Evaluation of salivary biomarker interleukin-6 in oral squamous cell carcinoma and oral potentially malignant disorders - A comparative cross-sectional South Indian study.

Background: Oral squamous cell carcinoma (OSCC) accounts for nearly 90% of oral malignancies and represents a major global health care problem. It is often preceded by oral potentially malignant disorders (OPMD). Although regular clinical examination forms the backbone for oral cancer screening, subtle lesions go unnoticed and there is a need for more sensitive and specific molecular biomarkers in mass screening of population.

Comparative histologic evaluation of teeth decalcified by conventional method versus microwave induced decalcification.

Introduction: Complete demineralization of hard tissues with preservation of organic components to retain their tissue architecture and to obtain thin section for histological examination is done by a process known as "decalcification". Tooth decalcification may be achieved by subjecting the tissue to a decalcifying chemical agent and employing heat, vacuum, or electric current to enhance the procedure. Completion of decalcification is adjudged by determination of end-point.

Evaluation of Effect of Laser in Root Canal Disinfection in Pulp Regenerative Therapy: A Systematic Review.

The evaluation of the effect of laser in disinfection of root canal in pulp regenerative therapy, if found effective laser can be used for root canal disinfection in cases of regenerative endodontic therapy. This study includes a systematic review addressing the question of whether laser is effective in root canal treatment in regenerative endodontic therapy. Randomized controlled trials (RCTs), case series, and animal studies evaluating the effect of laser-assisted endodontic irrigation in pulp regenerative therapy were included.

Comparison of Microleakage and Bond Strength in Metal and Ceramic Brackets Cured by Conventional and Transillumination Methods: An Evaluation.

Background: The study explores the impact of microleakage on bracket (metal/ceramic) debonding and the occurrence of white spot lesions during orthodontic treatment. Various curing techniques are employed to assess shear bond strength (SBS) and microleakage in both metal and ceramic brackets.

Materials And Methods: A total of 120 samples were divided into six groups, each consisting of 20 samples.

Surface Prereacted Glass Ionomer Varnish as a Multifaceted Anticaries Agent: Investigating its Inhibitory Effects on Demineralization and Biofilm Formation on Primary Tooth Enamel.

Background: Dental caries remains a significant oral health concern, particularly in young children. With an increasing interest in preventive strategies, pediatric and preventive dentistry research is now more focused on developing newer materials and techniques to coat the primary teeth to prevent the onset of new carious lesions. While traditional preventive measures such as fluoride application and sealants have been effective in reducing caries incidence, there is still a need for innovative approaches.

Clinical and Radiographic Efficacy of Low-level Laser Therapy and Formocresol as Pulpotomy Agents in Primary Molars: A Systematic Review and Meta-analysis.

Research Question: To evaluate the effectiveness of low-level laser therapy (LLLT) as a pulpotomy agent in primary molars.

Research Protocol: This systematic review followed the recommendation of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline 2020.

Literature Search: An electronic search of the databases was performed to find the effectiveness of LLLT over formocresol as a pulpotomy agent in primary molars in children aged between 3 and 10 years.

Evaluation of the association between periodontal disease and total cancer risk: A cross-sectional study.

Background: The body is in a continuous state of inflammatory burden due to local and systemic inflammation, which is triggered in periodontal tissues in response to microorganisms. A number of studies have linked periodontitis to systemic diseases such as diabetes mellitus, cardiovascular disease and respiratory disease. Periodontal inflammation acts as a focus of infection, which can cause detrimental effects on distant target organs.

Evaluation of Early Childhood Caries and Its Association with Risk Factors among School Children: A Cross-sectional Study.

Aim: The study aimed to assess early childhood caries and its correlation with risk variables among school children.

Materials And Methods: 242 children under the age of 5 years were clinically assessed and to ascertain early childhood caries, a validated structured questionnaire was utilized. Demographic data (four questions) and oral health-related activities questions (two questions) were included.

