A qualitative study exploring community pharmacists' perceptions and experiences with information transfer from Queensland health hospitals during patients' transitions of care.

Objective: This study explored community pharmacists' experiences and perceptions of information transfer from Queensland health hospitals for patients during transitions of care and the current utilization of electronic medical records for accessing patient information.

Methods: Qualitative methodology was used involving in-depth semi-structured interviews with community pharmacists to explore their experiences and perceptions with information transfer during patients' transitions of care. Purposive sampling was used to ensure the participation of community pharmacists who had experience with the medication management of patients discharged from Queensland health hospitals.

A mitochondrial nexus in major depressive disorder: Integration with the psycho-immune-neuroendocrine network.

Nervous system processes, including cognition and affective state, fundamentally rely on mitochondria. Impaired mitochondrial function is evident in major depressive disorder (MDD), reflecting cumulative detrimental influences of both extrinsic and intrinsic stressors, genetic predisposition, and mutation. Glucocorticoid 'stress' pathways converge on mitochondria; oxidative and nitrosative stresses in MDD are largely mitochondrial in origin; both initiate cascades promoting mitochondrial DNA (mtDNA) damage with disruptions to mitochondrial biogenesis and tryptophan catabolism.