Highlighting antibiotic-free aquaculture by using marine microbes as a sustainable method to suppress Vibrio and enhance the performance of brine shrimp (Artemia franciscana).

Brine shrimp nauplii are widely used as live food in fish and shellfish aquaculture but they may transmit pathogenic Vibrio to the target species causing significant economic loss. Heavy usage of antibiotics is expensive and environmentally damaging. Use of natural microbes as probiotics for disease management is a more sustainable strategy.

Hippocampal nicotinic acetylcholine receptor signaling mediates the anti-allodynic effect of ketamine and morphine on neuropathic pain.

The present study investigated the involvement of hippocampal nicotinic acetylcholine receptors (nAChRs) in the anti-allodynic effect of ketamine/morphine on neuropathic pain in adult male Wistar rats. Morphine or ketamine administration decreased the percentage of maximum possible effect (MPE%), indicating an analgesic effect. The most significant decrease occurred with a 5 mg/kg dose of morphine (average MPE% = 98), while a 0.

The Use of Extract in Ameliorating Heat Stress-Induced Oxidative Damage and Improving Growth Efficiency in Carp Juveniles ().

Herbal extracts have been successfully used as feed additives in fish culture with attractive growth-promoting, immunostimulant, antimicrobial, and antioxidant properties for several fish and shellfish species. Therefore, we have designed a feeding trial to assess the impacts of dietary incorporation of extract (PAE) on common carp (). For this purpose, five isonitrogenous (35% protein) and isocaloric (~4,000 kcal/kg) diets have been supplied by supplementing PAE at the varying inclusion levels as 0.

Effects of Dietary Yeast, , and Costmary, , Essential Oil on Growth Performance, Digestive Enzymes, Biochemical Parameters, and Disease Resistance in Nile Tilapia, .

The present study assessed the effects of dietary yeast, , and costmary, , essential oil on growth performance, biochemical parameters, and disease resistance of Nile tilapia, . Four diets containing 1 g/kg yeast (Sc), 0.1 g/kg costmary essential oil (Tb), 1 g/kg yeast + 0.

Anxiolytic- and antidepressive-like effects of harmaline in mice are mediated via histamine H3 receptor blockade.

Many neuropsychiatric disorders can be caused by neurotransmitter dysfunction. Experimental studies have demonstrated that histamine and the harmaline affect physiological processes through interaction with other neurotransmitter systems. The objective of these experiments was to investigate the involvement of the histaminergic system in the effects of harmaline on anxiety- and depressive-related effects in male NMRI mice.

Enhancing bioactivity of (Curtis) essential oil through novel nanoemulsion formulation.

The main focus of this study was to create a stable and efficient nanoemulsion (NE) using essential oil (EO). Various factors affecting the NE's stability were optimized including oil %, Tween 80%, time of sonication, and its accelerated stability was examined. The research also considered the antibacterial, antifungal, and larvicidal effects of the optimized NE (B10).

Classification and prediction of drought and salinity stress tolerance in barley using GenPhenML.

Genetic and agronomic advances consistently lead to an annual increase in global barley yield. Since abiotic stresses (physical environmental factors that negatively affect plant growth) reduce barley yield, it is necessary to predict barley resistance. Artificial intelligence and machine learning (ML) models are new and powerful tools for predicting product resilience.

Detection of closely linked QTLs and candidate genes controlling germination indices in response to drought and salinity stresses in barley.

The aim of current study was to identify closely linked QTLs and candidate genes related to germination indices under control, salinity and drought conditions in barley. A total of nine (a major), 28 (eight major) and 34 (five major) closely linked QTLs were mapped on the seven chromosomes in response to control, drought and salinity conditions using genome-wide composite interval mapping, respectively. The major QTLs can be used in marker-assisted selection (MAS) projects to increase tolerance to drought and salinity stresses during the germination.

Micromorphological study of some Salsola species (Amaranthaceae) in Iran and its systematic significance using scanning electron microscopy.

