Statistical Inference of the Half-Logistic Inverse Rayleigh Distribution.

The inverse Rayleigh distribution finds applications in many lifetime studies, but has not enough overall flexibility to model lifetime phenomena where moderately right-skewed or near symmetrical data are observed. This paper proposes a solution by introducing a new two-parameter extension of this distribution through the use of the half-logistic transformation. The first contribution is theoretical: we provide a comprehensive account of its mathematical properties, specifically stochastic ordering results, a general linear representation for the exponentiated probability density function, raw/inverted moments, incomplete moments, skewness, kurtosis, and entropy measures.

The Truncated Cauchy Power Family of Distributions with Inference and Applications.

As a matter of fact, the statistical literature lacks of general family of distributions based on the truncated Cauchy distribution. In this paper, such a family is proposed, called the truncated Cauchy power-G family. It stands out for the originality of the involved functions, its overall simplicity and its desirable properties for modelling purposes.

Energy trilemma based prioritization of waste-to-energy technologies: Implications for post-COVID-19 green economic recovery in Pakistan.

As lockdown eases, economic activities resume in Pakistan. If the country continues to follow business-as-usual (BAU) then it is anticipated that carbon output could surge past pre-COVID-19 levels - that means more disasters in future. Thus, it is an unprecedented opportunity to shift from BAU and achieve carbon-neutral and nature-positive economic recovery - green economic recovery (GER).

Association between meteorological indicators and COVID-19 pandemic in Pakistan.

This study was designed to investigate the impact of meteorological indicators (temperature, rainfall, and humidity) on total COVID-19 cases in Pakistan, its provinces, and administrative units from March 10, 2020, to August 25, 2020. The correlation analysis showed that COVID-19 cases and temperature showed a positive correlation. It implies that the increase in COVID-19 cases was reported due to an increase in the temperature in Pakistan, its provinces, and administrative units.

Protective and therapeutic effects of natural products against diabetes mellitus via regenerating pancreatic β-cells and restoring their dysfunction.

Diabetes mellitus is a growing public health concern and an increasing interest has been raised to search for new compounds with therapeutic effects on β-cells. There are chronic insulin resistance and loss of β-cell mass in the case of type-2 diabetes which covers about 90% of total diabetic patients. This work aims to critically review the protective and regenerative effects of various antidiabetic natural products on pancreatic β-cells.

Modeling smallholder livestock herders' intentions to adopt climate smart practices: An extended theory of planned behavior.

Climate change is persistently causing adverse effects to the agriculture sector of developing countries, specifically in Asia. Pakistan is no exception to this effect and is ranked among the top 10 countries, which are most vulnerable to climate change. A huge upcoming challenge is to sustain an equilibrium among production and environmental protection.

Biosafety and biosecurity approaches to restrain/contain and counter SARS-CoV-2/COVID-19 pandemic: a rapid-review.

Emergence and reemergence of infectious diseases pose significant public health risks that are continuously haunting human civilization in the past several decades. Such emerging pathogens should be considered as a high threat to humans, animals, and environmental health. The year 2020 was welcomed by another significant virus from family called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that caused the coronavirus disease 2019 (COVID-19).

Correction: Magnetic mesoporous bioactive glass for synergetic use in bone regeneration, hyperthermia treatment, and controlled drug delivery.

[This corrects the article DOI: 10.1039/C9RA09349D.].

Magnetic mesoporous bioactive glass for synergetic use in bone regeneration, hyperthermia treatment, and controlled drug delivery.

A combination of chemotherapy with hyperthermia can produce remarkable success in treating advanced cancers. For this purpose, magnetite (FeO)-doped mesoporous bioactive glass nanoparticles (FeO-MBG NPs) were synthesized by the sol-gel method. FeO-MBG NPs were found to possess spherical morphology with a size of approximately 50 ± 10 nm and a uniform pore size of 9 nm.

Oral delivery and enhanced efficacy of antimonal drug through macrophage-guided multifunctional nanocargoes against visceral Leishmaniasis.

The present study aimed on the site specific delivery and enhanced in-vivo efficacy of antimonial drugs against the visceral leishmaniasis via macrophage targeted mannose anchored thiomer based nanoparticles. Mannose anchored thiolated nanoformulation [M-(CS-g-PEI)-TGA] was developed and evaluated in terms particle size, zeta-potential and entrapment efficacy. The TEM and EDX analysis was carried out to evaluate the morphology and successful entrapment of antimonial drug.

The impact of temperature, rainfall, and health worker density index on road traffic fatalities in Pakistan.

A road traffic accident is a burning issue because the cost of road accidents is about 2% of gross domestic product in Pakistan. This paper explores the relationship between health force density index, temperature, rainfall, road lengths, and road traffic fatalities in Pakistan from 1985 to 2016. The stationarity was determined with the help of four-unit root tests.

Foliar micromorphology and its role in identification of the Apocynaceae taxa.

In the present study, we evaluate the importance of foliar epidermal micromorphological characteristics of Apocyanaceae for accurate identification and classification. The species were collected from the University of Peshawar's main campus in the spring season to observe its qualitative and quantitative features. The length and width of guard cells, stomatal pore and subsidiary cells, trichomes, and crypts on both sides of the leaf were examined.

Relationship between inward FDI and environmental degradation for Pakistan: an exploration of pollution haven hypothesis through ARDL approach.

