4,026 results match your criteria: "Guangdong Technion─Israel Institute of Technology[Affiliation]"

Spin-polarized edge states in two-dimensional materials hold promise for spintronics and quantum computing applications. Constructing stable edge states by tailoring two-dimensional semiconductor materials with bulk-boundary correspondence is a feasible approach. Recently layered NiI is suggested as a two-dimensional type-II multiferroic semiconductor with intrinsic spiral spin ordering and chirality-induced electric polarization.

View Article and Find Full Text PDF

Alleviating batch effects in cell type deconvolution with SCCAF-D.

Nat Commun

December 2024

GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macao Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Laboratory, Guangzhou Medical University, Guangzhou, China.

Cell type deconvolution methods can impute cell proportions from bulk transcriptomics data, revealing changes in disease progression or organ development. But benchmarking studies often use simulated bulk data from the same source as the reference, which limits its application scenarios. This study examines batch effects in deconvolution and introduces SCCAF-D, a computational workflow that ensures a Pearson Correlation Coefficient above 0.

View Article and Find Full Text PDF

Due to its "ferroionic" nature, CuInPS combines switchable ferroelectric polarization with highly mobile Cu ions, allowing for multiple resistance states. Its conductive mechanism involves ferroelectric switching, ion migration, and corresponding intercoupling, which are highly sensitive to external electric field. Distinguishing the dominant contribution of either ferroelectric switching or ion migration to dynamic conductivity remains a challenge and the conductive mechanism is not clear yet.

View Article and Find Full Text PDF

Concurrent Pressure-Induced Superconductivity and Photoconductivity Transitions in PbSeTe.

Adv Mater

December 2024

Academy for Advanced Interdisciplinary Studies and Department of Physics, Southern University of Science and Technology (SUSTech), Shenzhen, 518055, P. R. China.

Concurrent superconductivity and negative photoconductivity (NPC) are rarely observed. Here, the discovery in PbSeTe of superconductivity and photoconductivity transitions between positive photoconductivity (PPC) and NPC during compression is reported to ≈40 GPa and subsequent decompression, which are also accompanied by reversible structure transitions (3D Fm m ⇌ 2D Pnma ⇌ 3D Pm m). Superconductivity with a maximum T of ≈6.

View Article and Find Full Text PDF

Skull defects are common in the clinical practice of neurosurgery, and they are easily complicated by encephalitis, which seriously threatens the life and health safety of patients. The treatment of encephalitis is not only to save the patient but also to benefit the society. Based on the advantages of injectable hydrogels such as minimally invasive surgery, self-adaptation to irregularly shaped defects, and easy loading and delivery of nanomedicines, an injectable hydrogel that can be crosslinked in situ at the ambient temperature of the brain for the treatment of encephalitis caused by cranial defects is developed.

View Article and Find Full Text PDF

The treatment and repair of bone tissue damage and loss due to infection, tumours, and trauma are major challenges in clinical practice. Artificial bone scaffolds offer a safer, simpler, and more feasible alternative to bone transplantation, serving to fill bone defects and promote bone tissue regeneration. Ideally, these scaffolds should possess osteoconductive, osteoinductive, and osseointegrative properties.

View Article and Find Full Text PDF

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).

View Article and Find Full Text PDF

This study reviewed the recovery of humic substances (HS) from anaerobic digestate of sludge as a potential fertilizer, focusing on the quantification of HS, the efficiency of HS recovery, and its interaction with pollutants. The potential pitfalls of current misunderstanding for HS quantification in sludge were pointed out. HS present in sludge showed potential to be used as a fertilizer, which solubilized insoluble phosphates for enhanced soil fertility.

View Article and Find Full Text PDF

Biomimetic Active Stereo Camera System with Variable FOV.

Biomimetics (Basel)

December 2024

School of Mechanical Engineering and Automation, Harbin Institute of Technology Shenzhen, Shenzhen 518055, China.

Inspired by the biological eye movements of fish such as pipefish and sandlances, this paper presents a novel dynamic calibration method specifically for active stereo vision systems to address the challenges of active cameras with varying fields of view (FOVs). By integrating static calibration based on camera rotation angles with dynamic updates of extrinsic parameters, the method leverages relative pose adjustments between the rotation axis and cameras to update extrinsic parameters continuously in real-time. It facilitates epipolar rectification as the FOV changes, and enables precise disparity computation and accurate depth information acquisition.

View Article and Find Full Text PDF

Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury.

Drug Des Devel Ther

December 2024

Research Center of Innovation, Entrepreneurship, Minjiang University, Fuzhou, 350100, People's Republic of China.

Introduction: Acute kidney injury (AKI) is linked to high rates of mortality and morbidity worldwide thereby posing a major public health problem. Evidences suggest that ferroptosis is the primary cause of AKI, while inhibition of monoamine oxidase A(MAOA) and 5-hydroxytryptamine were recognized as the defender of ferroptosis. Curcumin (Cur) is a natural polyphenol and the main bioactive compound of , which has been found nephroprotection in AKI.

View Article and Find Full Text PDF

LDB1 establishes multi-enhancer networks to regulate gene expression.

