1,881 results match your criteria: "Goztepe Training & Research Hospital[Affiliation]"

Comparative Analysis of Cosmetic and Functional Outcomes in Corneal Tattooing (Keratopigmentation) versus Ocular Prosthesis.

Eye Contact Lens

December 2024

Department of Ophthalmology (E.D., Z.B.S., E.E.E.O., H.O.), Istanbul Medeniyet University Goztepe Prof. Dr. Suleyman Yalçin City Hospital, Istanbul, Turkey; Goztepe Prof. Dr. Suleyman Yalçin City Hospital (O.F.Y.), Department of Ophthalmology, Istanbul, Turkey; and Haydarpasa Numune Education and Research Hospital (M.S.M.), University of Health Sciences, Sadik Eratik Eye Institute, Istanbul, Turkey.

Objectives: This study compares the cosmetic and functional outcomes of corneal tattooing/keratopigmentation and ocular prostheses in rehabilitating disfigured eyes, focusing on esthetic appearance and emotional well-being.

Methods: Ninety-two patients were included: 48 received corneal tattooing, and 44 were fitted with ocular prostheses. Anophthalmic surgery was indicated for trauma, painful blind eye, endophthalmitis, tumor, and corneal ulcer, while corneal tattooing was performed for trauma, corneal ulcer, and endophthalmitis.

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Objective: This study aims to evaluate the impact of preoperative stenting on surgical outcomes and complications in patients with bilateral ureteric stones, specifically assessing its role in reducing the need for subsequent interventions.

Methods: A retrospective analysis was conducted at a tertiary center over eight years, involving 82 patients with bilateral ureteric stones. Patients were divided into two groups: Group 1 (no preoperative stenting) and Group 2 (preoperative stenting).

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Objective: Spasticity developing in the upper extremity in stroke patients causes disability by limiting movement and causing pain. This study investigates the effects of botulinum toxin injections on pain, functionality, spasticity, and range of motion in hemiplegic patients with post-stroke spasticity.

Materials And Methods: The study involved a double-blind, prospective, randomized controlled trial with thirty-one stroke patients aged 35-80 who developed upper extremity spasticity.

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CHILDHOOD MENTAL TRAUMAS AND THE MEANING OF LIFE: THE MEDIATING ROLE OF FORGIVENESS.

Psychiatr Danub

December 2024

Department of Child and Adolescent Psychiatry, Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul, Turkey.

Childhood trauma can disrupt one's sense of the meaning of life. Forgiveness can be an important strategy in restoring the meaning of life and gaining a new meaning. In this context, the present study aims to test the theoretical model evaluating the hypothesis that forgiveness repairs the meaning of life deteriorated after traumas and makes positive contributions.

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Extremely elevated erythrocyte sedimentation rates: Associations with patients' diagnoses and clinical characteristics.

Rom J Intern Med

December 2024

Department of Internal Medicine Goztepe Training and Research Hospital, Istanbul Medeniyet University, Kadikoy/Istanbul, Türkiye.

Introduction: The aim of the study was to assess the etiological distribution of patients with an erythrocyte sedimentation rate (ESR) over 100 mm/hour and to evaluate differences in demographic, comorbidity, laboratory characteristics, and clinical outcomes.

Methods: This retrospective observational clinical study included patients aged 18 years and older who were admitted to the internal medicine inpatient clinic between May 1, 2015 and June 1, 2021 and had ESR values above 100 mm/h. Demographic data, comorbidities, laboratory parameters, imaging studies, histopathological findings, microbiological and serological data, along with in-hospital and post-discharge mortality, were collected from the hospital's electronic database.

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Objectives: To examine citrate anticoagulation in continuous renal replacement therapy (CRRT) in the PICU.

Design: Post hoc analysis of a curated, multicenter dataset collected from January 1, 2022, to June 1, 2023.

Setting: Seven PICUs in Turkey.

