Exploring optimal control strategies in a nonlinear fractional bi-susceptible model for Covid-19 dynamics using Atangana-Baleanu derivative.

In this article, a nonlinear fractional bi-susceptible [Formula: see text] model is developed to mathematically study the deadly Coronavirus disease (Covid-19), employing the Atangana-Baleanu derivative in Caputo sense (ABC). A more profound comprehension of the system's intricate dynamics using fractional-order derivative is explored as the primary focus of constructing this model. The fundamental properties such as positivity and boundedness, of an epidemic model have been proven, ensuring that the model accurately reflects the realistic behavior of disease spread within a population.

Transition symptom management careers: Historical patterns of mental health symptoms and service use among young adults experiencing a psychiatric crisis.

Young adults access mental health services at lower rates than both older and younger age groups despite high levels of need. Mental health service use is known to be influenced by prior experiences with treatment, with episodes of symptoms and treatment producing patterns of service use over time, or what we call a "symptom management career". This qualitative study examined the symptom management careers of 55 young adults (ages 18-25) who were admitted to an inpatient, short term, crisis stabilization unit.

Plasmonic colorimetric sensor based on alpha-cyclodextrin-functionalized silver nanoparticles for the selective detection of arsenic(iii) in aqueous media.

The optical detection of arsenic (As) in human biological fluids and environmental water samples is presented using alpha-cyclodextrin-modified silver nanoparticles (α/CyD-AgNPs) at the trace level. This method is based on the measurement of a red shift of the LSPR band of α/CyD-AgNPs in the region of 200-800 nm. The color of α/CyD-AgNPs was changed from yellow to colorless by the addition of As(iii).

Alterations in spontaneous brain activity of maintenance hemodialysis patients with restless legs syndrome: a cross-sectional case-control study.

Objective: Through resting state functional magnetic resonance imaging (rs-fMRI) we evaluate the spontaneous brain activity changes of maintenance hemodialysis (MHD) patients with restless legs syndrome (RSL) and analyzed the imaging features and related mechanisms of RLS in patients with MHD.

Method: We select 27 MHD patients with RLS and 27 patients without RSL matched by age, gender, cognitive function. Both groups underwent neuropsychological tests and MRI scans.

Double extreme-cum-median ranked set sampling.

Extreme-cum-median ranked set sampling has been developed to address the problem of heterogeneity and outliers / extreme values. Double ranked set sampling has been suggested to obtain more reliable samples using the concept of degree of distinguishability. Dealing with heterogeneous and non-normal populations seems to be an area with a dearth of research.

Fast, Highly Stable, and Low-Bandgap 2D Halide Perovskite Photodetectors Based on Short-Chained Fluorinated Piperidinium as a Spacer.

Ruddlesden-Popper (RP) two-dimensional (2D) halide perovskite (HP), with attractive structural and optoelectronic properties, has shown great potential in optoelectrical devices. However, the relatively wide bandgap () and stability, which cause inferior efficiency, prevent its feasibility from further applications. To tackle these issues, for the first time, a novel fluorine-containing piperidinium spacer, (3-HCFCFCHOCH-PPH), abbreviated as (4FH-PPH), has been designed for the stable and efficient = 1 2D HPs.

Microbiomic insights into the oral microbiome's role in type 2 diabetes mellitus: standardizing approaches for future advancements.

The burgeoning field of microbiomics has unveiled significant insights into the role of the oral microbiome in the pathophysiology of Type 2 Diabetes Mellitus (T2DM), with this review focusing on recent advancements in diabetic oral microbiology, its clinical applications, and identifying factors that may affect study interpretations. A comprehensive review across various databases, including PubMed and Google Scholar, was conducted to collate original research data published in the past five years, specifically targeting studies exploring the impact of the oral microbiome on T2DM and emphasizing research that employs microbiomic approaches in clinical patient populations. The findings delineate the intricate interplay between T2DM and oral microbiome dysbiosis, highlighting significant microbial shifts following periodontal and antidiabetic treatments, and pointing to the complexity of the relationship between oral health and systemic disease.

mA-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating Transcription.

