Impact of cranioskeletal trauma on the development of endogenous intoxication syndrome in rats of different ages.

Objective: Aim: The aim of the study was to determine the impact of cranioskeletal trauma (CST) on the development of endogenous intoxication syndrome in rats of different ages.

Patients And Methods: Materials and Methods: The experiments involved 147 white male Wistar rats of different age groups. The first experimental group included sexual immature rats aged 100-120 days.

MICROSCOPIC CHANGES OF THE KIDNEY IN EXPERIMENTAL HYPERHOMOCYSTEINEMIA ON THE BACKGROUND OF HYPER- AND HYPOTHYROIDISM.

Hyper- and hypothyroidism are two typical clinical conditions that can cause a variety of metabolic changes, including impaired sulfur-containing amino acids metabolism, increased risk of cardiovascular disease, renal dysfunction, and renal failure. Hypothyroidism has been shown to be associated with increased serum creatinine, decreased glomerular filtration rate, and an increased risk of chronic kidney disease. At the same time, the pathophysiological mechanisms of renal dysfunction induced by excessive iodothyronine secretion are poorly understood.

[Long-term results of the use of lyophilized xenodermoimplants in the surgical treatment of patients with cicatricial stenosis of the larynx].

Unlabelled: Purpose is to study the long-term results of patients with cicatricial stenosis of the larynx treated with use lyophilized xenodermoimplants for postoperative wound plasty.

Material And Methods: The results of treatment of 34 patients (age from 32 to 56 years) with cicatricial stenosis of the larynx were analyzed. A fundamentally new method of surgical treatment of such patients has been developed and introduced into practice, in which lyophilized xenodermoimplants were used for plasty of the wound surface.

Implementation of programmed cell death in circulating neutrophils and its special characteristics in experimentally induced hyperhomocysteinemia in a setting of thyroid dysfunction.

Unlabelled: Cardiovascular (CV) disease continues to be the main cause of morbidity and mortality in worldwide. Hyperhomocysteinemia (HHCy) is a novel metabolic risk factor of vascular damage. In addition to that, there is evidence that HHCy management with folic acid and vitamin B supplements prevents atherosclerosis and its sequelae.