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Article Synopsis
  • - The study focuses on improving transitional care for adolescents with juvenile idiopathic arthritis (JIA) as they move to adult healthcare systems, suggesting the need for tailored programs in each country.
  • - A Delphi study involving adolescents, parents, and clinicians was conducted to gather expert opinions and identify key components of transitional care, with significant participation in the initial surveys.
  • - While a consensus was reached on essential transitional care issues for JIA patients, further agreement is needed on practical applications of a final checklist to enhance care in Turkey.
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Objectives: To evaluate the effectiveness of intramedullary nailing combining with iliac or fibular autograft for the treatment of adult forearm nonunions.

Methods: Design: Retrospective case series.

Setting: Two academic trauma referral center.

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Objective: Macroprolactinemia is a well-described endocrine disorder, with its results leading to unnecessary tests and overtreatment. However, routine macroprolactin screening is not performed in many laboratories. Routinely used prolactin assays can result in false diagnosis of hyperprolactinemia in patients with no signs and symptoms related to hyperprolactinemia and clinicians should be aware of macroprolactinemia frequency encountered with the method in use.

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Background: Medial tibial stress syndrome (MTSS) is a common leg injury in military personnel and athletes and is especially related to running and jumping. A patient-reported outcome measure, the MTSS score, was developed to determine the severity of MTSS.

Purpose: To translate, culturally adapt, and validate the MTSS score for the Turkish language.

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Background: This study aims to identify factors predicting recurrence and unfavorable prognosis in cN+ patients who have undergone sentinel lymph node biopsy (SLNB) following neoadjuvant chemotherapy (NAC).

Methods: The retrospective multi-centre "MF18-02" and the prospective multi-centre cohort registry trial "MF18-03" (NCT04250129) included patients with cT1-4N1-3M0 with SLNB+/- axillary lymph node dissection (ALND) post-NAC.

Results: A total of 2407 cN+ patients, who later achieved cN0 status after NAC and subsequently underwent SLNB, were studied.

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Our study is aimed at examining the Ice Hockey National Team players with regard to ACE I/D (rs1799752), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms and physical tests. This study was participated by 21 players from ice hockey national team. While ACE I/D (rs1799752) polymorphism was obtained using conventional polymerase chain reaction method (PCR), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms were produced by real time polymerase chain reaction method (qPCR).

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Article Synopsis
  • * The study involved 38 TM patients and 25 healthy controls, revealing that SWE parameters were significantly higher in TM patients compared to healthy controls, indicating more advanced liver condition.
  • * Although no significant differences in SWE were found among TM patients with varying levels of iron overload, the study suggests that SWE could serve as a valuable tool for early liver damage detection, paving the way for further research.
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The journey of MEFV heterozygous children: with or without colchicine.

Eur J Pediatr

November 2024

Department of Pediatric Rheumatology, Faculty of Medicine, Istanbul University, İstanbul, Türkiye.

To investigate the rate of colchicine use in the longitudinal follow-up of familial Mediterranean fever (FMF) carriers and identify variables that could predict the necessity of colchicine treatment in this group. The study was conducted in 9 pediatric rheumatology centers. The files of children with MEFV gene carriers were retrospectively reviewed between February 2014 and May 2024.

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Obesity as a risk factor for neuropathy: a case-control study.

Hormones (Athens)

November 2024

Department of Family Medicine, Faculty of Medicine, Health Sciences University, Istanbul, Turkey.

Aim: Neuropathy, a common complication of diabetes associated with metabolic issues, lacks clarity regarding its prevalence in metabolically healthy obese versus non-obese individuals. Our study aims to compare neuropathy rates between those with and those without obesity and who are metabolically healthy.

Methods: We included individuals aged 20-50, one group with a body mass index (BMI) ≥ 30 kg/m² (metabolically healthy and obese) and another with a BMI < 30 kg/m² (metabolically healthy and non-obese).

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The clinical relevance of cut-off percentage for high-grade urothelial carcinoma within low-grade urothelial carcinoma: A determining factor?

Urol Oncol

November 2024

Urology Department, Istanbul Medeniyet University Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkey; Dr. Erkin caddesi, Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi Üroloji birimi, Kadıköy-Istanbul, Turkey.

Aims: The aim of the study was to analyze the cut-off value for the percentage of the high-grade (HG) component that has clinical significance in urothelial carcinoma (UC).