Purpose: Hepatocellular carcinoma (HCC) is one of the most lethal malignancies in the world. Oncofetal proteins are the optimal diagnostic biomarkers and therapeutic targets for HCC. As the most abundant modification in RNA, N-methyladenosine (mA) has been reported to be involved in HCC initiation and progression.

Threat and Deprivation as Distinct Predictors of Posttraumatic Stress and Depression Symptoms in First and Second Generation Latinx Youth.

Recent adverse childhood experiences (ACEs) scholarship emphasizes that differing ACEs affect the onset and course of psychopathology, and that sociopolitical context contributes to ACEs experienced by marginalized youth. Guided by the Immigration-Related Adverse Childhood Experiences Model, we explored the associations between different ACEs-immigration enforcement fear and perceived economic hardship-on posttraumatic stress disorder (PTSD) and depression among first and second-generation Latinx youth in immigrant families. Participants (n=306) included students from 11 high schools in two states (58% female; 25% aged 17 or older).

Arsenite in plant biology: How plants tackle it?

Among toxic elements, arsenic (As) comes under group 1 carcinogenic metalloid. Its presence in the soil and irrigation water in a higher concentration than permissible limit has become a threat to crop production and human livelihood. Crop plants, specifically those used as staple foods, exhibit the highest As accumulation which subsequently accumulates in the human body after their consumption, leading to severe fatal diseases.

miR-142-3p Regulates Airway Inflammation Through PTEN/AKT in Children and Mice with Asthma.

Background: Asthma is the most common chronic pulmonary disease in children. MicroRNAs (miRNAs) play a regulatory role in the occurrence and development of asthma. We aimed to explore the differential expression of miRNAs in the peripheral blood of children with asthma and identify a miRNA that can alleviate asthma inflammation.

Understanding the toxicological effects of TiO nanoparticles extracted from sunscreens on human keratinocytes and skin explants.

Background: Inorganic ultraviolet filters such as titanium dioxide nanoparticles are frequently used in sunscreens. Numerous toxicological studies in vitro and in vivo have been conducted using pristine standard reference nanomaterials of these inorganic filters. While convenient, this approach is not realistic because the complex environment of sunscreen formulations could change the physicochemical properties of the nanoparticles and lead to vastly different toxicological outcomes.

Application of recombinase polymerase amplification with lateral flow assay to pathogen point-of-care diagnosis.

Since the outbreak of the new coronavirus, point-of-care diagnostics based on nucleic acid testing have become a requirement for the development of pathogen diagnostics, which require the ability to accurately, rapidly, and conveniently detect pathogens. Conventional nucleic acid amplification techniques no longer meet the requirements for pathogen detection in low-resource, low-skill environments because they require specialist equipment, complex operations, and long detection times. Therefore, recombinant polymerase amplification (RPA) is becoming an increasingly important method in today's nucleic acid detection technology because it can amplify nucleic acids in 20-30 minutes at a constant temperature, greatly reducing the dependence on specialist equipment and technicians.

Hydrogen Sulphide: A Key Player in Plant Development and Stress Resilience.

Based on the research conducted so far, hydrogen sulphide (HS) plays a crucial role in the development and stress resilience of plants. HS, which acts as a signalling molecule, responds to different stresses such as heavy metals, drought, and salinity, and it regulates various aspects of plant growth and development including seed germination, root development, stomatal movement, flowering, and fruit ripening. Additionally, HS is involved in mediating legume-Rhizobium symbiosis signalling.

National Study Examining Excellence and Value in Physical Therapist Residency Education: Part 1-Design, Methods, and Results.

Objective: A challenge in health professions is training practitioners to navigate health care complexities, promote health, optimize outcomes, and advance their field. Physical therapist residency education offers a pathway to meet these needs in ways that "entry-level" (professional) education may not. Identifying key aspects of excellence in residency education and understanding its value in developing adaptive expertise will help devise strategies to enhance program, resident, and patient outcomes.

National Study Examining Excellence and Value in Physical Therapist Residency Education: Part 2-A Call to Action.

