Violence against infertile women in an Iranian setting.

Background: Infertility as a distressing condition, is associated with numerous psychological and social consequences for couples. In addition, there is evidence to suggest that infertility may contribute to the occurrence of violence against women. The aim of the study is to determine the prevalence and factors associated with violence against Iranian women with infertility.

Modeling the determinants of smoking behavior among young adults in Khuzestan province: a two-level count regression approach.

Purpose: This study investigates the determinants of smoking behavior among young adults in Khuzestan province, southwest Iran, using two-level count regression models. Given the high prevalence of smoking-related diseases and the social impact of smoking, understanding the factors influencing smoking habits is crucial for effective public health interventions.

Methods: We conducted a cross-sectional analysis of 1,973 individuals aged 18-35 years, using data from the Daily Smoking Consumption Survey (DSCS) in Khuzestan province collected in 2023.

Bayesian age-period-cohort projection of cancers in Iran: a modeling study.

Introduction: Cancer is a significant public health issue in Iran, and its incidence has been on the rise in recent years. The objective of this study is to predict the incidence of total cancer in Iran using a Bayesian age-period-cohort (APC) model.

Methods: Utilizing age-period-cohort modeling, this study assessed the multifaceted effects of age, period, and cohort on cancer incidence during the period spanning 2005 to 2017.

Investigating the effect of teaching assistants (TA) on the level of satisfaction of undergraduate anesthesia students with training in the internship unit.

Background: Clinical training in the internship unit is the heart of professional training, and teaching assistants can be considered an essential component in the clinical training program. Therefore the present study was conducted to investigate the effect of teaching assistants (TA) on the degree of satisfaction of undergraduate students of Anesthesia with training in the internship unit.

Materials And Methods: This descriptive-cross-sectional study was conducted in 2023.

Association of G12D mutation in the KRAS gene with HPV and EBV in gastrointestinal cancer tissues.

Objective: This study aimed to explore the potential relationship between viral infections and gastrointestinal (GI) malignancies, focusing on the presence of KRAS G12D mutations. Specifically, we investigated the association of viral agents, including human papillomavirus (HPV) and Epstein-Barr virus (EBV), with KRAS G12D mutations in GI cancers to better understand their combined role in cancer development.

Methods: This cross-sectional study comprised 92 patients diagnosed with GI cancer and 100 healthy individuals in the control group.

Body size and occupational physical activity during the life course and gastrointestinal cancers.

Evidence on the associations of body size and occupational physical activity (PA) during the life course with gastrointestinal cancers is inconclusive. We analyzed data from the Golestan Cohort Study, a population-based prospective cohort study from Iran, with 50,045 individuals aged 40-75 years enrolled during 2004-2008 and followed through April 2023. Body size during adolescence, early adulthood, and at cohort baseline was assessed using validated pictograms.

Comparison of the Effect of Maternal Breast Milk Odor, Facilitated Tucking, and Nonnutritive Sucking Applied to Preterm Neonates During Heel Stick on Pain and Physiological Parameters: A Randomized Controlled Trial.

Preterm infants in the neonatal intensive care unit (NICU) frequently undergo painful procedures, which can lead to both short-term and long-term complications, including potential mortality. Effective pain management is crucial in this context. Although numerous studies have explored non-pharmacological pain relief methods for preterm infants, no research has simultaneously compared the effects of maternal breast milk odor, facilitated tucking, and nonnutritive sucking.

Sinus mucocele leads to unilateral proptosis in an infant patient with cystic fibrosis: a literature review and a case report study.

Introduction And Importance: Cystic fibrosis (CF) is a widespread life-shortening recessive genetic disease and can present with sinus mucocele. Sinus mucocele is a rare condition, with limited prevalence data on unilateral proptosis.

Case Presentation: The authors present a case of a 19-month-old boy with CF who experienced worsening proptosis and exotropia in his right eye.

Perirenal Adipose Tissue: Clinical Implication and Therapeutic Interventions.

Perirenal adipose tissue (PRAT) has been identified as an important factor in local and general homeostasis of the human body and is especially important in regulating renal and cardiovascular functions. It has also been identified as a crucial risk factor to consider in cardiovascular and renal disorders, malignancies, and various other diseases. Having a concrete idea of the effects of therapeutic interventions on the size and metabolism of the PRAT could prove highly beneficial.

Prevalence of Fungal Infections in Pemphigus Patients: A Systematic Review and Meta-Analysis.

Background: Pemphigus is a life-threatening autoimmune disease characterised by blistering skin and/or mucous membranes. The present study aimed to determine the prevalence of fungal infections in the pemphigus population.

Methods: Different databases were searched to gain access to all studies on the prevalence of fungal infections published up to the 31st of May 2024.

Repurposing raltegravir for reducing inflammation and treating cancer: a bioinformatics analysis.

Inflammation is a defensive mechanism that safeguards the human body against detrimental stimuli. Within this intricate process, ADAM17, a zinc-dependent metalloprotease, emerges as an indispensable element, fostering the activation of diverse inflammatory and growth factors within the organism. Nonetheless, ADAM17 malfunctions can augment the rate of growth, inflammatory factors, and subsequent damage.

Clinical challenges in bone tissue engineering - A narrative review.

Bone tissue engineering (BTE) has emerged as a promising approach to address large bone defects caused by trauma, infections, congenital malformations, and tumors. This review focuses on scaffold design, cell sources, growth factors, and vascularization strategies, highlighting their roles in developing effective treatments. We explore the complexities of balancing mechanical properties, porosity, and biocompatibility in scaffold materials, alongside optimizing mesenchymal stem cell delivery methods.

Comparative Assessment of Post-Fatigue Resistance of Mandibular First Molars Restored With Polyether Ether Ketone and Lithium Disilicate Endocrowns.

Contemporary dentistry focuses on more conservative treatment options such as endocrown restorations and application of dental materials with higher resemblance to tooth structure. Polyether ether ketone (PEEK) polymer is a material used for the fabrication of endocrowns. This study aimed to compare the post-fatigue resistance (PFR) of mandibular first molars restored with PEEK and lithium disilicate (LS) endocrown restorations.

A novel frameshift variant in the TMPRSS3 gene causes nonsyndromic hearing loss in a consanguineous family.

Background: Hearing Loss (HL) is the most common sensorineural condition in humans. Mutations in the TMPRSS3 gene (DNFB8/10 locus) have been linked to autosomal recessive non-syndromic hearing loss (ARNSHL).

Methods: Whole-exome sequencing (WES) was utilized to identify disease-causing variants in a proband from Iran with ARNSHL who presented clinically with sensorineural, bilateral, and prelingual HL.

Anti-biofilm activity of carvacrol-thymoquinone nanocarriers on vulvovaginal candidiasis isolates.

Given the recurrent nature of vulvovaginal candidiasis (VVC), the restricted availability of effective antifungal agents, and the recent rise in drug resistance, this study sought to assess the antifungal efficacy of carvacrol-thymoquinone delivered via a nanocarrier on Candida isolates obtained from patients with VVC. Isolates were identified using phenotypic and genotypic methods. Nanocarriers were synthesized using the thin-film hydration method.

The Cancer Incidence Pattern in Isfahan Province: An Industrial Region in the Central Part of Iran.

We aimed to study age-standardized incidence rates (ASRs) of different cancer sites in Isfahan province, an industrialized city in the central part of Iran. We obtained cancer incidence data from 2014 to 2018 in the Isfahan population-based cancer registry (PBCR). We studied quality indicators of PBCR and the validity of residential places for cancer patients.