Economic Accessibility of Orthodontic Care in India: A Cross-Sectional Study.

Background The rising demand for orthodontic services is juxtaposed with concerns regarding economic accessibility for diverse socioeconomic groups. Aim This study aims to investigate the economic accessibility of orthodontic care in India through a comprehensive questionnaire-based approach. Material and methods The survey involved a random sample of 5,000 patients actively seeking orthodontic treatment, recruited from both dental college clinics and private dental practices.

Combination of Silver Diamine Fluoride and Hall Technique for Caries Management in Primary Molars: A Randomized Controlled Trial.

Aims And Background: Combination of different noninvasive caries arresting approaches may improve the effectiveness and success rate of individual procedures for caries management. The purpose of this study was to evaluate clinical and radiographic success rate of a combination of 38% silver diamine fluoride (SDF) application and Hall technique (HT) for the management of dentinal caries in primary molars and compare it with conventional stainless steel crown (SSC) restoration.

Materials And Methods: Children aged 4-8 years, having carious primary molars with the International Caries Detection and Assessment System (ICDAS) score of 5 or 6, were randomly assigned to treatment group A or B.

Cross-sectional study exploring the prevalence and clinical manifestations of acute diarrhea among under-5 children in primary care hospital in Democratic Republic of the Congo.

Background: Acute diarrhea (AD), which is defined as frequent passing of liquid stools compared to normal, is a serious and worrying problem and remains a concern for healthcare systems because of its high mortality cause in children under 5 years old. The authors' study aimed to present the prevalence and to describe the clinical manifestation of AD among under-5 children.

Methods: From June 2022 to May 2023, the authors conducted a retrospective, descriptive and cross-sectional study including all patients aged 0-5 years hospitalized for AD.

A two-step hydrothermal method for micro/nanotextured titanium implants and their integration outcomes in goat mandible.

Background: A crucial aspect of contemporary dental implant research is modifying implant microdesign to achieve early and robust osseointegration. This study describes a new facile subtraction approach for microdesign modification of titanium implants using akali-hydrothermal followed by ion-exchange reaction (AHIE) in a salt solution, and compares osseointegration performance to machined titanium alloy (negative control) implants.

Methods: The morphology, wettability, and roughness of the implant surfaces were evaluated.

Drug delivery systems in periodontitis: A visualization and bibliometric analysis.

Objective: This study aimed to evaluate research hotspots and trends in the field of periodontitis and drug delivery systems from the perspective of bibliometrics.

Methods: Publications related to periodontitis and drug delivery systems between 2001 and 2023 were retrieved from the Web of Science Core Collection database. Bibliometric analysis was conducted using VOSviewer, CiteSpace, and the R package "bibliometrix.

Maxillomandibular Fixation Verses Open Reduction and Internal Fixation in Mandibular Fractures-Effect on Pulmonary Functions.

Introduction: Mandibular fractures have significant influence on oropharyngeal and laryngopharyngeal portions of the upper airway. They can be managed by MMF or ORIF.

Aim & Objectives: To quantify and compare the effects of MMF with ORIF on the pulmonary functions of the patients undergoing treatment for mandibular fractures.

Toxicity profile of standardized Krishna Vajra Abhraka bhasma made from biotite mica.

Introduction: The Bhasmas, herbo-minerals, are reported to produce adverse effects when used clinically. Therefore, the present study aimed to assess the safety of Krishna Vajra Abhraka Bhasma (KVB), through acute and subacute toxicity testing.

Materials And Methods: After ethics committee approval, total 66 Wistar albino rats weighing 180-200 gms were used.

Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists.

Background: Nigeria faces a critical shortage of healthcare professionals yet experiences a significant annual exodus of doctors and dentists. This alarming trend threatens the country's ability to provide equitable healthcare.

Objective: This study investigated the patterns and determinants of migration among doctors and dentists who graduated from the University of Benin, Nigeria, 15 years ago.