Using scanning electron microscopy (SEM), six Salsola species from Iran were examined for their epidermis, seed, and fruit micromorphology. Among them were S. brachiata from section Heterotricha, S dendroides, S.

Volatile oil constituents, antioxidant and antibacterial activities of L. in different areas of Iran.

The genus of is the largest genus of Caprifoliaceae family. This study revealed the composition, antioxidant, and antibacterial actions of essential oils of L. in different areas of Iran; Qom, Mashhad, Shiraz.

A novel collocation method with a coronavirus optimization algorithm for the optimal control of COVID-19: A case study of Wuhan, China.

In this study, we develop a numerical optimization approach to address the challenge of optimal control in the spread of COVID-19. We evaluate the impact of various control strategies aimed at reducing the number of exposed and infectious individuals. Our novel approach employs Legendre wavelets, their derivative operational matrix, and a collocation method to transform the COVID-19 transmission optimal control model into a nonlinear programming (NLP) problem.

The genetically modified human foreskin fibroblast cell line (YhFF#8) stably expressing gene: A lab resource report.

Background: Stable Cas9 (CRISPR-associated protein 9)-expressing cell lines have emerged as valuable tools in genetic research, enhancing the efficiency of the CRISPR/Cas9 system and streamlining gene editing procedures. These cell lines enable simultaneous editing of multiple genes and reduce the overall editing time.

Objective: This study aimed to develop a stable human fibroblast cell line capable of genetic conversion into a mutant form, serving as a cellular model for a specific genetic disease.

Spatial and temporal distribution of physicochemical parameters of water in Gorgan Bay (the southeast of the Caspian Sea - Iran): Fundamentals for the monitoring of the Caspian Sea coastal areas.

Gorgan Bay as a main part of the Miankaleh (a natural biosphere reserve registered by UNESCO) is one of the richest ecological area in the West Asia and very important internationally recognized refuge for the wildlife. To date, multi physicochemical parameters have not been examined on a large scale. To fill this knowledge gap, the present study aimed to explore the seasonal and spatial variability of water quality parameters of the bay.

Crataegus pentagyna willd. Fruits, leaves and roots: phytochemicals, antioxidant and antimicrobial potentials.

Background: The hawthorn has recently been used as a popular herbal medicine in food applications and phytotherapy, especially for the cardiovascular system.

Methods: In this study, phytochemicals were evaluated by LC-ESI-MS, GC-MS, and biological activity, including antioxidant (DPPH test) and antibacterial (broth dilution assay), in different extracts of Crataegus pentagyna fruit, leaf, and root.

Results: Globally, 49 phenolics were tentatively identified using HPLC-ESI-MS/MS in the hydro-methanolic extract of the fruit (major apigenin, caffeoylquinic acid derivative, and 4-O-(3'-O-glucopyranosyl)-caffeoyl quinic acid), 42 in the leaf (major salicylic acid, naringenin-6-C-glucoside, and naringin), and 33 in the root (major naringenin-7-O-neohesperidoside, isovitexin-2″-O-rhamnoside, and 4-O-(3'-O-glucopyranosyl)-caffeoyl quinic acid).

Assessment of microplastic contamination in some commercial fishes of the southern Caspian Sea and its potential risks.

This study examined the occurrence of microplastics (MPs) in the gastrointestinal tract (GIT) of 384 fishes classified into four species from 11 sites in 2022 from the southern part of the Caspian Sea. GITs of fishes were collected and digested in HO and KOH at 45 °C for 72 h. After filtration, extracted MPs were observed under a stereomicroscope, and selected MP particles were identified using FTIR.

Finding stable and closely linked QTLs against spot blotch in different planting dates during the adult stage in barley.

The common resistance to Spot Blotch (SB) and drought stress in barley was studied using a RILs population caused Kavir × Badia cross. These lines were inoculated with Cochliobolus sativus Gonbad isolate during the adult stage and were evaluated for three crop seasons in different planting dates. The different osmotic potentials during the flowering were regulated by changing the planting dates.

