The Neuroplastic Outcomes from Impaired Sensory Expectations (NOISE) hypothesis: How ACL dysfunction impacts sensory perception and knee stability.

Background: The anterior cruciate ligament (ACL) is integral to maintaining knee joint stability but is susceptible to rupture during physical activity. Despite surgical restoration of passive or mechanical stability, patients struggle to regain strength and prior level of function. Recent efforts have focused on understanding how ACL-related changes in the nervous system contribute to deficits in sensorimotor control following injury and reconstruction.

A Rare Case Report of the Successful Management of Perforated Sigmoid Volvulus in a Pregnant Woman With Massive Pneumoperitoneum: First Case in Yemen.

Sigmoid volvulus during pregnancy is an extremely rare condition that presents as intestinal obstruction and can lead to severe complications for both the mother and fetus if not promptly diagnosed and treated. To our knowledge, this is the first documented case in Yemen. We report a case of a 39-year-old pregnant woman at 32 weeks of gestation who presented with acute abdominal pain, constipation, and signs of peritonitis.

Combinatorial treatment with traditional medicinal preparations and VEGFR-tyrosine kinase inhibitors for middle-advanced primary liver cancer: A systematic review and meta-analysis.

Background: This study aimed to investigate the therapeutic efficacy and safety of Traditional medicine preparations (TMPs) given in combination with vascular endothelial growth factor receptor (VEGFR)-associated multi-targeted tyrosine kinase inhibitors (TKIs) for the treatment of middle to advanced-stage primary liver cancer (PLC).

Methods: This systematic literature survey employed 10 electronic databases and 2 clinical trial registration platforms to identify relevant studies on the use of TMPs + VEGFR-TKIs to treat patients with middle-advanced PLC. Furthermore, a meta-analysis was performed following the PRISMA guidelines using the risk ratio (RR) at 95% confidence intervals (CI) or standardized mean difference as effect measures.

Harnessing insects mediated plastic biodegradation: Current insight and future directions.

Plastic polymers pose a significant challenge due to their resistance to degradation, resulting in their persistent accumulation in the environment and exacerbating a critical environmental concern. Urgent innovation and novel management technologies are essential to tackle this issue. Plastic biodegradation, distinguished by its environmentally friendly and safe attributes, has garnered substantial attention as a viable solution.

Examining the growing challenge: Prevalence of diabetes in young adults (Review).

Diabetes is rapidly spreading worldwide, affecting millions of individuals. Therefore, it is crucial to have a comprehensive understanding of its complications. The present review discusses the complex subject of diabetes, including the type 1 and type 2 variants.

Controllable and Facile Metallization of Polymer Surface with Biphasic Liquid Metals toward Soft Circuits.

Chemical metallization (e.g., chemical/electrical plating) of the polymer surface is an extremely important, convenient, cost-effective, and broadly applied strategy to realize combined advantages of functional metals and polymers for today's industry.

A bibliometric and visual analysis of Parkinson's disease sleep disorders: articles from 2008 to 2023.

Objective: Sleep disorder is a common non-motor symptom (NMS) of Parkinson's disease. However, the global research focus on Parkinson's sleep-related disorders (PDSDs) and future trends remains unclear. Currently, there is no bibliometric analysis of PDSDs.

Quercetin inhibits ferroptosis through the SIRT1/Nrf2/HO-1 signaling pathway and alleviates asthma disease.

Background: Quercetin (QCT) is a bioflavonoid derived from vegetables and fruits that has anti-inflammatory and anti-ferroptosis effects against various diseases. Previous studies have shown that QCT modulates the production of cellular inflammatory factors in asthma models and delays the development of chronic airway inflammation. However, the regulatory mechanism of QCT, a traditional Chinese medicine, in the treatment of asthma has not been elucidated.

A Rapid Method for Obtaining the Transgenic Roots of Crassulaceae Plants.

Crassulaceae plants are valued for their horticultural, ecological, and economic significance, but their genetic improvement is hindered by the absence of efficient and stable genetic transformation methods. Therefore, the development of a tailored genetic transformation method is crucial for enhancing the progress of the genetic improvement of Crassulaceae plants. The results indicate that, in the transformation experiments conducted on , the K599 strain exhibited the highest transformation efficiency (76.

