Pharmaceutical characterization and exploration of Arkeshwara rasa in MDA-MB-231 cells.

Background: The diverse specificity mode of cancer treatment targets and chemo resistance demands the necessity of drug entities which can address the devastating dynamicity of the disease.

Objectives: To check the anti-tumour potential of traditional medicine rich in polyherbal components and metal nanoparticle namely Arkeshwara rasa (AR).

Material Methods: The AR was prepared in a modified version with reference from Rasaratna Samuchaya and characterized using sophisticated instrumental analysis including XRD, SEM-EDAX, TEM, TGA-DSC, and LC-MS and tested against the MDA-MB-231 cell line to screen cell viability and the cytotoxicity with MTT, SRB and the AO assay.

Preliminary data on cytotoxicity and functional group assessment of a herb-mineral combination against colorectal carcinoma cell line.

Objectives: The invasive screening methods and the late stage diagnosis of colorectal carcinoma (CRC) are contributing for the devastative prognosis. The gradual shift of the disease pattern among younger generations requires the implementation of phytochemicals and traditional medicines. (AR) is a herb-mineral combination of /incinerated copper ashes and /mercury sulphide levigated with leaf juice, root decoction and the decoction of three myrobalans (, , decoction)/ decoction.

Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability.

Anthocyanins (ACNs) have attracted considerable attention for their potential to modulate the immune system. Research has revealed their antioxidant and anti-inflammatory properties, which play a crucial role in immune regulation by influencing key immune cells, such as lymphocytes, macrophages, and dendritic cells. Moreover, ACNs contribute towards maintaining a balance between proinflammatory and anti-inflammatory cytokines, thus promoting immune health.

Validation of the Ayurvedic construct, Rasadhatudushti, in adults at risk of cardiovascular diseases - A mixed-method study.

Background: Rasadhatudushti (RD), the deranged state of Rasadhatu, is a construct in Ayurveda mentioned as the cause of diseases affecting the circulatory channels and the heart, collectively called cardiovascular diseases (CVD). It is a morbid condition generic to some other disorders, hence is non-specific to CVD. It was observed that RD was present in majority of acute coronary artery disease in a cross-sectional, descriptive study in 250 patients stabilized after an acute episode.

Personalized ayurvedic approach involving Sadyo Vamana in COVID-19 management: A case report.

Sars Cov-2 has emerged as a global threat worldwide. At present, India is the second worsely-hit nation by COVID-19. Since it is a novel virus, there is no specific treatment strategy available at present.

Comparative HPTLC fingerprinting profile and GC-MS analysis of raw and purified () by purification method.

Background: is an oleo gum resin obtained from the plant (Arn.) Bhand., used in medicines for various ailments like anti-inflammatory conditions, hyperlipidemia, thyroid disorders etc.

A comparative diuretic evaluation of fruit and root of ( Linn.) in albino rats.

Background: (root of Linn.) is one among the ingredients of , a group of ten medicinal plants principally comprising roots as the useful part. In practice instead of root, fruit of is widely used in most of the preparations of in Kerala.

Characterization and antimicrobial study of ) .

Background: (TMP) is a cardio-tonic (), styptic ( ), astringent () formulation frequently used in varieties of bleeding disorders such as bloody diarrhea (), (bleeding piles), and disorders of excessive menstruation (). Still, no published data is available regarding its characterization.

Aim: To generate a fingerprint for raw and processed TMP using sophisticated instrumental techniques to assess antimicrobial activity of TMP.

Efficacy of and somnifera L.) Dunal powder in primary insomnia in elderly male: A randomized open-label clinical study.

Background: Decreased ability to fall asleep and/or stay asleep with daytime effects of sleep deprivation is identified as primary insomnia. Elderly due to the predominant in the body are easily affected by this problem. (nourishing nasal drop) with and oral administration of ( (L.

A retrospective analysis of the effect of the intervention of in COVID-19 positive cases in Madhya Pradesh.

Introduction: Coronavirus disease (COVID-19) is a newly identified strain of corona virus that causes illness ranging from the clinical features similar to the common cold to a fatal condition due to severe respiratory failure. According to the WHO, there have been more than 26.3 million confirmed COVID-19 cases in more than 190 countries to date.

Diet and lifestyle-related factors associated with (type 2 diabetes): A cross-sectional survey study.

Background: Lifestyle disorders are the leading cause of death and disability worldwide. Type 2 diabetes is one such disease with high incidence in low- and middle-income countries such as India. Changed lifestyle, lack of exercise, increased consumption of fatty, fast-food items, improper dietary habits and sedentary life are the main contributory factors for this, which are showing upward trend in India.