In many developing countries, rising pollution and FDI inflows are positively correlated. This paper explores the existence of pollution haven hypothesis in Pakistan by employing the autoregressive distributed lag (ARDL) bounds test on yearly data from 1971 to 2014 for foreign direct investment inflow and four pollutants, i.e.

1,4-Diazepines: A Review on Synthesis, Reactions and Biological Significance.

Background: 1,4-Diazepines are two nitrogen containing seven membered heterocyclic compounds and associated with a wide range of biological activities. Due to its medicinal importance, scientists are actively involved in the synthesis, reactions and biological evaluation of 1,4-diazepines since number of decades.

Objective: The primary purpose of this review is to discuss the synthetic schemes and reactivity of 1,4- diazepines.

Assessment of biological activities of chitosan Schiff base tagged with medicinal plants.

A chitosan Schiff base with an aromatic aldehyde was synthesized and characterized by FTIR and NMR spectroscopies. Furthermore, the degree of substitution was calculated based on the ratios of the area of the proton of the imine (A ) and the area of the peak of the proton of the pyranose ring (A ). The antimicrobial activities were determined against bacterial and fungal strains, as well as multiple drug-resistant (MDR) bacteria.

A Molecular Approach on the Protective Effects of Mangiferin Against Diabetes and Diabetes-related Complications.

Background: Diabetes and its related complications are now a global health problem without an effective therapeutic approach. There are many herbal medicines which have attracted much attention as potential therapeutic agents in the prevention and treatment of diabetic complications due to their multiple targets.

Aim: The aim of this study is to review available knowledge of mangiferin focusing on its mode of action.

An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan.

Background: Skin diseases are a major health concern especially in association with human immune deficiency syndrome and acquired an immune deficiency. The aim of this study was to document the ethnomedicinal information of plants used to treat skin diseases in Northern Pakistan. This is the first quantitative ethnobotanical study of therapeutic herbs utilized by the indigenous people of Northern Pakistan for skin diseases.

: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses.

(Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments. The present work aimed to critically and extensively review its traditional uses, phytochemistry, pharmacology, toxicology, and taxonomy together with the mechanisms of action of selected extracts of .

Road traffic fatalities and its determinants in high-income countries: a continent-wise comparison.

Road traffic accidents (RTAs) are accountable for 1.2 million deaths and road safety is the part of sustainable development goals, which aims to provide a safe, accessible, affordable, and sustainable transport system by 2030. This study discovered the nexus of road traffic fatalities (RTFs) with its determinants in Asia, Europe, and America.

Status of Indian medicinal plants in the International Union for Conservation of Nature and the future of Ayurvedic drugs: Shouldn't think about Ayurvedic fundamentals?

The present market for herbal drugs is estimated about ₹40 billion, which is expected to increase by 16% in next 3-4 years. The current production of many Ayurvedic herbs is less than their market demand, which incentivizes adulteration in the Ayurvedic drug supply chain. The present work aims to highlight the most used Ayurvedic plants that have been listed in the International Union for Conservation of Nature's "red list" of endangered or vulnerable plants.

Ethnomedicinal Investigation of Medicinal Plants of Chakrata Region (Uttarakhand) Used in the Traditional Medicine for Diabetes by Jaunsari Tribe.

The Himalayan region is the treasure house of natural wealth, particularly of medicinal and aromatic plants. These plants are used by the Indian traditional healers for the past many centuries to treat various ailments such as skin disorders, asthma, diabetes, snake bite, fever, pain, eye diseases, diarrhoea, indigestion, jaundice, burn, wound, liver disorder, CNS disorders and urinary tract infection. The indigenous traditional knowledge of medicinal plants and therapies of various local communities has been lost due to changes in traditional culture and the introduction of modern technologies.

Investigative evaluation of for antibacterial capacity and biomimetic synthesis of silver nanoparticles.

is used for medicinal purposes for a long time all over the world. In this study, the authors report the antimicrobial potential of extracts obtained with different solvents. The extract(s) obtained with ethyl acetate yielded the best antibacterial effects because of a rich supply of oxalates and alkaloids in it.

Evaluation of cytotoxicity, hemocompatibility and spectral studies of chitosan assisted polyurethanes prepared with various diisocyanates.

In this research work cytocompatibility, mutagenicity, and hemolytic activity of chitosan-based polyurethanes (PUs) have been evaluated. The chitosan modified PUs were prepared by step-growth polymerization technique using various diisocyanates like isophorone diisocyanate (IPDI). 4,4'-methylenedicyclohexyl diisocyanate (HMDI), 2,4-toluene diisocyanate (TDI) and hexamethylene diisocyanate (HMDI) by reacting with hydroxyl-terminated polybutadiene (HTPB).

The dependency analysis between energy consumption, sanitation, forest area, financial development, and greenhouse gas: a continent-wise comparison of lower middle-income countries.

This study explored the long-run association among greenhouse gases (GHGs), financial development, forest area, improved sanitation, renewable energy, urbanization, and trade in 24 lower middle-income countries from Asia, Europe, Africa, and America (South and North) by using panel data from 1990 to 2015. Granger causality was tested by Toda and Yamamoto approach. The bi-directional causality was established among urbanization and GHGs (Asia), financial development and forest (Asia), energy use and renewable energy (Asia), renewable energy and forest (Asia), improved sanitation and forest (Asia, Africa, America), urbanization and forest (Asia), and improved sanitation and financial development (Europe).