Screening for Developmental Delays in Pediatric Cochlea Implant Candidates and Recipients.

Objective: Conduct a pilot clinical improvement project to effectively screen children with hearing loss for developmental delays. Children with hearing loss and cochlear implants (CIs) are at risk for additional developmental delays; however, screening to aid in early identification and referral for developmental delays is not routinely performed at CI centers. It is important to consider all aspects of child development to maximize CI outcomes and access to language.

A Review on Architecting Rationally Designed Metal-Organic Frameworks for the Next-Generation Li-S Batteries.

The modern era demands the development of energy storage devices with high energy density and power density. There is no doubt that lithium‒sulfur batteries (Li‒S) claim high theoretical energy density and have attracted great attention from researchers, but fundamental exploration and practical applications cannot converge to utilize their maximum potential. The design parameters of Li-S batteries involve various complex mechanisms, and their obliviousness has resulted in failure at the commercial level.

"Amr Sign": A Case-Control Study Evaluating the Diagnostic Value of a New Clinical Sign in the Diagnosis of Acute Appendicitis.

Introduction Acute appendicitis, a prevalent cause of acute abdominal pain and a common indication for emergency surgery, presents a diagnostic challenge due to its diverse clinical presentation and variability in appendix location and symptoms. Traditional diagnostic approaches, including physical examination, clinical scoring systems, and imaging techniques, have limitations. This study introduces the "Amr sign," a new diagnostic indicator characterized by sudden reflex hyperextension of the neck upon palpation of the right iliac fossa, which is hypothesized to reflect local peritoneal irritation from an inflamed appendix.

Research on Real-Time Roundup and Dynamic Allocation Methods for Multi-Dynamic Target Unmanned Aerial Vehicles.

When multi-dynamic target UAVs escape, the uncertainty of the formation method and the external environment causes difficulties in rounding them up, so suitable solutions are needed to improve the roundup success rate. However, traditional methods can generally only enable the encirclement of a single target, and when the target is scattered and escaping, this will lead to encirclement failure due to the inability to sufficiently allocate UAVs for encirclement. Therefore, in this paper, a real-time roundup and dynamic allocation algorithm for multiple dynamic targets is proposed.

Informing Psychosocial Care for Young Couples Coping with Early-Onset Breast Cancer: A Cross-Sectional Examination of Unmet Service Needs and Their Association with Psychological Distress in the First Year Post-Diagnosis.

Young women diagnosed with breast cancer report greater psychological and physical morbidity than both older women and healthy peers. Similarly, young partners experience elevated cancer-related distress. Psychosocial oncology programs are not frequently attuned to the needs of young adult patients and may exclude their social networks.

Metabolomic analysis reveals potential role of immunometabolism dysregulation in recurrent pregnancy loss.

Background: Recurrent pregnancy loss (RPL) affects women's reproductive health seriously, with immune dysfunction playing a key role in its cause, yet the exact mechanisms remain elusive. We aim to investigate potential mechanisms and identify biomarkers linked to RPL.

Methods: Immune cytokine testing and metabolomic profiling were conducted on the serum of 34 RPL patients and 30 healthy individuals.

Exploring reciprocal links between early adolescent coping and internalizing symptoms.

Introduction: The rising prevalence of depression and anxiety among adolescents is a public health concern. Early adolescence is a key developmental period to reduce risks for internalizing symptoms through primary prevention programs, yet additional research is needed on modifiable factors, such as coping skills, to target to mitigate risk factors. Therefore, we investigated the reciprocal link between coping style and internalizing symptoms among a racially/ethnically diverse sample of early adolescents (n = 1273) from 12 middle schools over 1 year.

One Health Index applied to countries in South America.

Introduction: The One Health concept has proposed an integrated and unified approach aiming for health balance and enhancement by recognizing the interdependence of human, animal, and environmental health. The COVID-19 pandemic has pushed global One Health initiatives and policy improvement toward preventive measures for future pandemics, particularly of zoonotic origin. Such a scenario may be particularly relevant for South America, which is considered highly vulnerable due to its natural biodiversity superposed to socioeconomic and environmental issues, demanding effective methods and indicators for proper One Health strategies and goals that are aligned with macroregional contexts.