1,703 results match your criteria: "Graduate Center of the City University of New York[Affiliation]"
Bioscience
December 2024
Department of Biology, City College of New York, City University of New York, New York, New York, United States.
Creating software tools that address the needs of a wide range of decision-makers requires the inclusion of differing perspectives throughout the development process. Software tools for biodiversity conservation often fall short in this regard, partly because broad decision-maker needs may exceed the toolkits of single research groups or even institutions. We show that participatory, collaborative codesign enhances the utility of software tools for better decision-making in biodiversity conservation planning, as demonstrated by our experiences developing a set of integrated tools in Colombia.
View Article and Find Full Text PDFACS Nano
December 2024
Department of Biomedical Engineering, The City College of New York, New York, New York 10031, United States.
Semiconducting single-walled carbon nanotubes (SWCNTs) may serve as signal transducers for nanobiosensors. Recent studies have developed innovative methods of engineering molecularly specific sensors, while others have devised methods of deploying such sensors within live animals and plants. These advances may potentiate the use of implantable, noninvasive biosensors for continuous drug, disease, and contaminant monitoring based on the optical properties of single-walled carbon nanotubes (SWCNTs).
View Article and Find Full Text PDFJ Phys Chem C Nanomater Interfaces
December 2024
Department of Chemistry, College of Staten Island, Staten Island, New York 10314, United States.
Density functional theory calculations and a finite deformation method are used to calculate second- and, most notably, third-order elastic constants of amorphous silicon and amorphous silicon dioxide, as represented by model structures generated via melt-quench force-field molecular dynamics simulations. Linear and nonlinear elastic constants are used to deduce macroscopic elastic moduli, such as the bulk and shear moduli, their pressure derivatives, and the elastic Grüneisen parameter. Our calculations show that the elastic properties of amorphous silicon reach the isotropic elastic limit within the nanometer length scale, attaining characteristics, both linear and nonlinear, comparable to those of crystalline silicon.
View Article and Find Full Text PDFBiochim Biophys Acta Gen Subj
December 2024
Department of Chemistry, York College of the City University of New York, Jamaica, New York 11451, USA; PhD Programs in Chemistry and Biochemistry, Graduate Center of the City University of New York, New York 10016, USA. Electronic address:
Atherosclerosis, the major underlying cause of cardiovascular disease, is believed to arise from the accumulation of low-density lipoprotein (LDL) in the arterial subendothelial space, ultimately leading to plaque formation. It is proposed that the accumulation of LDL is linked to its intrinsic aggregation propensity. Although the native LDL is not prone to aggregation, LDL(-), an electronegative LDL characterized in the plasma, has been shown to prime LDL aggregation in a domino-like behavior similar to amyloidogenic proteins.
View Article and Find Full Text PDFJ Chem Phys
December 2024
Department of Physics, Brooklyn College of the City University of New York, Brooklyn, New York 11210, USA.
We perform classical molecular dynamics (MD) and path-integral MD (PIMD) simulations of H2O and D2O using the q-TIP4P/F model over a wide range of temperatures and pressures to study the nuclear quantum effects (NQEs) on (i) the vitrification of liquid water upon isobaric cooling at different pressures and (ii) pressure-induced transformations at constant temperature between low-density amorphous and high-density amorphous ice (LDA and HDA) and hexagonal ice Ih and HDA. Upon isobaric cooling, classical and quantum H2O and D2O vitrify into a continuum of intermediate amorphous ices (IA), with densities in-between those of LDA and HDA (depending on pressure). Importantly, the density of the IA varies considerably if NQEs are included (similar conclusions hold for ice Ih at all pressures studied).
View Article and Find Full Text PDFJ Soc Pers Relat
September 2024
Department of Psychology, Hunter College of the City University of New York, USA.
Few studies have examined developmentally relevant sources of resilience, such as peer social support, among young sexual minority men (SMM) of color experiencing discrimination and mental health distress. To address this gap in the literature, we examined the role of peer social support in the association between discrimination and mental health distress in a sample of young SMM of color. Ninety-four cisgender young SMM of color (aged 16-29) were recruited through community-based organizations in the New York City metropolitan area as part of an effectiveness trial of a tailored Motivational Interviewing intervention.
View Article and Find Full Text PDFJ Environ Qual
December 2024
Department of Geography and Environmental Systems, University of Maryland, Baltimore County, Baltimore, Maryland, USA.
