amphiphilicity for extraction of trace bisamide insecticides in food samples.

Polymeric high internal phase emulsions decorated with covalent organic frameworks (polyHIPEs-COFs) were synthesized and used as the sorbent for cyantraniliprole and chlorantraniliprole. Pickering high internal phase emulsions stabilized by covalent organic frameworks solid particles and liquid surfactants (Span80 and polyvinylpyrrolidone) endow the composites with open-cell structures and superwettability. The amphiphilicity and open-cell structures enable rapid adsorption and desorption for cyantraniliprole and chlorantraniliprole, and the solid-phase extraction process can be completed in 5 min.

Extraction of lignin from lignocellulosic biomass (bagasse) as a green corrosion inhibitor and its potential application of composite metal framework organics in the field of metal corrosion protection.

With increasing awareness of environmental protection, additional attention has been given to environmentally friendly metal anticorrosion research. In this paper, the green organic corrosion inhibitor sodium lignosulfonate (SLS) was extracted from bagasse waste, and a Ce-MOF@SLS smart anticorrosive film containing the inhibitor was prepared on the surface of an aluminum alloy by in situ electrodeposition. The material was characterized by SEM, EDS, FT-IR, XRD and XPS, and its corrosion resistance was tested with EIS and neutral salt spray tests.

Injectable dual-network hyaluronic acid nanocomposite hydrogel for prevention of postoperative breast cancer recurrence and wound healing.

High locoregional recurrence rates and potential wound infections remain a significant challenge for postoperative breast cancer patients. Herein, we developed a dual-network hyaluronic acid (HA) nanocomposite hydrogel composed of herring sperm DNA (hsDNA) bridged methacrylated HA (HAMA) and FeMg-LDH-ppsa nanohybrid chelated catechol-modified HA (HADA) for the prevention of breast cancer recurrent, anti-infection, and promoting wound healing. Dynamic reversible hsDNA cross-linking combined with metal-catechol chelating renders the hydrogel injectability, rapid self-healing ability, and enhanced mechanical properties.