Expression and alternative splicing analysis of a large-conductance calcium-activated potassium channel gene in Plutella xylostella.

The large-conductance calcium-activated potassium channel (BK ) plays an important role in the regulation of insect neural circuits and locomotion, and thus is a potential target of insecticides. In this study, iberiotoxin, an inhibitor of BK , was found to prolong the anesthetic time of ethyl acetate on Plutella xylostella larvae. Therefore, the coding sequence of slowpoke gene coding the alpha subunit of BK was cloned to investigate the function of this channel in P.

ABCC2 participates in the resistance of Plutella xylostella to chemical insecticides.

The ABCC2 protein of Plutella xylostella is an important target of Cry1A toxins from Bacillus thuringiensis (Bt), but whether this protein is involved in the resistance of P. xylostella to other insecticides remains unclear. In this study, the abcc2 gene of P.