123 results match your criteria: "Government Post graduate College[Affiliation]"

The wild edible plants offer a valuable resource for food and human nutrition. The current study aimed to analyze the proximate composition and ethno-medicinal profiles of twenty selected wild edible plants from the Malakand District, Pakistan. The proximate composition (moisture, ash, crude protein, crude fat, and dietary fiber) was analyzed following Association of Official Agricultural Chemists (AOAC) protocols.

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Systematic review on buparvaquone resistance associated with non-synonymous mutation in drug binding genes site of Theileria annulate.

Vet Parasitol

December 2024

State Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu 730046, China. Electronic address:

Theileria annulata (T. annulata) is intra-erythrocytic protozoan parasite which is more prevalent in tropical and sub-tropical countries. It has a significant economic impact on the productivity of the dairy industry, and buparvaquone is used to treat infected animals in the prevalent regions of the world.

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Article Synopsis
  • Bio-metabolites, including proteins and carbohydrates, are essential in the green synthesis of nanoparticles, making them safer and more effective than traditional methods.
  • These biomolecules serve as reducing agents that help convert metal ions into stable nanoparticles through various chemical mechanisms.
  • The engineered nanoparticles have promising applications across diverse fields such as medicine, agriculture, and electronics due to their unique properties.
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(Lam.) Oken, a multipurpose medicinal herb, has drawn much interest for its therapeutic qualities from both traditional and modern medicine systems. Many active secondary metabolites, such as bufadienolides, triterpenes, phenols, alkaloids, glycosides, lipids, flavonoids, and organic acids, are responsible for the plant's curative properties.

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A reduced pressure glow discharge is produced by passing a high-power pulsed DC source of 0-500 W with a frequency of 50 Hz across two parallel disk electrodes. A hydrogen peroxide aqueous solution is used as a flowing gas for discharge generation. Optical emission spectroscopy is employed to diagnose the discharge generated at a reduced pressure of 0.

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Antiviral Shrimp lncRNA06 Possesses Anti-Tumor Activity by Inducing Apoptosis of Human Gastric Cancer Stem Cells in a Cross-Species Manner.

Mar Drugs

May 2024

College of Life Sciences, Laboratory for Marine Biology and Biotechnology of Pilot National Laboratory for Marine Science and Technology (Qingdao), Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhejiang University, Hangzhou 310058, China.

Virus infection causes the metabolic disorder of host cells, whereas the metabolic disorder of cells is one of the major causes of tumorigenesis, suggesting that antiviral molecules might possess anti-tumor activities by regulating cell metabolism. As the key regulators of gene expression, long non-coding RNAs (lncRNAs) play vital roles in the regulation of cell metabolism. However, the influence of antiviral lncRNAs on tumorigenesis has not been explored.

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Dye solubilization in microemulsion based on Cetyltrimethylammonium bromide (CTAB) and its modified forms (counter-anions based upon Zn, Cu and Fe) is comparatively innovative and not explored in existing literature. Here, surfactant with modified counterions (SMCs) were used to study the effects of metal chlorides (ZnCl, CuCl and FeCl) modifications on the comparative solubilization of Rhodamine-B (RB) by Cetyltrimethylammonium bromide (CTAB) and its modified forms. The solubility of RB in different microemulsions were studied using UV-Visible spectroscopy and phase diagrams of CTAB with modified counter ions CTA[ZnCl.

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This paper addresses new exponential estimators for population mean in case of non-response on both the study and the concomitant variables using simple random sampling. The expressions for theoretical bias and mean square error of new estimators are derived up to first-order approximation and comparisons are made with the existing estimators. The proposed estimators are observed more efficient as compared to the considered estimators in the literature.

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Estimation of population mean is a determined subject issue in sampling surveys and many efforts have been paid by various researchers to enhance the precision of the estimates by utilizing the correlated auxiliary information. In connection with this, we suggest an improved exponential ratio-cum-ratio estimator using transformed auxiliary variables under ranked set sampling scheme. Theoretical comparison between estimators is made in terms of mean square errors (), percentage relative efficiencies (), and percentage relative root mean squared error ().

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Remediating inorganic pollutants is an important part of protecting coastal ecosystems, which are especially at risk from the effects of climate change. Different Phragmites karka (Retz) Trin. ex Steud ecotypes were gathered from a variety of environments, and their abilities to remove inorganic contaminants from coastal wetlands were assessed.

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3D-Printed Hydrogel for Diverse Applications: A Review.

Gels

December 2023

Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ 07102, USA.

Hydrogels have emerged as a versatile and promising class of materials in the field of 3D printing, offering unique properties suitable for various applications. This review delves into the intersection of hydrogels and 3D printing, exploring current research, technological advancements, and future directions. It starts with an overview of hydrogel basics, including composition and properties, and details various hydrogel materials used in 3D printing.

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The manufacturing sector is paying close attention to plastic matrix composites (PMCs) reinforced with natural fibres for improving their products. Due to the fact that PMC reinforced with naturally occurring fibres is more affordable and has superior mechanical qualities. Based on the application material requirements, An important step in the production of PMC is choosing the right natural fibres for reinforcing and determining how much of each.

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Alzheimer's disease (AD) is a neurological disease that disturbs the memory, thinking skills, and behavior of the affected person. AD is a complex disease caused by the breakdown of acetylcholine acetylcholinesterase (AChE). The present study aimed to assess the synthetic inhibitors of AChE that could be used to treat AD.

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Quality Standards and Pharmacological Interventions of Natural Oils: Current Scenario and Future Perspectives.

ACS Omega

October 2023

IIMT College of Medical Sciences, IIMT University, O Pocket, Ganga Nagar, Meerut, Uttar Pradesh 250001, India.

