10 results match your criteria: "Guangdong Provincial Center for Skin Diseases and STD Control.[Affiliation]"

Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study.

Lancet Microbe

September 2024

Department of Medicine, Division of Infectious Diseases, Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Institute for Global Health and Infectious Diseases, Infectious Diseases Epidemiology and Ecology Laboratory, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Article Synopsis
  • The study focuses on understanding the molecular epidemiology of Treponema pallidum subspecies pallidum (TPA) to aid in the development of a global syphilis vaccine by analyzing clinical data and specimens from early syphilis patients across multiple countries.* -
  • Enrolling 233 patients with primary and secondary syphilis from China, Colombia, Malawi, and the USA, researchers utilized whole-genome sequencing (WGS) to study TPA strains, revealing important demographic information and a significant presence of HIV co-infections among participants.* -
  • The findings highlighted a dominance of SS14-lineage strains with geographical distribution patterns, confirming genetic differences in the Nichols-lineage strains, which could inform future vaccine strategies and
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Article Synopsis
  • Mycoplasma genitalium (MG) is linked to urogenital infections and reproductive issues but is not routinely tested in China; this study examines MG prevalence in patients from a Guangzhou STI clinic from Jan 2017 to May 2018.* -
  • Among 678 patients tested, MG was found in 7.2%, with a higher rate (14.2%) among symptomatic individuals; only one-third of those infected reported any symptoms.* -
  • The study suggests that routine testing for MG in symptomatic patients could be beneficial, and more research is needed to inform testing guidelines for this infection in China.*
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Determining the in vitro susceptibility of Neisseria gonorrhoeae isolates from 8 cities in Guangdong Province through an improved microdilution method.

Diagn Microbiol Infect Dis

December 2018

Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong 510091, China; Guangdong Provincial Dermatology Hospital, Guangzhou, Guangdong 510091, China; Guangdong Provincial Center for Skin Diseases and STD Control, Guangzhou, Guangdong 510091, China. Electronic address:

A microdilution method for the antibiotic susceptibility testing of Neisseria gonorrhoeae was established and improved, and the antibiotic resistance of N. gonorrhoeae samples isolated from 8 cities of Guangdong in 2016 was determined. The improved microdilution method was compared with the agar dilution method recommend by the World Health Organization (WHO) Western Pacific Region by testing the susceptibility of 100 clinical N.

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Overcoming barriers to health-care access: A qualitative study among African migrants in Guangzhou, China.

Glob Public Health

October 2016

a Department of Behavioral Sciences and Health Education , Rollins School of Public Health, Emory University, Atlanta , GA , USA.

Guangzhou is China's third most populous city, and the region's burgeoning manufacturing economy has attracted many young African businessmen and entrepreneurs to the city. The aims of this study were to examine strategies that African migrants in Guangzhou have adopted in response to health-care barriers, and explore their perceptions of how to address their needs. Twenty-five semi-structured interviews and two focus groups were conducted among African migrants residing in Guangzhou, China.

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Association of the in vitro susceptibility of clinical isolates of chlamydia trachomatis with serovar and duration of antibiotic exposure.

Sex Transm Dis

March 2015

From the *Guangdong Provincial Dermatology Hospital/Guangdong Provincial Center for Skin Diseases and STD Control, Guangzhou, China; and †Xiangya School of Medicine, Central South University, Changsha, China.

Background: The presence of persistent Chlamydia trachomatis infection after treatment does not always correlate with in vitro susceptibility testing.

Methods: The in vitro minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of azithromycin, clarithromycin, roxithromycin, doxycycline, tetracycline, ofloxacin, and penicillin were tested against 61 clinical isolates of C. trachomatis on 6 serovars, and the MIC/MBC of azithromycin and ofloxacin at different points in time after antibiotic administration to infected cultures.

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HIV prevalence, incidence and risk behaviours among men who have sex with men in Yangzhou and Guangzhou, China: a cohort study.

J Int AIDS Soc

March 2015

National Center for STD Control and Prevention, China Centers for Diseases Control and Prevention, Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China.

Introduction: In China, the prevalence and incidence of HIV among men who have sex with men (MSM) in large-sized cities have drawn much attention. In contrast, there has been a paucity of research focussing on the sexual health of MSM of medium-sized cities. This study fills this important gap in the knowledge by investigating the sexual health of MSM in a medium-sized city (Yangzhou) and a large-sized city (Guangzhou).

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Antibiotic susceptibility of Neisseria gonorrhoeae in Guangzhou during 2002-2011 showed that resistance to penicillin and ciprofloxacin was high, while ceftriaxone remained effective although there was a trend towards reduced sensitivity.

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Despite expanding sexually transmitted epidemics in South China, the majority of patients presenting to sexually transmitted infection (STI) clinics are not routinely screened for HIV infection. Identifying barriers to offering HIV testing among STI care providers is an important public health priority. The aim of this study was to investigate the frequency of offering HIV testing among STI care providers in South China and reported physician barriers to offering HIV testing.

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Background: Expanding HIV testing is important among individuals at increased risk for sexual HIV transmission in China, but little is known about prior HIV testing experiences among sexually transmitted disease (STD) patients.

Methods: This cross-sectional study of 1792 outpatients from 6 public STD clinics in Guangdong Province recorded detailed information about ever having been tested for HIV infection in addition to sociodemographic variables, health seeking, clinical STD history, and HIV stigma using a validated survey instrument.

Results: A total of 456 (25.

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Background: HIV testing is still stigmatized among many high-risk groups in China, whereas routine syphilis testing has been widely accepted at sexually transmitted infection (STI) clinics. This project used the platform of a rapid syphilis screening test to expand HIV test uptake. The objective of this study was to use multilevel modeling to analyze determinants of syphilis and HIV-testing uptake at STI clinics in China.

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