683 results match your criteria: "Granuloma Inguinale Donovanosis"
Multiple sexually transmitted infections as a presenting feature of human immunodeficiency virus/AIDS.
Indian J Sex Transm Dis AIDS
June 2024
Department of Skin and VD, SBKS Medical Institute and Research Centre, Waghodia, Gujarat, India.
Article Synopsis
- * Diagnostic tests revealed leukoplakia indicating donovanosis, while biopsy confirmed molluscum contagiosum, and blood tests were positive for HIV-1 and HSV-2.
- * The patient was treated with acyclovir and doxycycline, alongside antiretroviral therapy, showing slow improvement over 8 weeks; the case highlights the importance of tissue smears in diagnosing granuloma inguinale in immunocompromised patients.
[Tropical sexually transmitted infections Summary of the SFMTSI Scientific Day of November 9, 2023].
Med Trop Sante Int
December 2023
Sorbonne Université, Paris.
Article Synopsis
- - The rise of sexually transmitted infections (STIs) in the tropics is increasingly concerning, especially after the 2022 emergence of monkeypox, which echoes the previous spread of HIV/AIDS globally.
- - A World Health Organization (WHO) 2023 report highlights that STIs are on the rise worldwide, and antibiotic resistance is worsening, particularly for certain bacteria, while macrolide resistance has developed in the last two decades.
- - The potential for neglected tropical diseases like Zika and Ebola to be sexually transmitted after recovery raises new discussions about the use of pre-exposure prophylaxis (PrEP), especially for migrants and in Africa.
Granuloma inguinale diagnosed on the bedside.
Indian J Sex Transm Dis AIDS
December 2022
Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.
Article Synopsis
- Donovanosis is a rare bacterial infection caused by Klebsiella granulomatosis, leading to painless, bleeding ulcers and primarily found in specific regions worldwide.
- A case study was reported where a patient in a non-endemic area presented with a solitary genital ulcer, and initial tests did not identify the cause.
- After several days in the hospital, a repeat tissue smear uncovered Donovan bodies, allowing for a timely diagnosis and effective treatment.
An Ulcer by Any Other Name: Non-herpes and Non-syphilis Ulcerative Sexually Transmitted Infections.
Infect Dis Clin North Am
June 2023
Division of Infectious Diseases, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, THT 215, 1900 University Boulevard, Birmingham, AL 35294, USA.
Article Synopsis
- Ulcerative sexually transmitted infections (STIs) present a diagnostic challenge due to similar symptoms and limited testing resources, excluding herpes and syphilis.
- Despite a low prevalence and declining incidence of conditions like chancroid and granuloma inguinale, they still lead to significant health issues and higher HIV risk.
- With new threats like mpox emerging, accurate identification and treatment of these STIs is crucial for public health.
Relapsing donovanosis rhyming with unexplained decline in CD4 count in a person living with HIV/AIDS: Long-term follow up and therapeutic outcome.
Int J STD AIDS
May 2023
Department of Pathology, Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- - Donovanosis is a long-lasting sexually transmitted infection caused by the bacteria Klebsiella granulomatis, especially seen in individuals with HIV/AIDS.
- - The case study discusses a patient with relapsing donovanosis who is on second-line antiretroviral therapy and experiences fluctuating CD4 counts, linked to the worsening and eventual improvement of the infection.
- - Treatment was initially ineffective while the patient's CD4 count was low, but symptoms improved as the CD4 count recovered, highlighting the relationship between immune function and infection management.
Genital ulcers caused by sexually transmitted agents.
An Bras Dermatol
August 2022
Fundação Alfredo da Matta, Instituição ligada à Secretaria de Estado de Saúde do Governo do Estado do Amazonas, Manaus, AM, Brazil.
Article Synopsis
- - Genital ulcers (GUs) can be challenging to diagnose due to various causes, including infections from sexually transmitted infections (STIs), with the herpes simplex virus and Treponema pallidum being the most common culprits.
- - Diagnosis involves careful dermatological examination and assessment of regional lymph nodes, while molecular tests are the most reliable diagnostic methods available.
- - Immediate treatment is crucial to prevent complications and transmission; healthcare providers must also consider the psychological impact on patients, emphasizing the importance of trust and individualized care in treatment adherence.