Medicinal plants are rich sources of natural oils such as essential and fixed oils used traditionally for nutritive as well as medicinal purposes. Most of the traditional formulations or phytopharmaceutical formulations contain oil as the main ingredient due to their own therapeutic applications and thus mitigating several pathogeneses such as fungal/bacterial/viral infection, gout, psoriasis, analgesic, antioxidant, skin infection, etc. Due to the lack of quality standards and progressive adulteration in the natural oils, their therapeutic efficacy is continuously deteriorated.

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The present investigation profoundly asserted the catalytic potential of plant-based aldo-ketoreductase, postulating its role in polyketide biosynthesis and providing new insights for tailored biosynthesis of vital plant polyketides for therapeutics. Plants hold great potential as a future source of innovative biocatalysts, expanding the possibilities within chemical reactions and generating a variety of benefits. The aldo-keto reductase (AKR) superfamily includes a huge collection of NAD(P)H-dependent oxidoreductases that carry out a variety of redox reactions essential for biosynthesis, detoxification, and intermediary metabolism.

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In this work, we have conducted an ab initio computational research of the pressure impact on the structural, elastic, thermodynamic, electronic, and optical properties of Be-based fluoroperovskite XBeF3 (X= K, Rb) compounds by using GGA+ PBEsol functional based on DFT in the CASTEP Package. These compounds' ground state characteristics were examined, including the lattice parameters, coefficient compressibility (B), and its pressure derivative(B'). Structural characterization shows that these compounds keep a cubic crystal structure with the impact of stress till 18 GPa.

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Tailored mesoporous γ-WO nanoplates: unraveling their potential for highly sensitive NH detection and efficient photocatalysis.

Phys Chem Chem Phys

November 2023

Advance Nanomaterial Research Laboratory, Department of Physics, University of Allahabad, Prayagraj, Uttar Pradesh, 211002, India.

Herein, the monoclinic phase of tungsten oxide (γ-WO) was successfully obtained after annealing hydrothermally synthesised WO powder at 500 °C. As per the result obtained from the N adsorption-desorption isotherm, the material has been identified as mesoporous with a specific surface area of 3.71 m g from BET (Brunauer-Emmett-Teller) analysis.

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The current research work was carried out to simulate monthly streamflow historical record using Soil and Water Assessment Tool (SWAT) and Artificial Neural Network (ANN) at the Astore Basin, Gilgit-Baltistan, Pakistan. The performance of SWAT and ANN models was assessed during calibration (1985-2005) and validation (2006-2010) periods via statistical indicators such as coefficient of determination (R), Nash-Sutcliffe efficiency (NSE), percent bias (PBIAS), and root-mean-square error (RMSE). R, NSE, PBIAS, and RMSE values for SWAT (ANN with Architecture (2,27,1)) models during calibration are 0.

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Background: Intellectual disability (ID) is a condition that varies widely in both its clinical presentation and its genetic underpinnings. It significantly impacts patients' learning capacities and lowers their IQ below 70. The solute carrier (SLC) family is the most abundant class of transmembrane transporters and is responsible for the translocation of various substances across cell membranes, including nutrients, ions, metabolites, and medicines.

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Article Synopsis
  • The research focuses on KRuF and KOsF fluoride materials as new semiconductor options for renewable energy devices, exploring their properties using computational methods.
  • The study confirms that both materials are indirect semiconductors, with band gap values of 2.1 eV for KRuF and 1.7 eV for KOsF, indicating their potential for electronic applications.
  • Mechanical properties, including ductility and optical performance in the UV range, were analyzed, suggesting that both materials hold promise for future use in optoelectronic devices.
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Genome-wide identification and gene expression analysis of GHMP kinase gene family in banana cv. Rasthali.

Mol Biol Rep

November 2023

Plant Tissue Culture and Genetic Engineering Lab, Department of Biotechnology, S.A.S. Nagar, Ministry of Science and Technology (Government of India), National Agri-Food Biotechnology Institute (NABI), Sector 81, Knowledge City, Mohali, Punjab, 140306, India.

Background: The GHMP kinase gene family encompasses ATP-dependent kinases, significantly involved in the biosynthesis of isoprenes, amino acids, and metabolism of carbohydrates. Banana is a staple tropical crop that is globally consumed but known for high sensitivity to salt, cold, and drought stresses. The GHMP kinases are known to play a significant role during abiotic stresses in plants.

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In order to address the pressing demand for newer broad-spectrum antifungal medicines with enhanced activity, computer modelling was utilised to rationally develop newer antifungal azole-based drugs. Based on the drug and active sites of the 14 alpha-Demethylases (LAD) of the prominent fungal pathogen interaction, Novel triazole-linked melatonin and isatin derivatives 7a-d and 8a-d were synthesised using bioisosterism. Besides the experimental synthesis and subsequent characterization, the present study focused on obtaining optimised geometries, frequency calculations, and TD-DFT studies of the synthesised molecules.

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Turmeric ( L.), a significant commercial crop of the Indian subcontinent is widely used as a condiment, natural dye, and as a cure for different ailments. Various bioactive compounds such as turmerones and curcuminoids have been isolated from that have shown remarkable medicinal activity against various ailments.

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Efficient and excellent nanoparticles are required for the degradation of organic dyes in photocatalysis. In this study, silver-manganese oxide nanoparticles (Ag-Mn-NPs) were synthesized through a wet chemical precipitation method and characterized as an advanced catalyst that has enhanced photocatalytic activity under sunlight irradiation. The nanoparticles were characterized using scanning electron microscopy (SEM), XRD, UV-vis light spectra, and energy-dispersive X-ray (EDX) spectroscopy, revealing their spherical and agglomerated form.

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