Mol Cell

December 2024

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:

How specific enhancer-promoter pairing is established remains mostly unclear. Besides the CTCF/cohesin machinery, few nuclear factors have been studied for a direct role in physically connecting regulatory elements. Using a murine erythroid cell model, we show via acute degradation experiments that LDB1 directly and broadly promotes connectivity among regulatory elements.

View Article and Find Full Text PDF

To kill or to piggyback: Switching of viral lysis-lysogeny strategies depending on host dynamics.

Sci Total Environ

December 2024

Archaeal Biology Center, Synthetic Biology Research Center, Shenzhen Key Laboratory of Marine Microbiome Engineering, Key Laboratory of Marine Microbiome Engineering of Guangdong Higher Education Institutes, Institute for Advanced Study, Shenzhen University, Shenzhen 518055, PR China. Electronic address:

Viruses wield significant influence over microbial communities and ecosystem function in marine environments. However, the selection of viral life strategies and their impacts on microbial communities remains enigmatic. In this study, we utilized a large-scale macrocosm, established using water samples from a marine coastal region, to enable community-level investigation.

View Article and Find Full Text PDF

Facilitated transport membranes (FTMs) with an ultraselective layer prepared from amine-rich polyvinylamine (PVAm)/2-(1-piperazinyl)ethylamine salt of sarcosine (PZEA-Sar) (denoted by PM) and an amorphous dendritic cross-linked network of PVAm-functionalized poly(ethylene glycol)diglycidyl ether (PEGDGE) (named PP) were designed for CO separations. The developed membranes expedited CO transport over N through the synergistic effect from the induced CO-philic ethylene oxide groups and highly hydrophilic and polar hydroxyl groups together with the low-crystallinity PP networks, which offer a high diffusion rate for CO-amine complexes through the membrane and stabilize small molecular mobile carriers via hydrogen bonding. The best (PM/PP-10)/polysulfone (PSf) composite membranes achieved a superior CO/N selectivity of 230 (4.

View Article and Find Full Text PDF

Study on Recovery Strategy of Hearing Loss & SGN Regeneration Under Physical Regulation.

Adv Sci (Weinh)

December 2024

Department of Neurology, Aerospace Center Hospital, School of Life, Beijing Institute of Technology, Beijing, 100081, China.

The World Health Organization (WHO) reports that by 2050, nearly 2.5 billion people are expected to have some degree of hearing loss (HL) and at least 700 million will need hearing rehabilitation. Therefore, there is an urgent need to develop treatment strategies for HL.

View Article and Find Full Text PDF

Carbon nanotubes (CNTs) show great promise for microwave absorption (MA) due to their excellent electrical conductivity and lightweight properties, which are conferred by the one dimensional hollow tubular structure. However, the ambiguous intrinsic motivations behind the formation of CNTs and the intricate growth processes have resulted in a lack of a systematic methodology for precisely controlling their electromagnetic properties. Herein, a flexible CNTs regulation strategy is designed to develop, with the core focus being the directional growth of carbon atoms and the differential catalysis of metal sources.

View Article and Find Full Text PDF

Author Correction: π-HuB: the proteomic navigator of the human body.

Nature

December 2024

State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.

View Article and Find Full Text PDF

Bright NIR-II emissive cyanine dye-loaded lipoprotein-mimicking nanoparticles for fluorescence imaging-guided and targeted NIR-II photothermal therapy of subcutaneous glioblastoma.

J Nanobiotechnology

December 2024

School of Science, Shenzhen Key Laboratory of Advanced Functional Carbon Materials Research and Comprehensive Application, Harbin Institute of Technology, Shenzhen, 518055, China.

Cyanine dye-containing nanoparticles have widely been used in "all-in-one" NIR fluorescence imaging (FI)-guided photothermal therapy (PTT) because of their intrinsically large extinction coefficient and available physical and chemical modulation methods to tune absorption and emission wavelengths. The combination of good brightness and excellent tumor-targeting capacity is the key to realize efficient NIR-II FI-guided PTT. In this study, by covalently decorating NIR-II absorptive cyanine dyes with bulky AIE motify, we demonstrate how steric hindrance suppresses π-π stacking-induced fluorescence quenching and contributes to the good brightness of NIR-II FI of subcutaneous glioblastoma.

View Article and Find Full Text PDF

Chlorine and UV combination sequence: Effects on antibiotic resistance control and health risks of ARGs.

J Environ Manage

December 2024

Tianjin Key Laboratory of Clean Energy and Pollution Control, School of Energy and Environmental Engineering, Hebei University of Technology, Tianjin, 300401, China. Electronic address:

The effective control of antibiotic resistance in aquatic environments is urgent. The combined chlorine and UV processes (Cl-UV, UV/Cl, and UV-Cl) are considered potential control processes for controlling antibiotic resistance. This study compared the effectiveness of these three processes in real water bodies and the potential health risks associated with antibiotic resistance genes (ARGs) after treatments.

View Article and Find Full Text PDF

Systematic evaluations of receptor models in source apportionment of particulate solids in road deposited sediments: A practical application for tracking heavy metal sources on urban road surfaces.

