287 results match your criteria: "Graduate school of Tianjin Medical University[Affiliation]"

To investigate the relationship between the Chinese Visceral Adiposity Index (CVAI) and the risk of developing Benign Prostatic Hyperplasia (BPH). Using data from the China Health and Retirement Longitudinal Study (CHARLS), we included 3,295 men aged 45 years and older. Multivariate logistic regression and restricted cubic spline models were employed to analyze the association between CVAI and the risk of BPH.

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Evaluation of the Therapeutic Effect of Decompression with or without Fusion on Lumbar Spinal Stenosis Caused by Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis.

World Neurosurg

December 2024

Graduate School of Tianjin Medical University, Tianjin, China; Department of Spinal Surgery, Tianjin Union Medical Center, Tianjin, China; Graduate School of Tianjin University of Traditional Chinese Medicine, Tianjin, China; Tianjin Institute of Spinal Surgery, Tianjin, China. Electronic address:

Objective: As a common clinical disease, lumbar spinal stenosis (LSS) is currently the preferred surgical treatment, and there are various opinions. We conducted a study on whether fusion should be performed simultaneously with decompression for LSS caused by low-grade degenerative lumbar spondylolisthesis and compared the efficacy and safety of the 2 surgeries.

Methods: We conducted literature searches on Cochrane Library, Embase, PubMed, Scopus, and China National Knowledge Infrastructure databases to search for randomized controlled trials and observational studies that compared decompression alone and decompression plus fusion in the treatment of LSS with low-grade lumbar spondylolisthesis.

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Background: Prostate cancer's complex interplay with the immune microenvironment prompted an investigation into immune-related pathogenic mechanisms and potential therapeutic targets.

Methods: Within the GSE176031 data set, Seurat meticulously dissected single-cell profiles from radical prostatectomy patients. Leveraging CellMarker and SingleR cell identities were precisely annotated.

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Early diagnostic value of home video-based machine learning in autism spectrum disorder: a meta-analysis.

Eur J Pediatr

November 2024

Tianjin Pediatric Research Institute; Tianjin Key Laboratory of Birth Defects for Prevention and Treatment, Tianjin Children's Hospital (Children's Hospital, Tianjin University), No. 238 Longyan Road, Tianjin, 300134, China.

Unlabelled: Machine learning (ML) based on remote video has shown ideal diagnostic value in autism spectrum disorder (ASD). Here, we conducted a meta-analysis of the diagnostic value of home video-based ML in ASD. Relevant articles were systematically searched in PubMed, Cochrane, Embase, and Web of Science from inception to September 2023 with no language restriction, and the literature search was updated in September 2024.

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Lipid-lowering drugs and risk of rapid renal function decline: a mendelian randomization study.

BMC Med Genomics

October 2024

Department of Cardiology, Tianjin Chest Hospital, Tianjin University, Tianjin, 300222, China.

Background: Chronic kidney disease (CKD) patients face the risk of rapid kidney function decline leading to adverse outcomes like dialysis and mortality. Lipid metabolism might contribute to acute kidney function decline in CKD patients. Here, we utilized the Mendelian Randomization approach to investigate potential causal relationships between drug target-mediated lipid phenotypes and rapid renal function decline.

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Chest radiography (CXR) is commonly used for diagnosing childhood pneumonia, but concerns about radiation exposure have raised interest in using radiation-free lung ultrasound (LUS) as an alternative imaging modality. Therefore, we designed this meta-analysis to compare the accuracy of LUS and CXR for diagnosing childhood pneumonia. We searched 8 databases and 1 clinical trial registry for studies published from inception to March 2023.

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Psoriasis is a chronic inflammatory skin disease, the etiology of which has not been fully elucidated, in which CD8 T cells play an important role in the pathogenesis of psoriasis. However, there is a lack of in-depth studies on the molecular characterization of different CD8 T cell subtypes and their role in the pathogenesis of psoriasis. This study aims to further expound the pathogenesy of psoriasis at the single-cell level and to explore new ideas for clinical diagnosis and new therapeutic targets.

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U-shaped kirschner wire transfixation: effective treatment for Skier's thumb.

BMC Surg

March 2024

Department of Orthopaedic, Tianjin Hospital, Jiefang South Road, Hexi District, Hospital, Tianjin, 300211, P. R. China.

Article Synopsis
  • Skier's thumb is an injury affecting the thumb's ulnar collateral ligament, often leading to joint instability and bone fragmentation.
  • This study aimed to compare two surgical methods for treating skier's thumb: the traditional Kirschner wire fixation and the U-shaped Kirschner wire fixation.
  • Results showed that the U-shaped method led to less pain, better functional outcomes, and fewer complications compared to the traditional method, making it a safer and more effective treatment option.
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Background: Contrast-induced nephropathy (CIN) is one of the most common complications after coronary stent implantation due to the extensive development of coronary catheterization technology. Compound Danshen dripping pills (CDDP) are clinically used as cardiovascular drugs, relieving systemic inflammatory response. Previous studies have observed that CDDP can decrease CIN incidence after coronary stent implantation with uncertain effectiveness.

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The objective of this study was to analyze the effects of annulus fibrosus incision and foraminoplasty on lumbar biomechanics during posterior lateral approach translaminar percutaneous endoscopic lumbar discectomy (PELD) using a lumbar 4/5 segment model and three-dimensional finite element analysis (FEA). We created a model of the L4 to L5 segment and performed simulated foraminoplasty, annulus fibrosus incision, and a combined operation. The models were tested under six working conditions, and we recorded the deformation and equivalent strain/stress of each group.

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Establishment and validation of symptomatic patients colorectal screening score for predicting colorectal neoplasia risk.

J Dig Dis

November 2023

Tianjin Key Laboratory of Digestive Diseases, Department of Gastroenterology and Hepatology, Tianjin Institute of Digestive Diseases, National Key Clinical Specialty, General Hospital, Tianjin Medical University, Tianjin, China.

Objectives: Currently, most colorectal neoplasia (CRN) screening strategies target asymptomatic individuals. However, studies on patients with non-specific gastrointestinal symptoms (NSGS) are limited. We aimed to develop a CRN risk score specifically for patients with NSGS.

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Background: Functional constipation (FCon) is a common functional gastrointestinal disorder (FGID). Studies have indicated a higher likelihood of psychiatric disorders, such as anxiety, depression, sleep disturbances, and impaired concentration, among patients with FCon. However, the underlying pathophysiological mechanisms responsible for these symptoms in FCon patients remain to be fully elucidated.

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