36 results match your criteria: "Granulosis Rubra Nasi"

Granulosis rubra nasi from plastic surgery perspective.

J Surg Case Rep

September 2024

Plastic and Reconstructive Surgery Section, Department of Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

Article Synopsis
  • Granulosis rubra nasi (GRN) is a genetic disorder causing facial redness, sweating, and papules, primarily affecting the eccrine glands, and it's often diagnosed based on clinical observation.
  • The main approach to managing GRN involves educating patients about its benign nature, while treatments like Botox and corticosteroid injections have been proposed, but no definitive cure exists.
  • A case study of a 26-year-old man with chronic nose sweating was treated successfully with Botox; however, a proposed technique involving undercutting the glands during rhinoplasty was declined by the patient, emphasizing the need for caution in high-risk individuals to prevent skin complications.
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Article Synopsis
  • - Granulosis rubra nasi (GRN) is a rare skin condition that affects sweat glands and has no known cause, typically appearing in early childhood.
  • - Symptoms include excessive sweating, redness, small bumps, pus-filled spots, and blisters on the face, but the condition is painless and often resolves by puberty.
  • - A case study is presented involving a 38-year-old woman, detailing unique site and dermoscopy findings that haven't been documented before.
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Granulosis Rubra Nasi: A Case Report and Brief Review of the Literature.

Case Rep Dermatol Med

January 2023

Department of Dermatovenereology, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia.

Granulosis rubra nasi is a rare autosomal dominant disease of the eccrine glands. It is clinically characterized by mid-face hyperhidrosis, most prominent at the tip of the nose, and dark erythematous papules on the nose, cheeks, chin, and upper lip. Although it commonly occurs in childhood, it can also occur in adults.

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Article Synopsis
  • Facial papules, common in various skin conditions, were studied in patients with a specific grouped eruption primarily on the nose and cheeks, which had not been well defined before.
  • In a group of 11 patients, average age 29, asymptomatic skin-colored to slightly red papules were noted, along with histological findings of lymphoid infiltrate and epidermal atrophy.
  • The eruption, characterized as a chronic condition, suggests a new distinct clinicopathological entity potentially linked to actinic lichen nitidus or a variant of polymorphous light eruption.
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Article Synopsis
  • Granulosis Rubra Nasi (GRN) is a rare skin disorder affecting the sweat (eccrine) glands, typically causing excessive sweating.
  • It manifests as hyperhidrosis primarily on the tip of the nose, often accompanied by redness (erythema) around the nose, cheeks, chin, and upper lip.
  • Although commonly seen in children, GRN can also occur in adults; this report highlights an unusual case in an adult patient with unique histopathological features.
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Ectodermal Dysplasia-Skin Fragility Syndrome: A Rare Case Report.

Indian J Dermatol

August 2015

Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Article Synopsis
  • * Only 12 cases of this disorder have been documented, highlighting its rarity.
  • * A notable case involves a 12-year-old boy who was healthy at birth but later experienced skin fragility, hair and nail deformities, dental problems, and abnormal sweating, without any systemic health issues.
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Granulosis rubra nasi.

Indian Dermatol Online J

July 2013

Department of Skin and STD, Sree Balaji Medical College and Hospital, Chromepet, Chennai, India.

Article Synopsis
  • Granulosis rubra nasi is a rare genetic condition linked to the eccrine glands, causing excessive sweating (hyperhidrosis) primarily on the face, especially the tip of the nose.
  • A 27-year-old male patient exhibited symptoms of intense sweating and redness on the nose, cheeks, chin, and upper lip, along with small raised blood vessels (telangiectatic vesicles).
  • This case is noteworthy due to its rarity and the fact that it's the first reported instance of granulosis rubra nasi in Indian patients.
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Article Synopsis
  • - Josef Jadassohn was a groundbreaking dermatologist who introduced the patch test to identify hypersensitivity reactions and provided original descriptions of skin conditions like nevus sebaceous and pachyonychia congenita.
  • - He also edited the "Handbuch der Haut- und Geschlechtskrankheiten," which became the most thorough dermatology textbook ever published.
  • - Jadassohn mentored several notable students who became significant figures in dermatology, including Felix Lewandowsky and Marion B. Sulzberger.
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Article Synopsis
  • A 20-year-old girl presented with asymptomatic reddish vesicles on her face for four years, worsening in summer and associated with localized sweating.
  • Histopathological analysis revealed mononuclear cell infiltration and dilated capillaries around the sweat glands, leading to a diagnosis of Granulosis rubra nasi (GRN).
  • While GRN typically resolves by puberty, this case documents its persistence into adulthood and shows an excellent response to topical tacrolimus, a treatment response not previously noted in the literature.
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Hyperhidrosis, vesicles, and papules over the nose: granulosis rubra nasi.

Indian J Dermatol Venereol Leprol

April 2016

Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, University of Delhi, Delhi, India.

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Botulinum toxin A has a wide variety of clinical applications in medical and dermatologic sciences. Nowadays, researchers introduce some other indications for botulinum toxin in cosmetic and especially noncosmetic aspects of dermatology such as medical rhinoplasty, hypertrophic scar, chemical brow lift, supraciliary wrinkles, pompholix, eccrine angiomatosis, Hailey-Hailey, dermatochalasis, lichen simplex, nosthalgia parestetica, and granulosis rubra nasi. In this general overview of the use of botulinum toxin in dermatology, an extensive literature search was carried out to updates of all dermatology-oriented experiments and clinical trials on the mentioned aspect of botulinum toxin.

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Granulosis rubra nasi.

Int J Dermatol

April 2007

Dermatology Department, UHC Med VI, Marrakech, Morocco.

Article Synopsis
  • - An 18-year-old male had red lesions on his nose for a year, which didn't get worse in sunlight and had no related family history.
  • - He experienced excessive sweating on his nose, cheeks, and upper lip, with the nose showing redness and small fluid-filled blisters.
  • - A skin biopsy revealed a specific type of immune cell infiltration around blood vessels in the affected area.
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[Granulosis rubra nasi and pheochromocytoma].

Ann Dermatol Venereol

October 1996

Clinique Dermatologique, Hôpitaux Universitaires, Strasbourg.

Article Synopsis
  • Granulosis rubra nasi is a rare skin condition characterized by red, papular lesions on the nose, often seen in children and linked to excessive sweating (hyperhidrosis).
  • A case involving a 19-year-old girl revealed that her hyperhidrosis, granulosis rubra nasi, and fast heart rate (tachycardia) were due to a noradrenalin-secreting pheochromocytoma, which was surgically removed.
  • Post-surgery, the girl experienced relief from hyperhidrosis, improvement of the nasal lesions, and normal levels of urinary catecholamines, suggesting a connection between the pheochromocytoma and the other symptoms.
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Article Synopsis
  • Granulosis Rubra Nasi is a rare skin condition found in early childhood, characterized by inflammation and hyperhidrosis (excessive sweating) on the nose.
  • The condition may present with symptoms like beads of sweat, redness, and small red bumps or comedo-like lesions.
  • It is also referred to as "Acne papulo-rosacea of the nose" due to its similar appearance to other acne-related conditions.
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