Comparative analysis of gut bacteria of silkworm Bombyx mori L. on exposure to temperature through 16S rRNA high throughput metagenomic sequencing.

Global warming is one of the serious threats that adversely affects the development and reproduction of silkworms. The ideal temperature for silkworms to carryout normal life activities is 20-30 °C. Certain bivoltine silkworms that are raised in tropical regions are thermotolerant.

What can we learn from previous pandemics to reduce the frequency of emerging infectious diseases like COVID-19?

The global risks report of 2020 stated, climate-related issues dominate all of the top-five long-term critical global risks burning the planet and according to the report, "as existing health risks resurge and new ones emerge, humanity's past successes in overcoming health challenges are no guarantee of future results." Over the last few decades, the world has experienced several pandemic outbreaks of various pathogens and the frequency of the emergence of novel strains of infectious organisms has increased in recent decades. As per expert opinion, rapidly mutating viruses, emergence and re-emergence of epidemics with increasing frequencies, climate-sensitive vector-borne diseases are likely to be increasing over the years and the trends will continue and intensify.

Sonerila nairii (Melastomataceae) - a new species from the southern Western Ghats, India.

The new species Sonerila nairii (Melastomataceae) is here described from Pothumala of the Nelliampathy hill ranges of Western Ghats of Kerala, India. Morphologically it most closely resembles Sonerila erecta and Sonerila pulneyensis from which differs by the form of the stem, leaves, peduncle, pedicel, inflorescence, pubescence of the stem, leaves and hypanthium, and by the form of stamens and stigma.

A new fluorescent based screening system for high throughput screening of drugs targeting HBV-core and HBsAg interaction.

The existing screening systems for anti-hepatitis B virus (anti-HBV) drug discovery is time-consuming mainly due to the laborious detection system it is using. A new fluorescence based screening system for high throughput anti-HBV drug discovery was created by tagging hepatitis B surface antigen (HBsAg) with monomeric red fluorescent protein and hepatitis B virus (HBV) core protein with enhanced green fluorescent protein. The two constructs were co-transfected on to Hep3B cells and the transfection was stabilized by fluorescent activated cell sorter (FACS).

Anti-HBV activity of the different extracts from Phyllanthus rheedei Wight in cell culture based assay systems.

Ethnopharmacological Relevance: Phyllanthusrheedei Wight is a plant used by Muthuvan tribes of Kerala for treating liver related diseases.

Materials And Methods: The different extracts of Phyllanthus rheedei were analysed on cell lines were viz, PLC/PRF, Hep3B, FLCII10 and HepG2215 for its anti-HBV property. The analysis was done through ELISA, SQRT-PCR and immuno blotting.