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Guangdong Medical University Guangdong[... Publications | LitMetric

4 results match your criteria: "Guangdong Medical University Guangdong[Affiliation]"

Article Synopsis
  • This study evaluates how effective strain parameters from cardiovascular magnetic resonance imaging are in diagnosing acute myocarditis in different patient groups based on ejection fraction.
  • It involves 65 patients with acute myocarditis and 25 healthy controls, separating patients into those with preserved and reduced ejection fraction, finding significant differences in strain parameters compared to controls.
  • Key findings include high diagnostic accuracy for distinguishing preserved ejection fraction patients from controls, indicating that specific strain measurements correlate with myocardial injury markers like troponin I.
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Nucleus-selective codelivery of proteins and drugs for synergistic antitumor therapy.

Chem Sci

September 2022

Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University Chongqing 401331 China

Subcellular organelle targeted transport is of great significance for accurately delivering drugs to active sites for better pharmacological effects, but there are still a lot of challenges due to transport problems. In addition, the killing effect of one kind of drug on cells is limited. Therefore, it is necessary to develop a multifunctional nanoplatform that can co-deliver synergistic therapeutic agents.

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Article Synopsis
  • - Winer's dilated pore is a rare type of skin tumor that appears as a large blackhead, typically found on the face, neck, and upper trunk in adults.
  • - A case study discusses a 57-year-old woman who developed multiple painless black spots on her labia majora, which were confirmed as Winer's dilated pores through histopathology.
  • - The study suggests that electrocautery could be an effective treatment for these lesions, noting that this patient may be the first reported case of multiple vulvar Winer's dilated pores.
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Airway remodeling can lead to irreversible airflow obstruction and persistent airway hyper-responsiveness, which is the pathological basis of refractory asthma. To investigate the preventive effect of protocatechuic aldehyde on airway remodeling in asthmatic mice by lung morphometry methods. BALB/c mice were used to establish model of airway remodeling by ovalbumin (OVA) inhalation.

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