2 results match your criteria: "Gregorio Marañón Research Institute (IiSGM) and University Hospital[Affiliation]"
SARS-CoV2 Infection During Pregnancy Causes Persistent Immune Abnormalities in Women Without Affecting the Newborns.
Front Immunol
August 2022
Immunology Section, Laboratory of ImmunoBiology Molecular, Hospital General Universitario Gregorio Marañón (HGUGM), HIV-HGM BioBank, Madrid, Spain.
SARS-CoV2 infection in pregnancy and exposed newborns is poorly known. We performed a longitudinal analysis of immune system and determined soluble cytokine levels in pregnant women infected with SARS-CoV2 and in their newborns. Women with confirmed SARS-CoV2 infection and their exposed uninfected newborns were recruited from Hospital General Universitario Gregorio Marañón.
View Article and Find Full Text PDFInnate and adaptive abnormalities in youth with vertically acquired HIV through a multicentre cohort in Spain.
J Int AIDS Soc
October 2021
Infectious Diseases in Paediatric Population, Gregorio Marañón Research Institute (IiSGM) and University Hospital, Madrid, Spain.
Article Synopsis
- Youth with vertically acquired HIV (YWVH) show immune abnormalities despite being on antiretroviral treatment (ART), especially with heightened T-cell activation and exhaustion levels.
- A study comparing YWVH to HIV-negative youth found strong correlations between immune activation markers and the CD4/CD8 ratio, suggesting this ratio may help in tracking disease progression.
- Overall, ART appears to only partially restore normal immune function in YWVH, emphasizing the need for ongoing monitoring and adaptation of treatment strategies.