2 results match your criteria: "Government Medical College Rajouri[Affiliation]"
Comparison of BTP, NGAL, KIM-1, & ADMA biomarkers in CKD and non-CKD subjects.
Int J Biochem Mol Biol
June 2023
Department of Biochemistry, Government Medical College Rajouri, J&K, India.
Introduction: New biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), a member of the lipocalin family, and kidney injury molecule-1 (KIM-1) have been utilised in recent years to identify the development of chronic kidney disease (CKD). However, attempts to use them as broad markers to check for renal injury in patients and to pinpoint the kidney injury site have been unsuccessful. Therefore the search for an ideal panel of biomarkers predicting progression of CKD is still ongoing.
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- Terlipressin is a vasopressin analogue used to treat bleeding esophageal varices and hepatorenal syndrome in liver cirrhosis patients.
- Though generally safe, it can cause serious adverse effects such as skin necrosis in areas like the abdomen, extremities, and scrotum.
- A rare case is presented where a 48-year-old male developed skin necrosis in his lower extremities due to terlipressin while being treated for hepatorenal syndrome.