Donovanosis in a Tunisian man: Atypical presentation and dermoscopic findings.
Indian J Dermatol Venereol Leprol
December 2021
Department of Dermatology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Granuloma inguinale in a mentally retarded girl.
Indian J Sex Transm Dis AIDS
July 2020
Department of Dermatology, Venereology and Leprosy, Sree Mookambika Institute of Medical Sciences, Kanyakumari, Tamil Nadu, India.
Sexually transmitted infections and human immunodeficiency virus coinfection: Scenario in Western India.
Indian J Sex Transm Dis AIDS
July 2020
Department of Dermatology, B. J. Medical College, Ahmedabad, Gujarat, India.
Article Synopsis
- - The study examines the relationship between sexually transmitted infections (STIs) and HIV, highlighting how co-infection can increase HIV transmission risks and alter the typical symptoms of STIs in people living with HIV/AIDS (PLHIV).
- - Conducted in a government hospital over 30 months, the research involved 484 PLHIV presenting with STIs, documenting the prevalence of various STIs, with herpes simplex virus being the most common at 24.17%.
- - Results indicate a decline in bacterial STIs and an increase in viral STIs among PLHIV, with atypical STI presentations occurring more frequently in this group compared to non-HIV-infected individuals.
Donovanosis.
An Bras Dermatol
November 2020
Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address:
Article Synopsis
- Donovanosis is a slow-developing bacterial infection primarily impacting the skin and mucous membranes around the genital area.
- It's often spread through sexual contact but has low infectivity rates.
- While long-term ulcerations can lead to malignant changes in lesions, this transformation is rare with donovanosis.
Asymptomatic Exophytic Plaques on the Penis of a Patient With HIV Infection: Answer.
Am J Dermatopathol
March 2020
Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma, Barcelona, Spain; and.
The changing epidemiology of genital ulcer disease in South Africa: has donovanosis been eliminated?
Sex Transm Infect
December 2020
STI Section, Centre for HIV & STIs, National Institute for Communicable Diseases, Johannesburg, South Africa.
Article Synopsis
- Researchers conducted a 12-year study in South Africa to investigate if donovanosis was a cause of genital ulcers of unknown origins using a specific molecular assay.
- They analyzed 974 genital ulcer specimens collected between 2007 and 2018, previously checked for common STIs, but found no evidence of donovanosis in any of the samples.
- The study concluded that donovanosis is not a significant cause of genital ulcer disease in South Africa, suggesting a decline in its prevalence.
Donovanosis in migrants: a clinical case series in an Italian dermatological hospital.
J Eur Acad Dermatol Venereol
December 2019
Dermatology Unit, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Sexually Transmitted Diseases in the Emergency Department.
Emerg Med Clin North Am
May 2019
Prisma Health, University of South Carolina School of Medicine Greenville, 701 Grove Road, Greenville, SC 29605, USA. Electronic address:
Article Synopsis
- - STDs are often overlooked, leading to serious health and financial issues, highlighting the need for better recognition and management by emergency clinicians.
- - These healthcare providers are crucial in diagnosing and treating STDs, which improves health outcomes for patients and their partners.
- - The review discusses various STDs, including their causes, history, symptoms, diagnostic methods, and treatment options, while also addressing challenges like antibiotic resistance and new infections.
[Sexually Transmitted Infections in the Tropics].
Hautarzt
November 2018
Department of Dermatology, Preah Kossamak-Hospital, BP 1006, Phnom Penh, Kambodscha.
Article Synopsis
- Sexually transmitted infections (STIs) like chlamydia, gonorrhea, syphilis, and trichomoniasis affect around 500 million people annually, with 75% of cases occurring in tropical regions of Latin America, sub-Saharan Africa, and South and Southeast Asia.
- Tropical STIs, including chancroid, lymphogranuloma venereum (LGV), and granuloma inguinale, are primarily found in hot, humid climates characterized by poverty and underdevelopment, leading to increased risks of skin ulcerations and HIV transmission.
- To reduce the risk of contracting these infections, it is crucial to avoid risky sexual behaviors and use condoms consistently.
Donovanosis in a child victim of sexual abuse: response to doxycycline treatment.
An Bras Dermatol
September 2018
Laboratory of Pathology, Santa Casa de São Paulo, São Paulo (SP), Brazil.