This Perspective provides a crucial set of actions with corresponding recommendations aimed at propelling the physical therapy profession toward excellence in residency education. The conceptual model includes elements of excellence in the delivery and outcomes of physical therapist residency education and the domain of value experienced by stakeholders impacted by physical therapist residency education. Linked to the conceptual model, the 15 actions, and 28 recommendations draw from (1) the Physical Therapist Residency Excellence and Value (PT-REV) study, (2) the Physical Therapist Education for the 21st Century (PTE-21) study, and (3) research in the learning sciences.

Implementing Lifestyle Medicine Competencies in Didactic and Clinical Settings for Allied Health Professionals: A Call to Action.

In this article, we discuss and reflect on the essential components of our concurrent session presentation at the American College of Lifestyle Medicine (ACLM) annual conference LM2023, "Implementing Lifestyle Medicine Competencies in Didactic and Clinical Settings for Allied Health Professionals." We illustrate the necessity of interdisciplinary lifestyle medicine approaches through a conscious fusion of analysis and storytelling. This review concludes with a call to action empowering the medical community to embrace interdisciplinary lifestyle medicine approaches in effort to increase access to equitable healthcare.

Efficacy of B - mode and elastography ultrasound technique in the prediction of Helicobacter pylori: a prospective study.

Background: Helicobacter pylori (HP) affect nearly 50% of the world's population and can colonize the submucosal and mucosal layers of the stomach wall, causing inflammation leading to a thickening of these layers. The study aimed to evaluate the application value of transabdominal ultrasonography combined with elastography in the prediction of HP using HP Fecal Antigen Test as gold standard.

Method: This prospective case-control study was conducted in 174 participants classified into three groups: Group A: Symptomatic patients with thickened stomach antral and evident HP infection on fecal antigen test results, Group B: Symptomatic patients with thickened antral and no evident HP infection on fecal antigen test results, and Group C: control group of asymptomatic individuals with negative HP screening to predict the diagnostic accuracy of B-mode ultrasound and elastography in the prediction of HP pylori.

Not So Patient Friendly: Patient Education Materials in Rheumatology and Internal Medicine Fall Short of Nationally Recommended Readability Benchmarks in the United States.

Objective: Patient education materials (PEMs) can help promote health literacy (HL) among patients. However, their use depends on how easily patients can read and comprehend the information. Several national organizations recommend that text be written at a sixth- to eighth-grade level.

Exploring mitigation strategies for smog crisis in Lahore: a review for environmental health, and policy implications.

Smog, a combined form of atmospheric pollutants, dust, and smoke with fog under sunlight, poses a significant threat to human health and the environment by reducing visibility. Urban air pollution exposure can cause respiratory issues like asthma, pneumonia, chronic obstructive pulmonary disease (COPD), and cardiovascular diseases like heart attacks, high blood pressure, lung cancer, and other health issues like diabetes, cognitive decline, and even birth defects. As smog has become a growing global issue with severe impacts on public health, ecosystems, and economies, this study analyzes its effects and identifies appropriate policies for its mitigation.

Manual physical therapy for neck disorders: an umbrella review.

Introduction: Neck pain is a common musculoskeletal disorder, with a prevalence rate (age-standardized) of 27.0 per 1000 in 2019. Approximately 50-85% of individuals with acute neck pain do not experience complete resolution of symptoms, experiencing chronic pain.

(Q fever) exposure in wildlife professionals.

Introduction: Although occupational exposure to has been studied previously, the zoonotic risk in wildlife environments remains unclear and has yet to be fully established.

Methods: Accordingly, the present study aimed to serologically assess professionals with daily contact with free-living and captive wildlife in Paraná State, Brazil, along with the potential associated risk factors for exposure.

Results: Overall, 25 out of 309 (8.

Corneal Treatment, Repair, and Regeneration: Exosomes at Rescue.

Exosomes are extracellular vesicles within the nanosized range that play roles in intercellular communication and thus have certain biological activities. The secretory signaling communication mechanism is an efficient way of exchanging information between cells and has been investigated as nature's therapeutic drug carriers. This review will summarize the potential of exosomes as therapeutic tools and drug delivery vehicles for corneal pathologies.