Hydrologic alterations associated with urbanization can weaken connections between riparian zones, streams, and uplands, leading to negative effects on the ability of riparian zones to intercept pollutants carried by surface water runoff and groundwater flow such as nitrate (NO ) and phosphate (PO ). We analyzed the monthly water table as an indicator of riparian connectivity, along with groundwater NO and PO concentrations, at four riparian sites within and near the Gwynns Falls Watershed in Baltimore, MD, from 1998 to 2018. The sites included one forested reference site (Oregon Ridge), two suburban riparian sites (Glyndon and Gwynnbrook), and one urban riparian site (Cahill) with at least two locations and four monitoring wells, located 5Â m from the center of the stream, at each site.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Physics, Queens College of the City University of New York, Flushing, New York, 11367, USA.
The quantum conductance and its classical wave analogue, the transmittance, are given by the sum of the eigenvalues of the transmission matrix. However, neither measurements nor theoretical analysis of the transmission eigenchannels have been carried out to explain the dips in conductance found in simulations as new channels are introduced. Here, we measure the microwave transmission matrices of random waveguides and find the spectra of all transmission eigenvalues, even at dips in the lowest transmission eigenchannel that are orders of magnitude below the noise in the transmission matrix.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Physics, AlbaNova University Center, Stockholm University, SE-10691, Stockholm, Sweden.
Recent experiments and theoretical studies strongly indicate that water exhibits a liquid-liquid phase transition (LLPT) in the supercooled domain. An open question is how the LLPT of water can affect the properties of aqueous solutions. Here, we study the structural and thermodynamic properties of supercooled glycerol-water microdroplets at dilute conditions (χ = 3.
View Article and Find Full Text PDFJ Acquir Immune Defic Syndr
December 2024
Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Implementation science has been heralded as a critical strategy for ending the HIV epidemic (EHE), and the United States (US) has made a tremendous financial investment in implementation research. However, several dynamics in its development and organization may alienate front-line implementers and recapitulate some of the same missteps that have stymied past translational work.
Setting: Increasing the accessibility and relevance of HIV implementation science for front-line implementers (e.
Commun Chem
December 2024
Department of Physics, Brooklyn College of the City University of New York, Brooklyn, NY, 11210, USA.
The potential energy landscape (PEL) formalism is a powerful tool within statistical mechanics to study the thermodynamic properties of classical low-temperature liquids and glasses. Recently, the PEL formalism has been extended to liquids/glasses that obey quantum mechanics, but applications have been limited to atomistic model liquids. In this work, we extend the PEL formalism to liquid/glassy water using path-integral molecular dynamics (PIMD) simulations, where nuclear quantum effects (NQE) are included.
View Article and Find Full Text PDFAppl Plant Sci
September 2024
Systematic and Evolutionary Botany Laboratory, Department of Biology Ghent University Ghent Belgium.
Premise: Hybridization capture kits are now commonly used for reduced representation approaches in genomic sequencing, with both universal and clade-specific kits available. Here, we present a probe kit targeting 799 low-copy genes for the plant family Annonaceae.
Methods: This new version of the kit combines the original 469 genes from the previous Annonaceae kit with 334 genes from the universal Angiosperms353 kit.
J Acquir Immune Defic Syndr
December 2024
Aaron Diamond AIDS Research Center (ADARC), Columbia University, New York, NY USA.
Background: Effective implementation of evidence-based HIV prevention interventions continues to be a challenge in the United States, and the field is increasingly turning to implementation science for solutions. As such, it is critical to expand the current implementation science vocabulary - and its taxonomy of implementation strategies - to increase its relevance and utility for front-line implementers.
Setting: Community-based health centers providing HIV prevention services in the Southeastern US.
Pharmacol Biochem Behav
December 2024
Department of Psychological and Brain Sciences, Colgate University, Hamilton, NY, USA. Electronic address:
ACS Chem Neurosci
December 2024
PhD Programs in Chemistry and Biochemistry, the Graduate Center of the City University of New York, New York, New York 10016, United States.
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the onset of COVID-19 have been linked to an increased risk of developing type 2 diabetes. While a variety of mechanisms may ultimately be responsible for the onset of type 2 diabetes under these circumstances, one mechanism that has been postulated involves the increased aggregation of human islet amyloid polypeptide (hIAPP) through direct interaction with SARS-CoV-2 viral proteins. Previous computational studies investigating this possibility revealed that a nine-residue peptide fragment known as SK9 (SFYVYSRVK) from the SARS-CoV-2 envelope protein can stabilize the native conformation of hIAPP by interacting with the N-terminal region of amylin.