Material And Methods: The study included a total of 362 patients, mixed-grade UC (MGUC) patients were classified as Combine Group (CG) 1 based on the presence of less than 5% HG areas. High-grade papillary UC (HGPUC) patients were grouped based on HG component proportions: CG2 (≥5%-<50% HG), CG3 (≥50%-<100% HG), and pure HGPUC (PHGPUC) for 100% HG components.

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Article Synopsis
  • The study focused on children with symptomatic omphalomesenteric duct (OMD) anomalies, analyzing 35 cases from a hospital over four years.
  • Most patients were male (82.8%) with symptoms primarily related to gastrointestinal tract obstruction, acute abdomen, or umbilical issues.
  • Surgical interventions varied, with successful outcomes and only two complications, showcasing the effectiveness of surgical treatment for these anomalies.
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Data in the literature on the use of ceftazidime-avibactam (CAZ-AVI) in carbapenem-resistant Klebsiella pneumoniae bloodstream infections (CRKP-BSIs) are limited especially in OXA-48 (Oxacillinase-48) predominant regions. Our study aimed to evaluate the effect of CAZ-AVI use on outcomes in CRKP-BSIs in Turkey, where OXA-48 is endemic. A multicenter retrospective observational study was conducted between January 2017 and September 2021.

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Article Synopsis
  • * It found that the RSV only group had lower pH and higher rates of bronchiolitis, while the RSV with viral agents group experienced longer hospital stays and more severe symptoms.
  • * Additionally, cases with bacterial co-infections were generally younger and had different clinical markers, highlighting that combined viral and bacterial infections can worsen RSV severity and impact treatment approaches like High Flow Nasal Cannula-Oxygen Therapy.
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Patients with crush syndrome and kidney disease: lessons learned from the earthquake in Kahramanmaraş, Türkiye.

Kidney Int

November 2024

Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Istanbul University, Istanbul, Türkiye.

Article Synopsis
  • * About 9.8% of the patients died during hospitalization, with older individuals and those with preexisting kidney issues showing higher mortality rates due to severe injuries and complications.
  • * Key factors influencing mortality included age, injury severity, shock, and certain elevated lab values, highlighting the need for better disaster preparedness and health care improvements for future events.
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Background: The objective of this study was to assess the accuracy of VO measurements in predicting long-term major adverse cardiac events (MACEs) in patients with high cardiovascular risk.

Methods: Based on a 10-year atherosclerotic cardiovascular disease risk score, 333 patients with high cardiovascular risk were included in this retrospective analysis. The study endpoint was MACEs, comprising all-cause mortality, cardiovascular mortality, non-fatal myocardial infarction or stroke, and coronary revascularization.

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Background: Ralstonia pickettii is an aerobic Gram-negative non-fermentative bacillus. It is an opportunistic pathogen that has recently prompted nosocomial outbreaks. Although it has low virulence, it can cause a wide range of invasive diseases in immunosuppressive patients.

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Article Synopsis
  • * A case study details a 72-year-old woman who developed a pseudoaneurysm in her SGA three weeks after surgery, which manifested as a hematoma and was successfully treated with embolization.
  • * Early detection and management of SGA injuries are crucial, with methods like CT angiography aiding diagnosis, and surgeons should exercise caution during procedures to avoid increasing the chance of such injuries.
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Article Synopsis
  • Abdominal actinomycosis is a rare infection, often misdiagnosed, caused by bacteria normally found in the oral cavity and gut, which can lead to conditions that mimic serious abdominal issues, including cancers.
  • A case study of a 59-year-old male with existing health problems showed how he was initially misdiagnosed with appendicitis but was later found to have actinomycosis during surgery.
  • The patient received successful treatment through surgery and penicillin, illustrating the need for healthcare providers to consider abdominal actinomycosis when diagnosing abdominal pain and masses.
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Intravascular lobular capillary hemangioma (ILCH), also known as intravenous pyogenic granuloma, is a benign vascular lesion with a distinctive lobular arrangement of capillaries. It is typically confined to the head, neck, and upper extremities, and its occurrence in the testicular region is exceedingly rare. Here, we present a case of a 68-year-old male who was initially diagnosed with a testicular tumor based on imaging studies but was later found to have an ILCH located in the epididymis.

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