Prevalence of Shukra vega dharana in an Indian population: A cross sectional survey protocol.

Background: Despite being an important aspect of health and quality of life, individuals tend to suppress natural sexual urge ('Shukra vega') due to a variety of factors. Unless managed appropriately through self-regulatory mechanisms, suppressed sexual urge ('Shukra vega dharana', SVD) not only causes psychological suffering but may also put other basic needs at risk. Adult, married, males who are either living away from their spouse for long durations or separated or divorced are at a considerably higher risk of developing SVD as compared to others.

7th International Conference on Human Values in Higher Education: Education for holistic human health.

The 7th International Conference on "Human Values in Higher Education: Education for Holistic Human Health" (ICHVHE-18) was held from April 26 to 28, 2018, at Khesar Gyalpo University of Medical Sciences of Bhutan, Thimphu, Bhutan. This conference also celebrated the 50th year of Indo-Bhutan friendship. ICHVHE-18, was the culmination of the collaborative efforts of eight universities, two from Bhutan and six from India.

Intelligence quotient and concept of Deha-Mānasa Prakṛti in Ayurveda.

Background: Ayurveda has classified humans according to Deha-Mānasa prakṛti. It has given equal emphasis to both physical and psychological status of the individual. Constitution or configuration is an individual's peculiar set up of body and mind.

Lifestyle related factors associated with (obesity) - A cross-sectional survey study.

Introduction: The burden of lifestyle disorders is rapidly increasing worldwide. Modernization, affluence, science and technological development lead to still more sedentary life styles. By exposing oneself to all these factors human being unknowingly invited a number of diseases, out of which (obesity) is one which disturbs physical, mental and social health of an individual.

Toxicity study of Lauha Bhasma (calcined iron) in albino rats.

Background: Lauha Bhasma (LB) is a complex herbomineral preparation widely used as an Ayurvedic hematinic agent. It is an effective remedy for chronic fever (jīrṇa jvara), phthisis (kṣaya), Breathlessness (śvāsa) etc., and possesses vitality enhancing (vājīkara), strength promoting and anti aging (rasāyana) properties.

Standardization and quality control parameters for Muktā Bhasma (calcined pearl).

Background: Muktā Bhasma (MB) is a traditional Ayurvedic preparation for cough, breathlessness, and eye disorders and is a powerful cardiac tonic, mood elevator, and known to promote strength, intellect, and semen production.

Objectives: The present research work was conducted to generate fingerprint for raw and processed MB for quality assessment and standardization using classical and other techniques.

Setting And Design: Three samples of MB were prepared by purification (śodhana) of Muktā (pearl) followed by repeated calcinations (Māraṇa).

Comparative study on the effect of Saptamrita Lauha and Yoga therapy in myopia.

Background: Myopia is very common ophthalmic disease especially in children and adolescence. In Ayurvedic texts, only by the main feature impairment of distant vision myopia can be correlated with Drishtigata Rogas (2(nd) Patalgata Timira).

Aim: To compare the effect of Saptamruta Lauha and Yoga therapy in myopia.

A comparative analytical study of Prasarani [Merremia tridentata Hallier. f. and Paederia foetida Linn].

Prasarani is one of the drugs used in Vata Rogas such as Amavata, Avabahuka, etc. Among the different source plants of Prasarani, the plant Merremia tridentata Haller.f.

Applicability and importance of Caraka's concept of Aaturaparijnana Hetawah in understanding a patient.

Many concepts in Ayurveda are untouched or unexplored till date. One of such concepts to understand the healthy and unhealthy persons is that of the Aaturaparijnana Hetawah (APH), which is only mentioned in Caraka Samhita. The descriptions about Dushya, Desha, Bala, Kala, Prakriti, etc.

A comparative study of Bilvadi Yoga Ashchyotana and eye drops in Vataja Abhishyanda (Simple Allergic Conjunctivitis).

Simple allergic conjunctivitis is the most common form of ocular allergy (prevalence 5 - 22 %). It is a hypersensitivity reaction to specific airborne antigens. The disease Vataja Abhishyanda, which is due to vitiation of Vata Pradhana Tridosha is comparable with this condition.

A randomized controlled clinical trial to assess the efficacy of Nasya in reducing the signs and symptoms of cervical spondylosis.

This work was designed to assess the efficacy of Nasya in reducing the signs and symptoms of cervical spondylosis. The patients attending the O. P.