View Article and Find Full Text PDFNeurosci Lett
January 2025
Department of Psychological and Brain Sciences, Colgate University, Hamilton, NY, USA. Electronic address:
Prolonged periods of opioid use have been shown to cause neuroadaptations in the brain's reward circuitry, contributing to addictive behaviors and drug dependence. Recently, considerable focus has been placed on the role of the endocannabinoid system (ECS) and its CB receptors in opioid-driven behaviors. However, opioid-induced neuroadaptations to the ECS remain understudied.
View Article and Find Full Text PDFPLoS One
November 2024
Department of Life Sciences, Long Island University Post, Brookville, NY, United States of America.
The COVID-19 pandemic highlighted the role of indoor environments on disease transmission. However, our understanding of how transmission occurred evolved as the pandemic progressed. Enclosed spaces where pathogen-laden aerosols accumulate were strongly linked to increased transmission events.
View Article and Find Full Text PDFbioRxiv
November 2024
Department of Chemistry, College of Staten Island, City University of New York, 2800 Victory Blvd., 6S-238, Staten Island, NY 10314.
This study investigates nucleosome dynamics using both all-atom and coarse-grained (CG) molecular dynamics simulations, focusing on the SIRAH force field. Simulations are performed for two nucleosomal DNA sequences-ASP and Widom-601-over six microseconds at physiological salt concentrations. Comparative analysis of structural parameters, such as groove widths and base pair geometries, reveals good agreement between atomistic and CG models, though CG simulations exhibit broader conformational sampling and greater breathing motion of DNA ends.
View Article and Find Full Text PDFJ Cancer Surviv
November 2024
Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Purpose: Cancer and cancer treatment have been associated with cognitive changes in survivorship, with forgetfulness and distractibility reported years post-treatment. Deficits in attention control may explain these difficulties. We assessed breast cancer survivors using a primary measure of attention control, the saccade/antisaccade task, to assess the effects of diagnosis and treatment.
View Article and Find Full Text PDFJ Org Chem
November 2024
Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.
Proc Natl Acad Sci U S A
November 2024
Department of Molecular, Cellular, and Biomedical Sciences, Center for Discovery and Innovation, City University of New York School of Medicine, New York, NY 10031.
Prev Med Rep
December 2024
Whitman-Walker Institute, District of Columbia, United States.
Objectives: This study examined research-related privacy and confidentiality concerns among adolescent sexual minority males (ASMM) and provides lessons learned to inform recruitment and enrollment strategies for this population.
Methods: Participants were a 2017-2018 internet-based U.S.
J Org Chem
December 2024
Department of Chemistry, Brooklyn College, The City University of New York, Brooklyn, New York 11210, United States.
α-Methoxytropone is a structural motif found in various natural products and other compounds of interest to the scientific community but remains a synthetic challenge. The present Note describes the synthesis of variously substituted α-methoxytropones and related compounds through an intermolecular 3-hydroxy-4-pyrone-based oxidopyrylium (5 + 2) cycloaddition followed by a samarium iodide-mediated reductive ring-opening. The strategy is highlighted in the synthesis of a novel AC-ring analogue of colchicine to compare it to existing methods.
View Article and Find Full Text PDFGlia
February 2025
Neuroscience Initiative, Advanced Science Research Center, CUNY, New York, New York, USA.
Ceramide C16 is a sphingolipid detected at high levels in several neurodegenerative disorders, including multiple sclerosis (MS). It can be generated de novo or from the hydrolysis of other sphingolipids, such as sphingomyelin or through the recycling of sphingosine, in what is known as the salvage pathway. While the myelin damage occurring in MS suggests the importance of the hydrolytic and salvage pathways, the growing interest on the importance of diet in demyelinating disorders, prompted us to investigate the involvement of de novo ceramide C16 synthesis on disease severity.
View Article and Find Full Text PDFJ Phys Chem B
November 2024
Department of Chemistry and Biochemistry, Brooklyn College of the City University of New York, New York, New York 11210, United States.
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ligand's binding selectivity free energy (BSFE) for the two receptors, which is the difference between the two individual binding free energies. In the receptor swapping protocol, the first ligand of a pair is transferred from one receptor to another while the second ligand is simultaneously transferred in the opposite direction.
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