J Hazard Mater

December 2024

Guangdong Basic Research Center of Excellence for Ecological Security and Green Development, Guangdong Provincial Key Laboratory of Water Quality Improvement and Ecological Restoration for Watersheds, School of Ecology, Environment and Resources, Guangdong University of Technology, Guangzhou 510006, China.

Receptor models have been widely used to identify pollution sources in the urban environment. However, evaluating the accuracy of source apportionment results for road deposited sediments (RDS) using these models has not been the focus of previous studies. This study compared canonical receptor models, i.

View Article and Find Full Text PDF

Multidirectional Sliding Ferroelectricity of Rhombohedral-Stacked InSe for Reconfigurable Photovoltaics and Imaging Applications.

Adv Mater

December 2024

Centre for Quantum Physics, Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement (MOE), School of Physics, Beijing Institute of Technology, Beijing, 100081, China.

Through the stacking technique of 2D materials, the interfacial polarization can be switched by an interlayer sliding, known as sliding ferroelectricity, which is advantageous in ultra-thin thickness, high switching speed, and high fatigue resistance. However, uncovering the relationship between the sliding path and the polarization state in rhombohedral-stacked materials remains a challenge, which is the key to 2D sliding ferroelectricity. Here, layer-dependent multidirectional sliding ferroelectricity in rhombohedral-stacked InSe (γ-InSe) is reported via dual-frequency resonance tracking piezoresponse force microscopy and conductive atomic force microscopy.

View Article and Find Full Text PDF

A feasible regulation strategy for conjugation of antibiotic resistance genes based on different bacterial quorum sensing inhibition methods.

Water Res

December 2024

State Key Laboratory of Urban Water Resource and Environment, School of Civil and Environmental Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, Guangdong, 518055, PR China; State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin, Heilongjiang, 150090, PR China.

The dissemination of antibiotic resistance genes (ARGs) poses global environmental issues, and plasmid-mediated conjugation contributes substantially to the spread of ARGs. Quorum sensing (QS), an important cell-cell communication system that coordinates group behaviors, has potential as a feasible regulation pathway to inhibit the conjugation process. We examined the promoting effects of QS signal on conjugation, and this study is the first to report that QS inhibitors 2(3H)-benzofuranone and acylase I effectively repressed conjugation frequency of RP4 plasmid to 0.

View Article and Find Full Text PDF

Complex networks are susceptible to contagious cascades, underscoring the urgency for effective epidemic mitigation strategies. While physical quarantine is a proven mitigation measure for mitigation, it can lead to substantial economic repercussions if not managed properly. This study presents an innovative approach to selecting quarantine targets within complex networks, aiming for an efficient and economic epidemic response.

View Article and Find Full Text PDF

Near-Infrared Light Driven Reversible Photoelectrochemical Bioassay by S-Scheme All-Polymer Blends for Acetylcholinesterase Activity Monitoring.

Nano Lett

December 2024

Hubei Key Laboratory of Plasma Chemistry and Advanced Materials, Hubei Engineering Technology Research Center of Optoelectronic and New Energy Materials, Wuhan Institute of Technology, Wuhan 430205, P. R. China.

Photoelectrochemical (PEC) biosensing, recognized for its heightened sensitivity, faces limitations in its application for diagnosis due to the inefficiency of UV-visible light-driven photoactive materials in nontransparent biological samples. In this study, we investigate the potential of an S-scheme all-polymer heterojunction comprising a prototype nonfullerene polymeric acceptor (PYIT) and carbon nitride to develop a near-infrared (NIR) light-driven PEC biosensor for monitoring acetylcholinesterase activity in nontransparent human whole blood. The distinct molecular structure of PYIT enables efficient light absorption in the NIR region, enhancing sensitivity in nontransparent biological samples.

View Article and Find Full Text PDF

This review article presents a detailed examination of the integral role that electrochemical detection of extracellular vesicles (EVs) plays, particularly focusing on the potential application for early disease diagnostics through EVs biomarker analysis. Through an exploration of the benefits and challenges presented by electrochemical detection vetted for protein, lipid, and nucleic acid biomarker analysis, we underscore the significance of these techniques. Evidence from recent studies renders this detection modality imperative in identifying diverse biomarkers from EVs, leading to early diagnosis of diseases such as cancer and neurodegenerative disorders.

View Article and Find Full Text PDF

A bismuth oxide-modified copper host achieving bubble-free and stable potassium metal batteries.

Chem Sci

December 2024

Siyuan Laboratory, Guangdong Provincial Engineering Technology Research Center of Vacuum Coating Technologies and New Energy Materials, College of Physics & Optoelectronic Engineering, Department of Physics, Jinan University Guangzhou 510632 China

Due to the minimal electrochemical oxidation-reduction potential, the potassium (K) metal anode has emerged as a focal in K-ion batteries. However, the reactivity of the K metal anode leads to significant side reactions, particularly gas evolution. Mitigating gas generation from K metal anodes has been a persistent challenge in the field.

View Article and Find Full Text PDF