Exploring the microplastic pollution: Unveiling origins and varieties in coastal sediments and waters of the Bushehr Province, Persian Gulf, Iran.

In this study, microplastic (MP) pollution in the coastal sediments and tidal waters of Bushehr province in the Persian Gulf was comprehensively investigated. The sampling stations were selected based on their proximity to various human activities in January and February 2022, such as tourism, fishing, urban development and industry. The results showed that the abundance of MP associated with different human activities varied.

The fate of nitrogen in the Zarin-Gol River receiving trout farm effluent.

This study investigated the Zarrin-Gol River ecosystem in Iran to trace organic matter in the food web and evaluate the impact of aquaculture farm effluent using stable isotopes of nitrogen (δN) and carbon (δC). Using a previously-developed model (Islam 2005), we estimated that a trout farm in the vicinity released 1.4 tons of nitrogen into the river.

Health Risk Assessment of Heavy Metals in Marine Fish Caught from the Northwest Persian Gulf.

Marine fish may become contaminated as a result of environmental pollution including hazardous metals. Due to the presence of metalloids and toxic metals such as cadmium, lead, copper, and zinc in fish tissue, it may endanger health, considering the countless benefits of consuming fish, which can harm the human body if consumed in toxic amounts. Therefore, it is vital to monitor the concentration of metals in fish meat to ensure compliance with food safety regulations and protect the consumer.

Evaluating the industrial potential of naturally occurring proteases: A focus on kinetic and thermodynamic parameters.

Thermodynamic and kinetic parameters, such as enthalpy, entropy, and free energy, are crucial in evaluating enzyme stability and activity. These parameters, including the free energy of activation (ΔG) and the Gibbs free energy of inactivation (ΔG*), are important for predicting energy requirements and reaction rates. However, relying solely on these parameters is insufficient in selecting an enzyme for industrial processes.

Genomics and Physiology of Chlorophyll Fluorescence Parameters in L. under Drought and Salt Stresses.

To map the genomic regions and control chlorophyll fluorescence attributes under normal, salinity-, and drought-stress conditions in barley ( L.) at the seedling stage, an experiment was conducted in 2019-2020 using 106 F8 lines resulting from the cross between Badia × Kavir. Initially, the different chlorophyll fluorescence parameters were evaluated.

Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression.

The present study aimed to evaluate the functional interaction between the dopaminergic and glutamatergic systems of the mediodorsal thalamus (MD), the ventral hippocampus (VH), and the prefrontal cortex (PFC) in nicotine-induced anxiogenic-like behaviors. Brain-derived neurotrophic factor (BDNF) level changes were measured in the targeted brain areas following the drug treatments. The percentage of time spent in the open arm (% OAT) and open arm entry (% OAE) were calculated in the elevated plus maze (EPM) to measure anxiety-related behaviors in adult male Wistar rats.

A meta-analysis of microarray datasets to identify biological regulatory networks in Alzheimer's disease.

Alzheimer's Disease (AD) is an age-related progressive neurodegenerative disorder characterized by mental deterioration, memory deficit, and multiple cognitive abnormalities, with an overall prevalence of ∼2% among industrialized countries. Although a proper diagnosis is not yet available, identification of miRNAs and mRNAs could offer valuable insights into the molecular pathways underlying AD's prognosis. This study aims to utilize microarray bioinformatic analysis to identify potential biomarkers of AD, by analyzing six microarray datasets (GSE4757, GSE5281, GSE16759, GSE28146, GSE12685, and GSE1297) of AD patients, and control groups.

LncRNA MALAT1 signaling pathway and clinical applications in overcome on cancers metastasis.

In spite of its high mortality rate and difficulty in finding a cure, scientific advancements have contributed to a reduction in cancer-related fatalities. Aberrant gene expression during carcinogenesis emphasizes the importance of targeting the signaling networks that control gene expression in cancer treatment. Long noncoding RNAs (lncRNAs), which are transcribed RNA molecules that play a role in gene expression regulation, are a recent innovative therapeutic approach for diagnosing and treating malignancies.