4 results match your criteria: "Guangdong Provincal Hospital of Traditional Chinese Medicine[Affiliation]"
MEK5 overexpression is associated with the occurrence and development of colorectal cancer.
BMC Cancer
May 2016
Department of Gastrointestinal Surgery, Guangdong Provincal Hospital of Traditional Chinese Medicine, Guangdong, 510120, China.
Background: Mitogen/extracellular signal-regulated kinase kinase-5 (MEK5) has been confirmed to play a pivotal role in tumor carcinogenesis and progression. However, few studies have investigated the role of MEK5 in colorectal cancer (CRC).
Methods: MEK5 expression was determined by immunohistochemistry (IHC) in tissue microarrays (TMAs) containing 2 groups of tissues, and western blotting was used to confirm MEK5 expression in 8 cases of primary CRC tissues and paired normal mucosa.
Effects of Electro-Acupuncture at Zusanli, Guanyuan for Sepsis Patients and Its Mechanism through Immune Regulation.
Chin J Integr Med
March 2016
Intensive Care Unit, Guangdong Provincal Hospital of Traditional Chinese Medicine, Guangzhou, 510006, China.
Objective: To evaluate the effect of electro-acupuncture on Zusanli (ST 36), Guanyuan (RN 4) in patients with sepsis, and explore its mechanism in term of immune regulation.
Methods: In this prospective randomized controlled trial, 60 patients with sepsis were randomly assigned to the control group and the intervention group equally by block randomization. Patients in the control group received routine treatment and those in the intervention group received electro-acupuncture at bilateral Zusanli and Guanyuan in addition to routine treatment, respectively.
Mitogen/extracellular signal-regulated kinase kinase-5 promoter region polymorphisms affect the risk of sporadic colorectal cancer in a southern Chinese population.
DNA Cell Biol
March 2012
Guangdong Provincal Hospital of Traditional Chinese Medicine (the postdoctoral mobile research station of Guangzhou University of Traditional Chinese Medicine), Guangdong, China.
Article Synopsis
- This study investigates the role of the MEK5 gene promoter variants in the susceptibility to sporadic colorectal cancer (CRC), focusing on two specific polymorphisms (rs7172582C>T and rs3743354T>C).
- The research involved 737 CRC patients and 703 healthy controls, revealing that the rs3743354 CC genotype is linked to a significantly lower risk of CRC compared to the TT genotype.
- Environmental factors like smoking and drinking were found to interact with the rs3743354 variant, further lowering CRC risk, while no significant association was seen with the rs7172582C>T polymorphism.
[Dynamic observation IgG and IgM antibodies in patients with severe acute respiratory syndrome].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
October 2003
Clinical Laboratory, Ersha Island Branch Guangdong Provincal Hospital of Traditional Chinese Medicine, Guangzhou 510105, Guangdong, China.
Objective: To observe IgG and IgM antibodies in patients with severe acute respiratory syndrome (SARS) and to explore their significance.
Methods: IgG and IgM antibodies were detected in SARS Patients in the first, recovery and follow-up stages, the front healthy doctors and nurses and healthy volunteers with indirect enzyme-linked immunoadsorbent assay.
Results: The positive ratio of IgG was higher than that of IgM in SARS patients during the first stage.