Article Synopsis
- - Donovanosis is a chronic infection caused by Klebsiella granulomatis, affecting skin and mucous membranes, primarily in genital and inguinal areas.
- - The disease, also known as venereal granuloma, is primarily found in tropical and subtropical regions and is often linked to sexual transmission.
- - A case study is shared about an 11-year-old girl with a history of chronic sexual abuse who was diagnosed with donovanosis and successfully treated with doxycycline.
2018 UK national guideline for the management of donovanosis.
Int J STD AIDS
September 2018
3 The Northern Sexual Health, Contraception and HIV Service, The Hathersage Centre, Manchester, UK.
Article Synopsis
- The guideline aims to aid in the diagnosis and management of donovanosis, a rare sexually transmitted infection, specifically targeting UK Sexual Health service professionals.
- It focuses on individuals over 16 showing possible symptoms and incorporates findings from a recent literature review since the last guideline in 2011.
- The updated review reveals limited new developments, primarily highlighting unusual presentations of the infection rather than significant advancements in treatment or understanding.
Usefulness and Utility of NACO Regime in the Management of Sexually Transmitted Infections: A Pilot Study.
Indian J Dermatol
January 2017
Department of Dermatology, Bankura Sammilani Medical College, Bankura, West Bengal, India.
Article Synopsis
- The study evaluates the effectiveness of syndromic diagnosis for sexually transmitted infections (STIs) by comparing it with etiological diagnoses in a sample of 308 patients over nine months.
- Results indicated that a significant portion of cases lacked clear etiological identification, particularly in syndromes related to genital ulcers and vaginal discharge.
- The conclusion highlights that validation of syndromic diagnosis is limited, with only about one-third of cases being accurately diagnosed, especially in complex conditions like vaginal discharge where multiple causes overlap.
Donovanosis With Bowen Disease.
Skinmed
July 2019
Silver Oaks Multispecialty Hospital, Mohali, Punjab, India.
Article Synopsis
- A 45-year-old farmer has been experiencing scrotal ulcers and plaques for 4 to 5 years, which originated from a small lesion on his penis that initially improved with treatment.
- After a brief period of healing, he developed new lesions on the scrotum that progressed to painful ulcers, despite attempts to treat them with various medications and topical products.
- Medical examination revealed nontender ulcers with specific characteristics and surrounding nodules, but there were no signs of enlarged lymph nodes, indicating a localized issue.
Tuberculosis of Glans Penis- A Rare Presentation.
J Clin Diagn Res
December 2016
Professor, Department of Surgery, Madurai Medical College, Madurai, Tamil Nadu, India .
Article Synopsis
- - Tuberculosis (TB) of the penis is an uncommon condition, even in countries with higher rates of TB.
- - It can occur as either a primary infection or secondary to pulmonary TB, often resembling other serious conditions like penile cancer or herpes.
- - A case involving a 57-year-old man, initially suspected to have penile cancer due to an ulcerative growth, was actually diagnosed with penile TB after a biopsy and confirmed by a chest X-ray.
Granulomatous & histiocytic dermatitides.
Semin Diagn Pathol
May 2017
Section of Dermatopathology, Division of Surgical & Cytological Pathology, University of Virginia Medical Center, Charlottesville, VA, USA. Electronic address:
Article Synopsis
- - Granulomas of the skin can be categorized as either infectious or non-infectious and may contain areas of necrosis or necrobiosis, necessitating histochemical analysis for identifying responsible infectious agents like mycobacteria, fungi, treponema, or parasites.
- - Non-infectious granulomas can be further divided into necrobiotic/necroting types such as granuloma annulare and rheumatoid nodules, and non-necrobiotic types like sarcoidosis and foreign-body reactions.
- - There are also unique dermatological conditions that involve histiocytic reactions without granuloma formation, such as cutaneous malakoplakia and leprosy, indicating a varied response to infections in the skin.
[Anorectal STD].
Ann Dermatol Venereol
November 2016
Service de dermatologie, hôpital Saint-André, CHU, 1, rue Jean-Burguet, 33000 Bordeaux, France.
[Donovanosis (granuloma inguinale)].
Ann Dermatol Venereol
November 2016
Centre clinique et biologique des MST, hôpital Saint-Louis, 42, rue Bichat, 75010 Paris, France.