Prevalence of HIV-1 drug resistance in treated patients with viral load >50 copies/mL: a 2014 French nationwide study.

Background: Surveillance of HIV-1 resistance in treated patients with a detectable viral load (VL) is important to monitor, in order to assess the risk of spread of resistant viruses and to determine the proportion of patients who need new antiretroviral drugs with minimal cross-resistance.

Methods: The HIV-1 protease and reverse transcriptase (RT) and integrase genes were sequenced in plasma samples from 782 consecutive patients on failing antiretroviral regimens, seen in 37 specialized centres in 2014. The genotyping results were interpreted using the ANRS v24 algorithm.

Impact of safety devices for preventing percutaneous injuries related to phlebotomy procedures in health care workers.

Background: Use of protective devices has become a common intervention to decrease sharps injuries in the hospitals; however few studies have examined the results of implementation of the different protective devices available.

Objective: To determine the effectiveness of 2 protective devices in preventing needlestick injuries to health care workers.

Methods: Sharps injury data were collected over a 7-year period (1993-1999) in a 3600-bed tertiary care university hospital in France.