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Int J Clin Exp Pathol
March 2016
Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College 1 Xincheng Road, Dongguan 523808, China ; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics 1 Xincheng Road, Dongguan 523808, China.
Ulcerative colitis (UC) is an inflammatory bowel disease, and its pathogenesis involves a variety of genetic, environmental, and immunological factors such as T helper cells and their secreted cytokines. B and T lymphocyte attenuator (BTLA) is an immunoregulatory receptor that has a strong suppressive effect on T-cell function. However the role of BTLA in UC remains poorly understood.
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